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رادار التجارب AI
حالة التجربة السريرية NCT04649242 لـ Pediatric Migraine هي يقبل مشاركين. اطلعوا على جميع التفاصيل في عرض البطاقة الخاص برادار التجارب السريرية وأدوات اكتشاف الذكاء الاصطناعي. أو يمكنكم طرح أي سؤال هنا.
تجربة واحدة تطابق معايير الفلتر
عرض البطاقة
العودة إلى البحث

Randomized Study in Children and Adolescents With Migraine: Acute Treatment المرحلة الثالثة ٢٬١٠٠ عشوائية المراهقون

يقبل مشاركين
تفاصيل التجربة السريرية متاحة بشكل أساسي باللغة الإنجليزية. ومع ذلك، يمكن لـ رادار التجارب AI مساعدتك؛ ما عليك سوى النقر على «وصف الدراسة» لعرض ومناقشة معلومات التجربة باللغة التي اخترتها.
التجربة السريرية NCT04649242 مصممة لدراسة علاج لـPediatric Migraine. إنها تجربة تدخُّلية من المرحلة الثالثة وهي يقبل مشاركين. بدأت في ٢ جمادى الآخرة ١٤٤٢ هـ مع خطة لتجنيد ٢٬١٠٠ مشاركًا. تقودها فايزر، ومن المتوقع اكتمالها بحلول ٢٤ شعبان ١٤٥٠ هـ. تم تحديث البيانات الأخيرة من ClinicalTrials.gov في ١ شوال ١٤٤٧ هـ.
الملخص
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
العنوان الرسمي

Phase 3, Multicenter, Randomized, Double-blind, Group Sequential, Placebo-controlled Study to Assess Efficacy and Safety of Rimegepant for the Treatment of Migraine (With or Without Aura) in Children and Adolescents ≥ 6 to < 18 Years of Age

الحالات الطبية
Pediatric Migraine
معرّفات دراسة أخرى
  • BHV3000-311
  • C4951002 (معرف آخر) (Alias Study Number)
  • 2020-003517-35 (معرف السجل) (CTIS (EU))
  • 2024-512743-23-00 (معرف السجل) (CTIS (EU))
NCT معرّف
NCT04649242
تاريخ البدء (فعلي)
2021-01-15
آخر تحديث مُنشور
2026-03-20
تاريخ الاكتمال (المقدر)
2029-01-09
عدد المشاركين المخطط لهم
٢٬١٠٠
نوع الدراسة
تدخُّلية
المرحلة
المرحلة الثالثة
الحالة
يقبل مشاركين
الكلمات الرئيسية
Migraine
Acute treatment
Phonophobia
Photophobia
Nausea
Pediatric
Children
Adolescent
Pediatric Migraine
الغرض الأساسي
العلاج
طريقة توزيع المشاركين
عشوائي
نموذج التدخل
تصميم تسلسلي
التعمية
ثلاثي
مجموعات/التدخلات
مجموعة المشاركين/الذراعالتدخل/العلاج
مقارن نشطBHV3000 (active drug)
BHV3000 (rimegepant) 75 mg or 50 mg ODT
Rimegepant/BHV3000
BHV3000 (rimegepant) 75 mg or 50 mg ODT
مقارن بالدواء الوهميPlacebo
Matching 75 mg or 50 mg ODT placebo
الدواء الوهمي المطابق
Matching 75 mg or 50 mg ODT placebo
النتيجة الرئيسية
مقياس النتيجةوصف القياسالإطار الزمني
To evaluate the efficacy of rimegepant compared with placebo in the acute treatment of migraine in adolescent population (≥ 12 to <18 years of age) as measured by pain freedom using the number of patients reporting no pain.
Pain freedom will be assessed in adolescent population (≥ 12 to \< 18 years of age) on a 4-point numeric rating scale (0=none, 1=mild, 2=moderate, 3=severe).
2 hours post-dose
النتيجة الثانوية
مقياس النتيجةوصف القياسالإطار الزمني
To compare rimegepant with placebo for pain freedom in children and adolescents combined.
Pain freedom will be assessed in children and adolescents (≥ 6 to \< 18 years of age) using a 4-point numeric rating scale (0=none, 1=mild, 2=moderate, 3=severe). Pain freedom will be assessed in children (\> 6 to \< 12 years of age) using the 5-Face VAS (Face 5 = 'severe pain', Faces 4 and 3 = 'moderate pain', Face 2 = 'mild pain', Face 1 = 'no pain').
2 hours post-dose
To compare rimegepant with placebo on freedom from the most bothersome symptom (MBS) associated with migraine in adolescents.
Freedom from MBS (nausea, phonophobia or photophobia) will be measured using a binary scale (0=absent, 1=present).
2 hours post-dose
To compare rimegepant with placebo on the probabilities of requiring rescue medication within in adolescents.
Use of rescue medication will be assessed using the numbers of participants that take rescue medication.
Within 24 hours and 48 hours of initial treatment
To compare rimegepant with placebo on sustained pain freedom in adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 24 hours post-dose
To compare rimegepant with placebo on sustained pain freedom in adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 48 hours post-dose
To compare rimegepant with placebo on the ability to function normally as reported on the Functional Disability scale in adolescents.
The proportion of participants able to function normally will be assessed using the number that self-report as "normal" on the Functional Disability scale.
2 hours post-dose
To compare rimegepant with placebo for pain freedom in children.
Pain freedom will be assessed using the number of children (≥ 6 to \< 12 years of age) that report no pain measured by a 5-Face VAS (Face 5 = 'severe pain', Faces 4 and 3 = 'moderate pain', Face 2 = 'mild pain', Face 1 = 'no pain').
2 hours post-dose
To compare rimegepant with placebo on freedom from the most bothersome symptom (MBS) associated with migraine in children and combined children and adolescents.
Freedom from the most bothersome symptom (nausea, phonophobia or photophobia) will be assessed using the number of participants that report the absence of MBS measured using a binary scale (0=absent, 1=present).
2 hours post-dose
To compare rimegepant with placebo on the probabilities of requiring rescue medication in children and combined children and adolescents.
The probabilities of requiring rescue medication will be assessed using the numbers of participants that take rescue medication within initial treatment.
Within 24 hours and 48 hours of initial treatment.
To compare rimegepant with placebo on sustained pain freedom in children and combined children and adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 24 hours post-dose
To compare rimegepant with placebo on sustained pain freedom in children and combined children and adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 48 hours post-dose
To compare rimegepant with placebo on freedom from photophobia in adolescents, children and combined children and adolescents.
Freedom from photophobia will be assessed by the number of participants that report the absence of photophobia post dose that reported the presence of photophobia at baseline.
2 hours post-dose
To compare rimegepant with placebo on freedom from phonophobia in adolescents, children and combined children and adolescents.
Freedom from phonophobia will be assessed by the number of participants that report the absence of phonophobia post dose that reported the presence of phonophobia at baseline.
2 hours post-dose
To compare rimegepant with placebo on freedom from nausea in adolescents, children and combined children and adolescents.
Freedom from nausea will be assessed by the number of participants that report the absence of nausea post dose that reported the presence of nausea at baseline.
2 hours post-dose
To compare rimegepant with placebo on pain relief in adolescents, children and combined children and adolescents.
Pain relief will be assessed using the number of participants that report a pain level of moderate or severe at baseline and then report a pain level of none or mild post dose.
2 hours post-dose
To compare rimegepant with placebo in adolescents, children and combined children and adolescents on pain relief.
Time to first report of pain relief will be based on the first time point a participant reports a pain level of none or mild.
Time to patients first report of pain relief of none or mild post dose up to 48 hours.
مساعد المشاركة
معايير الأهلية

الأعمار المؤهلة للدراسة
طفل
العمر الأدنى للدراسة
6 Years
الجنس المؤهل
الكل

  1. History of migraine (with or without aura) for > 6 months before Screening according to the IHS Classification ICHD-319 specifications for pediatric migraine. History may be verified using both medical records and recall by the participant and/or participant's parent(s)/legal representative(s).

  2. History of 1 to 8 moderate or severe attacks per month during the 2 months prior to enrollment, with attacks lasting > 3 hours without treatment, and attacks occurring at intervals > 24 hours.

  3. Prophylactic migraine medication are permitted if the dose has been stable for at least 12 weeks prior to the Baseline Visit, and the dose is not expected to change during the course of the study.

    1. Participants may remain on one (1) medication with possible migraine prophylactic effects, excluding CGRP antagonists \[biologic or small molecule\], during the treatment phases.
    2. Concomitant use of a CGRP antagonist, such as erenumab or fremanezumab, is prohibited.
    3. Previously discontinued prophylactic migraine medication must have done so at least 90 days prior to the Screening Visit.

  4. Verbally distinguish between migraine and other types of headaches.

  5. Participants must have a weight > 40 kg at the Screening Visit.

  6. Adequate venous access for blood sampling.

  7. Male and female participants ≥ 6 to < 18 years of age (participants must not reach their 18th birthday during the study).

  1. History of cluster headache or hemiplegic migraine headache.
  2. Confounding and clinically significant pain syndrome that may interfere with the participant's ability to participate in this study.
  3. Current psychiatric condition that is uncontrolled and/or untreated for a minimum of 6 months prior to the Screening Visit. Participants with a lifetime history of psychosis and/or mania.
  4. History of suicidal behavior or major psychiatric disorder.
  5. Current diagnosis or history of substance abuse; positive drug test at Screening.
  6. History of moderate or severe head trauma or other neurological disorder (including seizure disorder) or systemic medical disease that is likely to affect central nervous system functioning.
  7. Recent or planned surgery, requiring general anesthesia, <8 weeks prior to the Screening Visit.
  8. Participant has had gastrointestinal surgery that interferes with physiological absorption and motility (i.e., gastric bypass, duodenectomy, or gastric banding).
  9. Current diagnosis of viral hepatitis or a history of liver disease.
  10. Conditions considered clinically relevant in the context of the study such as uncontrolled hypertension (high blood pressure), diabetes, a life-threatening allergy
Pfizer logoفايزر457 تجارب سريرية نشطة للاستكشاف
جهة اتصال مركزية للدراسة
جهة اتصال: Pfizer Pfizer CT.gov Call Center, 1-800-718-1021, [email protected]
245 مواقع الدراسة في 9 بلدان

Alabama

Achieve Clinical Research, LLC d/b/a Accel Research Sites-Neurology and Neurodiagnostic of Alabama, Birmingham, Alabama, 35244, United States
نشط (لا يقبل مشاركين جدد)

Arizona

Perseverance Research Center, LLC, Scottsdale, Arizona, 85253, United States
يقبل مشاركين
Physicians Research Group, Tempe, Arizona, 85284, United States
نشط (لا يقبل مشاركين جدد)

California

Advanced Research Center, Inc., Anaheim, California, 92805, United States
يقبل مشاركين
Adult & Child Neurology Medical Associates, Costa Mesa, California, 92627, United States
يقبل مشاركين
ProScience Research Group, Culver City, California, 90230, United States
يقبل مشاركين
Memorial Health Services, Fountain Valley, California, 92708, United States
يقبل مشاركين
Neuro-Pain Medical Center, Fresno, California, 93710, United States
يقبل مشاركين
Regents of the University of California (UC San Diego), La Jolla, California, 92093, United States
يقبل مشاركين
Adult & Child Neurology Medical Associates, Long Beach, California, 90806, United States
يقبل مشاركين
Miller Children's & Women's Hospital Long Beach, Long Beach, California, 90806, United States
يقبل مشاركين
National Research Institute, Los Angeles, California, 90057, United States
نشط (لا يقبل مشاركين جدد)
Velocity Clinical Research - North Hollywood, North Hollywood, California, 91606, United States
نشط (لا يقبل مشاركين جدد)
Children's Hospital of Orange County - Inpatient Pharmacy, Orange, California, 92868, United States
لم يبدأ القبول بعد
Children's Hospital of Orange County - Neuroscience Center, Orange, California, 92868, United States
لم يبدأ القبول بعد
Children's Hospital of Orange County, Orange, California, 92868, United States
لم يبدأ القبول بعد
The Neurology Group, Pomona, California, 91767, United States
يقبل مشاركين
University of California, Davis Midtown Clinic, Sacramento, California, 95816, United States
نشط (لا يقبل مشاركين جدد)
UC Davis Medical Center, Investigational Drug Service (IDS) Pharmacy, Sacramento, California, 95817, United States
نشط (لا يقبل مشاركين جدد)
University of California, Davis Clinical and Translational Science Center Clinical Research (CCRC), Sacramento, California, 95817, United States
نشط (لا يقبل مشاركين جدد)
Velocity Clinical Research, San Bernardino (IP Delivery and Administering Location), San Bernardino, California, 92408, United States
يقبل مشاركين
Pacific Clinical Research Management Group LLC, Upland, California, 91786, United States
نشط (لا يقبل مشاركين جدد)
Sunwise Clinical Research, Walnut Creek, California, 94596, United States
يقبل مشاركين

Colorado

Children's Hospital Colorado- lnvestigational Drug Services, Aurora, Colorado, 80045, United States
يقبل مشاركين
Children's Hospital Colorado, Aurora, Colorado, 80045, United States
يقبل مشاركين
Colorado Springs Neurological Associates, PC, Colorado Springs, Colorado, 80907, United States
يقبل مشاركين
Colorado Springs Neurological Associates, PC, Colorado Springs, Colorado, 80919, United States
يقبل مشاركين

Connecticut

CT Clinical Research, Cromwell, Connecticut, 06416, United States
يقبل مشاركين
Connecticut Children's Medical Center, Hartford, Connecticut, 06106, United States
نشط (لا يقبل مشاركين جدد)
Ki Health Partners, LLc, dba New England Institute for Clinical Research, Stamford, Connecticut, 06905, United States
يقبل مشاركين

Delaware

Nemours Children's Hospital, Delaware, Wilmington, Delaware, 19803, United States
نشط (لا يقبل مشاركين جدد)

District of Columbia

Children's National Medical Center, Washington D.C., District of Columbia, 20010, United States
يقبل مشاركين

Florida

Topaz Clinical Research, Inc., Apopka, Florida, 32703, United States
نشط (لا يقبل مشاركين جدد)
Beautiful Minds Clinical Research Center, Cutler Bay, Florida, 33157, United States
متوقف نهائيًا
DeLand Clinical Research Unit, DeLand, Florida, 32720, United States
متوقف نهائيًا
Sarkis Clinical Trials, Gainesville, Florida, 32607, United States
نشط (لا يقبل مشاركين جدد)
Multi-Specialty Research Associates, Inc., Lake City, Florida, 32055, United States
نشط (لا يقبل مشاركين جدد)
Watson Clinic Center for Research, Inc., Lakeland, Florida, 33805, United States
متوقف نهائيًا
Watson Clinic LLP, Lakeland, Florida, 33805, United States
متوقف نهائيًا
AppleMed Research Group, LLC, Miami, Florida, 33126, United States
يقبل مشاركين
Medical Research Center of Miami II, Inc, Miami, Florida, 33134, United States
نشط (لا يقبل مشاركين جدد)
Nicklaus Children's Hospital, Research Institute, Miami, Florida, 33155, United States
لم يبدأ القبول بعد
South Florida Research Phase I-IV, Inc, Miami, Florida, 33166, United States
يقبل مشاركين
Brainstorm Research, Miami, Florida, 33176, United States
نشط (لا يقبل مشاركين جدد)
Advanced Research for Health Improvement, LLC/ Dr. Cordero's Pediatric Office, Naples, Florida, 34102, United States
نشط (لا يقبل مشاركين جدد)
Aqualane Clinical Research, Naples, Florida, 34105, United States
يقبل مشاركين
Coastal Clinical Research Specialists, Orange Park, Florida, 32073, United States
نشط (لا يقبل مشاركين جدد)
Clinical Associates of Orlando, LLC, Orlando, Florida, 32819, United States
يقبل مشاركين
Bioresearch Institute, Pembroke Pines, Florida, 33026, United States
متوقف نهائيًا
Forcare Clinical Research, Tampa, Florida, 33613, United States
يقبل مشاركين
Premiere Research Institute at Palm Beach Neurology, West Palm Beach, Florida, 33407, United States
نشط (لا يقبل مشاركين جدد)

Georgia

Children's Healthcare of Atlanta, Inc., Atlanta, Georgia, 30329, United States
يقبل مشاركين
Childrens Healthcare of Atlanta, Atlanta, Georgia, 30329, United States
يقبل مشاركين
Rare Disease Research, LLC, Atlanta, Georgia, 30329, United States
نشط (لا يقبل مشاركين جدد)
Pivotal Clinical Research & Associates, LLC, Brunswick, Georgia, 31520, United States
يقبل مشاركين
CenExel iResearch, LLC, Decatur, Georgia, 30030, United States
يقبل مشاركين

Illinois

Chicago Headache Center & Research Institute, Chicago, Illinois, 60657, United States
يقبل مشاركين
AMR-Baber Research Inc, Naperville, Illinois, 60563, United States
يقبل مشاركين

Indiana

Options Research Group, LLC, Westfield, Indiana, 46074, United States
يقبل مشاركين

Iowa

Velocity Clinical Research, Sioux City, Sioux City, Iowa, 51106, United States
يقبل مشاركين
Integrated Clinical Trial Services, West Des Moines, Iowa, 50265, United States
يقبل مشاركين

Kansas

Clinical Associates Midwest, LLC, Kansas City, Kansas, 66214, United States
يقبل مشاركين
College Park Family Care Center Physicians Group- Neurology Research Dept., Overland Park, Kansas, 66212, United States
نشط (لا يقبل مشاركين جدد)

Kentucky

Kentucky Neuroscience Institute Child Neurology-- "Patients Seen", Lexington, Kentucky, 40504, United States
نشط (لا يقبل مشاركين جدد)
UK Center for Clinical and Translational Science (CCTS) -- "Patients Seen", Lexington, Kentucky, 40536, United States
نشط (لا يقبل مشاركين جدد)
University of Kentucky Hospital, Lexington, Kentucky, 40536, United States
نشط (لا يقبل مشاركين جدد)

Louisiana

Ochsner Clinic Foundation, New Orleans, Louisiana, 70121, United States
نشط (لا يقبل مشاركين جدد)
Neurology and Headache Center, Inc., Shreveport, Louisiana, 71105, United States
نشط (لا يقبل مشاركين جدد)

Massachusetts

Boston Clinical Trials, Boston, Massachusetts, 02131, United States
نشط (لا يقبل مشاركين جدد)
MedVadis Research Corporation, Waltham, Massachusetts, 02451, United States
نشط (لا يقبل مشاركين جدد)

Michigan

Michigan Head Pain & Neurological Institute, Ann Arbor, Michigan, 48104, United States
يقبل مشاركين
Corewell Health, for and on behalf of Spectrum Health Hospital and Corewell Health Medical Group, Grand Rapids, Michigan, 49503, United States
يقبل مشاركين
Corewell Health, Helen DeVos Children's Hospital, Grand Rapids, Michigan, 49503, United States
يقبل مشاركين
Wellnow Urgent Care and Research, Kalamazoo, Michigan, 49048, United States
نشط (لا يقبل مشاركين جدد)
Beaumont Hospital Royal Oak Campus, Royal Oak, Michigan, 48073, United States
يقبل مشاركين

Minnesota

Brackenridge Outpatient Research Pharmacy, Rochester, Minnesota, 55905, United States
يقبل مشاركين
Clinical Research Trials Unit, Rochester, Minnesota, 55905, United States
يقبل مشاركين
Mayo Clinic, Rochester, Minnesota, 55905, United States
يقبل مشاركين

Mississippi

Precise Research Centers, Flowood, Mississippi, 39232, United States
يقبل مشاركين

Missouri

Sharlin Health Neuroscience Research Center, Ozark, Missouri, 65721, United States
يقبل مشاركين
Clinvest Research, LLC, Springfield, Missouri, 65810, United States
نشط (لا يقبل مشاركين جدد)

Montana

Boeson Research, Great Falls, Montana, 59405, United States
يقبل مشاركين
Boeson Research, Kalispell, Montana, 59901, United States
نشط (لا يقبل مشاركين جدد)
Heart & Hands Midwifery, Kalispell, Montana, 59901, United States
نشط (لا يقبل مشاركين جدد)
Blue Moose Pediatrics, Missoula, Montana, 59804, United States
يقبل مشاركين
Boeson Research Laboratory, Missoula, Montana, 59804, United States
يقبل مشاركين
Boeson Research, Missoula, Montana, 59804, United States
يقبل مشاركين

Nebraska

Alivation Research, LLC., Lincoln, Nebraska, 68526, United States
متوقف نهائيًا
Children's Hospital & Medical Center, Omaha, Nebraska, 68114, United States
يقبل مشاركين

New Jersey

HMH Jersey Shore University Medical Center, Neptune City, New Jersey, 07753, United States
يقبل مشاركين

New York

Dent Neurosciences Research Center, Amherst, New York, 14226, United States
يقبل مشاركين
True North Neurology, Commack, New York, 11725, United States
يقبل مشاركين
Northwell Health/ Division of Pediatric Neurology, Lake Success, New York, 11042, United States
يقبل مشاركين
NYU Langone Hospital-Long Island, Clinical Research Center, Mineola, New York, 11501, United States
نشط (لا يقبل مشاركين جدد)
NYU Langone Hospital-Long Island, Pediatric Neurology, Mineola, New York, 11501, United States
نشط (لا يقبل مشاركين جدد)
New York Neurology Associates, New York, New York, 10003, United States
يقبل مشاركين
Weill Cornell Medicine, New York, New York, 10021, United States
يقبل مشاركين
Mount Sinai Hospital - Pharmacy Department, New York, New York, 10029, United States
نشط (لا يقبل مشاركين جدد)
Columbia University Medical Center Research Pharmacy, New York, New York, 10032, United States
نشط (لا يقبل مشاركين جدد)
Columbia University Pediatric Neuromuscular Center, New York, New York, 10032, United States
نشط (لا يقبل مشاركين جدد)
Irving Center for Clinical and Translational Research, Outpatient Clinical Research Unit, New York, New York, 10032, United States
نشط (لا يقبل مشاركين جدد)
The Neurological Institute of New York, New York, New York, 10032, United States
نشط (لا يقبل مشاركين جدد)
The Trustees of Columbia University and The New York and Presbyterian Hospital, New York, New York, 10032, United States
نشط (لا يقبل مشاركين جدد)
North Suffolk Neurology P.C, Port Jefferson Station, New York, 11776, United States
نشط (لا يقبل مشاركين جدد)
Finger Lakes Clinical Research, Rochester, New York, 14618, United States
متوقف نهائيًا
Prime Global Research, LLC, The Bronx, New York, 10456, United States
متوقف نهائيًا

North Carolina

New Hope Clinical Research, Charlotte, North Carolina, 28211, United States
نشط (لا يقبل مشاركين جدد)
OnSite Clinical Solutions, LLC, Charlotte, North Carolina, 28277, United States
يقبل مشاركين
Velocity Clinical Research, Inc., Durham, North Carolina, 27701, United States
يقبل مشاركين
Headache Wellness Center, PC, Greensboro, North Carolina, 27405, United States
يقبل مشاركين

Ohio

Akron Children's Hospital, Akron, Ohio, 44308, United States
يقبل مشاركين
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229, United States
يقبل مشاركين
Velocity Clinical Research, Cincinnati, Ohio, 45242, United States
يقبل مشاركين
University Hospitals Cleveland Medical Center, Cleveland, Ohio, 44106, United States
يقبل مشاركين
Nationwide Children's Hospital, Columbus, Ohio, 43205, United States
نشط (لا يقبل مشاركين جدد)
Wellnow Urgent Care and Research, Columbus, Ohio, 43228, United States
نشط (لا يقبل مشاركين جدد)
Neuro-Behavioral Clinical Research, Inc., North Canton, Ohio, 44720, United States
نشط (لا يقبل مشاركين جدد)

Oklahoma

IPS Research Company, Oklahoma City, Oklahoma, 73106, United States
نشط (لا يقبل مشاركين جدد)
Lynn Institute of Tulsa, Tulsa, Oklahoma, 74135, United States
نشط (لا يقبل مشاركين جدد)

Oregon

Velocity Clinical Research, Grants Pass, Grants Pass, Oregon, 97527, United States
نشط (لا يقبل مشاركين جدد)
Providence Health & Services Investigational Drug Services Westside, Portland, Oregon, 97225, United States
يقبل مشاركين
Providence Neuroscience Institute - Research Coordinator's Office, Portland, Oregon, 97225, United States
يقبل مشاركين
Providence Pediatric Neurology, Portland, Oregon, 97225, United States
يقبل مشاركين
Providence St. Vincent Medical Center, Portland, Oregon, 97225, United States
يقبل مشاركين

Pennsylvania

Clario, Philadelphia, Pennsylvania, 19103, United States
يقبل مشاركين
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United States
نشط (لا يقبل مشاركين جدد)

Rhode Island

Velocity Clinical Research-Providence, East Greenwich, Rhode Island, 02818, United States
يقبل مشاركين

South Carolina

Premier Neurology, PC, Greenville, South Carolina, 29605, United States
نشط (لا يقبل مشاركين جدد)
Tribe Clinical Research, LLC, Greenville, South Carolina, 29607, United States
نشط (لا يقبل مشاركين جدد)
Velocity Clinical Research - Greenville, Greenville, South Carolina, 29615, United States
نشط (لا يقبل مشاركين جدد)

Tennessee

Holston Medical Group., Kingsport, Tennessee, 37660, United States
نشط (لا يقبل مشاركين جدد)
Holston Medical Group, Kingsport, Tennessee, 37660, United States
نشط (لا يقبل مشاركين جدد)
Le Bonheur Children's Hospital - Outpatient Building, Memphis, Tennessee, 38103, United States
يقبل مشاركين
Le Bonheur Children's Hospital, Memphis, Tennessee, 38103, United States
يقبل مشاركين
Le Bonheur Childrens Hospital - Childrens Foundation Research Institute, Memphis, Tennessee, 38103, United States
يقبل مشاركين
Access Clinical Trials, Inc., Nashville, Tennessee, 37203, United States
نشط (لا يقبل مشاركين جدد)

Texas

Dell Children's Medical Center, Austin, Texas, 78723, United States
يقبل مشاركين
Child Neurology Consultants of Austin - South Austin, Austin, Texas, 78749, United States
يقبل مشاركين
Child Neurology Consultants of Austin - Central Austin, Austin, Texas, 78757, United States
يقبل مشاركين
BioBehavioral Research of Austin, Austin, Texas, 78759, United States
نشط (لا يقبل مشاركين جدد)
Houston Clinical Trials, LLC, Bellaire, Texas, 77401, United States
يقبل مشاركين
Infinite Research Group, LLC, Dallas, Texas, 75201, United States
يقبل مشاركين
Children's Medical Center, Dallas, Dallas, Texas, 75235, United States
يقبل مشاركين
Children's Medical Center, Pediatric Anesthesiology Research (Study supplies only), Dallas, Texas, 75235, United States
يقبل مشاركين
Cedar Health Research, Dallas, Texas, 75251, United States
يقبل مشاركين
FutureSearch Trials of Dallas, LLC, Dallas, Texas, 75251, United States
يقبل مشاركين
The University of Texas Southwestern Medical Center, Dallas, Texas, 75390, United States
يقبل مشاركين
ANESC Research, El Paso, Texas, 79912, United States
يقبل مشاركين
North Texas Institute of Neurology and Headache, Frisco, Texas, 75034, United States
نشط (لا يقبل مشاركين جدد)
UTHealth Houston, Houston, Texas, 77030, United States
يقبل مشاركين
Pain and Headache Centers of Texas, Houston, Texas, 77054, United States
يقبل مشاركين
SCLA Management, Houston, Texas, 77077, United States
يقبل مشاركين
Houston Clinical Research,LLC., Houston, Texas, 77081, United States
نشط (لا يقبل مشاركين جدد)
NeuroCare Plus, Houston, Texas, 77094, United States
يقبل مشاركين
AIM Trials, LLC, Plano, Texas, 75093, United States
يقبل مشاركين

Utah

JBR Clinical Research, Salt Lake City, Utah, 84107, United States
يقبل مشاركين
Wasatch Clinical Research , LLC(Administrative Location), Salt Lake City, Utah, 84107, United States
يقبل مشاركين

Vermont

The University of Vermont Medical Center, Burlington, Vermont, 05401, United States
نشط (لا يقبل مشاركين جدد)

Virginia

Pediatric Research of Charlottesville, LLC (Regulatory Only), Charlottesville, Virginia, 22902, United States
يقبل مشاركين
Pediatric Research of Charlottesville, LLC, Charlottesville, Virginia, 22902, United States
يقبل مشاركين
Children's Hospital of the King's Daughters, Norfolk, Virginia, 23507, United States
يقبل مشاركين
Children's Specialty Group, PLLC, Norfolk, Virginia, 23507, United States
يقبل مشاركين
Children's Specialty Group, PLLC, Division of Childhood & Adolescent Neurology, Norfolk, Virginia, 23510, United States
يقبل مشاركين
National Clinical Research, Inc., Richmond, Virginia, 23294, United States
نشط (لا يقبل مشاركين جدد)

Washington

Northwest Clinical Research Center, Bellevue, Washington, 98007, United States
يقبل مشاركين
Eastside Therapeutic Resource, Inc. dba Core Clinical Research, Everett, Washington, 98201, United States
نشط (لا يقبل مشاركين جدد)
Seattle Children's Hospital Investigational Drug Services, Seattle, Washington, 98105, United States
يقبل مشاركين
Seattle Children's Hospital, Seattle, Washington, 98105, United States
يقبل مشاركين

Wisconsin

Clinical Investigation Specialists, Inc, Kenosha, Wisconsin, 53144, United States
يقبل مشاركين
University Hospital, Madison, Wisconsin, 53792, United States
يقبل مشاركين

British Columbia

OCT Research ULC, Kelowna, British Columbia, V1Y 1Z9, Canada
يقبل مشاركين

Quebec

Diex Recherche Sherbrooke Inc, Sherbrooke, Quebec, J1L 0H8, Canada
نشط (لا يقبل مشاركين جدد)

Anhui

First Affiliated Hospital of Bengbu Medical College Neurology, Bengbu, Anhui, 233000, China
يقبل مشاركين
Anhui Provincial Hospital, Hefei, Anhui, 230000, China
يقبل مشاركين

Beijing Municipality

Chinese PLA General Hospital, Beijing, Beijing Municipality, 100089, China
يقبل مشاركين

Chongqing Municipality

" The First Affiliated Hospital of Chongqing Medical University", Chongqing, Chongqing Municipality, 400042, China
يقبل مشاركين

Gansu

Lanzhou university second hospital, Lanzhou, Gansu, 730030, China
يقبل مشاركين

Guangdong

Shenzhen Children's Hospital, Shenzhen, Guangdong, 518034, China
يقبل مشاركين

Hainan

Hainan General Hospital, Haikou, Hainan, 571140, China
يقبل مشاركين

Hebei

The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, China
يقبل مشاركين
The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050004, China
يقبل مشاركين

Henan

People's Hospital of Zhengzhou, Zhengzhou, Henan, 450000, China
يقبل مشاركين

Hubei

Jingzhou First People's Hospital, Jingzhou, Hubei, 434000, China
يقبل مشاركين
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China
يقبل مشاركين
Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
يقبل مشاركين

Hunan

The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410000, China
يقبل مشاركين
Hunan Children's Hospital, Changsha, Hunan, 410007, China
يقبل مشاركين
The Third Xiangya Hospital of Central South University, Changsha, Hunan, 410013, China
يقبل مشاركين

Jiangsu

The Second People's Hospital of Lianyungang, Lianyungang, Jiangsu, 222002, China
يقبل مشاركين
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China
يقبل مشاركين
Wuxi Children's Hospital, Wuxi, Jiangsu, 214023, China
يقبل مشاركين
Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214115, China
يقبل مشاركين
Xuzhou Children's Hospital, Xuzhou, Jiangsu, 221002, China
يقبل مشاركين
Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, China
يقبل مشاركين

Jilin

The First Hospital of Jilin University, Pediatric Neurology, Changchun, Jilin, 130021, China
يقبل مشاركين

Ningxia

General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 756000, China
يقبل مشاركين

Shaanxi

Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China
يقبل مشاركين
Xi'an Gaoxin Hospital Neurology Department, Xi'an, Shaanxi, 710075, China
يقبل مشاركين
Yan 'an University Xianyang Hospital, Xianyang, Shaanxi, 716000, China
يقبل مشاركين

Shandong

Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, 250013, China
يقبل مشاركين
Liaocheng People's Hospital, Liaocheng, Shandong, 252000, China
يقبل مشاركين

Sichuan

West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, China
يقبل مشاركين

Zhejiang

Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310052, China
يقبل مشاركين
Ningbo Women and Children's Hospital, Ningbo, Zhejiang, 315012, China
يقبل مشاركين
The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China
يقبل مشاركين
Lu 'an People's Hospital, Lu'an, China
يقبل مشاركين
Children's Hospital of Shanghai, Shanghai, China
يقبل مشاركين
Shengjing Hospital of China Medical University, Shenyang, China
يقبل مشاركين
The First Affiliated Hospital of Shihezi University School of Medicine, Shihezi, China
نشط (لا يقبل مشاركين جدد)
Wuhan Children's Hospital, Wuhan, China
يقبل مشاركين

Fukuoka

Jinnouchi Neurosurgical Clinic, Kasuga-shi, Fukuoka, 816-0802, Japan
يقبل مشاركين
Ikeda Neurosurgical Clinic, Kasuga-shi, Fukuoka, 816-0824, Japan
يقبل مشاركين

Gunma

Hikita Pediatric Clinic, Kiryu-shi, Gunma, 3760035, Japan
يقبل مشاركين

Hyōgo

Konan Medical Center, Higashinada-ku Kobe-shi, Hyōgo, 658-0064, Japan
يقبل مشاركين
Yamaguchi Clinic, Nishinomiya-shi, Hyōgo, 663-8204, Japan
يقبل مشاركين

Ibaraki

Mito Kyodo General Hospital, Mito, Ibaraki, 310-0015, Japan
يقبل مشاركين

Kagoshima-ken

Tanaka Neurosurgery & Headache Clinic, Kagoshima, Kagoshima-ken, 890-0052, Japan
يقبل مشاركين

Miyagi

Sendai Headache and Neurology Clinic, Taihaku-ku Sendai-shi, Miyagi, 982-0014, Japan
يقبل مشاركين

Osaka

Tennoji Dai Brain Clinic, Abeno-ku Osaka-shi, Osaka, 545-0053, Japan
يقبل مشاركين
Tominaga Clinic, Naniwa-ku, Osaka, 556-0015, Japan
يقبل مشاركين

Tokyo

Tokyo Headache Clinic, Shibuya-ku, Tokyo, 151-0051, Japan
يقبل مشاركين
Tokyo Medical University Hospital, Shinjuku-ku, Tokyo, 160-0023, Japan
لم يبدأ القبول بعد
Local lndependent Administrative Corporation Hiroshima City Hospital Organization Hiroshima City, Hiroshima, 730-8518, Japan
يقبل مشاركين

Mexico City

Clinstile S.A. de C.V., Col. Roma Norte, Mexico City, C.P. 06700., Mexico
يقبل مشاركين

Sinaloa

Neurociencias Estudios Clinicos S.C., Culiacán, Sinaloa, 800200, Mexico
يقبل مشاركين

State of Mexico

Clinical Reseach Institute, S.C., Tlalnepantla, State of Mexico, C.P. 54055, Mexico
يقبل مشاركين
Unidad de Investigacion en Salud de Chihuahua S.C., Chihuahua City, 31203, Mexico
يقبل مشاركين

Lower Silesian Voivodeship

MIGRE Polskie Centrum Leczenia Migreny Anna Gryglas-Dworak, Wroclaw, Lower Silesian Voivodeship, 52-210, Poland
يقبل مشاركين
NZOZ Wielospecjalistyczna Poradnia Lekarska SYNAPSIS, Lech Szczechowski, Katowice, 40-123, Poland
نشط (لا يقبل مشاركين جدد)
Centrum Medyczne Plejady, Krakow, 30-363, Poland
يقبل مشاركين
Wojewódzki Specjalistyczny Szpital Dzieciecy im. Sw. Ludwika w Krakowie, Apteka Szpitalna, Krakow, 31-503, Poland
يقبل مشاركين
Clinical Research Center Sp. z.o.o. Medic-R Spolka komandytowa, Poznan, 61-731, Poland
يقبل مشاركين
Euromedis Sp. z o. o., Szczecin, 70-111, Poland
نشط (لا يقبل مشاركين جدد)

Cantabria

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, 39008, Spain
نشط (لا يقبل مشاركين جدد)
Hospital Universitario Vall d'Hebron, Barcelona, 08035, Spain
يقبل مشاركين
Centre d'Atencio Primaria Balenya, Barcelona, 08550, Spain
نشط (لا يقبل مشاركين جدد)
Instituto de Investigaciones del Sueno, Madrid, 28036, Spain
نشط (لا يقبل مشاركين جدد)
Hospital Universitario Virgen del Rocío, Seville, 41013, Spain
يقبل مشاركين
Hospital Clinico Universitario de Valladolid, Valladolid, 47005, Spain
يقبل مشاركين

Skåne LÄN [se-12]

ProbarE i Lund AB, Lund, Skåne LÄN [se-12], 22222, Sweden
يقبل مشاركين
Avdelningen för kliniska Prövningar, Universitetssjukhuset Örebro, Örebro, 703 62, Sweden
نشط (لا يقبل مشاركين جدد)
ProbarE i Stockholm AB, Stockholm, 113 29, Sweden
يقبل مشاركين
Leicester Royal Infirmary, Leicester, LE1 5WW, United Kingdom
نشط (لا يقبل مشاركين جدد)
Re:Cognition Health Limited, London, W1G 9JF, United Kingdom
يقبل مشاركين
Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, United Kingdom
يقبل مشاركين