رادار التجارب AI | ||
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حالة التجربة السريرية NCT07175948 (PED-MYO) لـ التهاب عضلة القلب، التهاب عضلة القلب الحاد هي لم يبدأ القبول بعد. اطلعوا على جميع التفاصيل في عرض البطاقة الخاص برادار التجارب السريرية وأدوات اكتشاف الذكاء الاصطناعي. أو يمكنكم طرح أي سؤال هنا. | ||
تجربة واحدة تطابق معايير الفلتر
عرض البطاقة
العودة إلى البحث
جامعة أسيوطOutcome of Clinical Phenotypes of Pediatric Myocarditis at Assiut University Children Hospital (PED-MYO) ١٠٠ موجه بالمؤشرات الحيوية طب الأطفال
تفاصيل التجربة السريرية متاحة بشكل أساسي باللغة الإنجليزية. ومع ذلك، يمكن لـ رادار التجارب AI مساعدتك؛ ما عليك سوى النقر على «وصف الدراسة» لعرض ومناقشة معلومات التجربة باللغة التي اخترتها.
التجربة السريرية NCT07175948 (PED-MYO) هي دراسة رصدية لـالتهاب عضلة القلب، التهاب عضلة القلب الحاد وهي لم يبدأ القبول بعد. من المقرر أن يبدأ التسجيل في ١٥ ذو الحجة ١٤٤٧ هـ لتجنيد ١٠٠ مشاركًا. يقودها جامعة أسيوط، ومن المتوقع اكتمالها بحلول ٢٨ صفر ١٤٤٩ هـ. تم تحديث البيانات الأخيرة من ClinicalTrials.gov في ٢٤ ربيع الأول ١٤٤٧ هـ.
الملخص
This study aims to investigate the clinical phenotypes, management approaches, and outcomes of myocarditis in children admitted to Assiut University Children's Hospital. Myocarditis is an inflammatory disease of the heart muscle that can present in different clinical forms, including acute, fulminant, chronic active, and chronic persistent types. These forms vary in severity, treatment needs, and long-term outcomes.
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وصف مفصل
Myocarditis is an inflammatory disorder of the myocardium that may cause myocyte injury, necrosis, and cardiac dysfunction. Pediatric myocarditis has heterogeneous clinical phenotypes, commonly categorized into acute, fulminant, chronic active, and chronic persistent forms. These categories differ in pathophysiology, clinical presentation, and prognosis, making phenotypic classification essential for guiding treatmen...عرض المزيد
العنوان الرسمي
Outcome of Different Clinical Phenotypes of Myocarditis in Children Admitted to Assiut University Children Hospital
الحالات الطبية
التهاب عضلة القلبالتهاب عضلة القلب الحادالمنشورات
مقالات علمية وأوراق بحثية منشورة حول هذه التجربة السريرية:معرّفات دراسة أخرى
- PED-MYO
- AUMCH-MYO-2025
NCT معرّف
تاريخ البدء (فعلي)
2026-06-01
آخر تحديث مُنشور
2025-09-16
تاريخ الاكتمال (المقدر)
2027-08-01
عدد المشاركين المخطط لهم
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نوع الدراسة
رصدية
الحالة
لم يبدأ القبول بعد
الكلمات الرئيسية
Viral Myocarditis
Cardiogenic Shock
Cardiogenic Shock
مجموعات/التدخلات
| مجموعة المشاركين/الذراع | التدخل/العلاج |
|---|---|
Acute Myocarditis Children (1-18 years) diagnosed with acute myocarditis, typically following viral illness, presenting with fever, chest pain, heart failure symptoms, or arrhythmias. Diagnosis supported by elevated cardiac biomarkers, echocardiographic findings of LV dysfunction, and ECG changes. Management includes standard medical therapy (inotropes, ACE inhibitors, beta-blockers) and in some cases corticosteroids or IVIG depending...عرض المزيد | العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (e.g., dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Treatment is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status. The goal is to stabilize heart failure, improve cardiac output, and prevent progression to dilated...عرض المزيد العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Therapy is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status to stabilize heart failure, improve cardiac output, and prevent progression to dilated cardiomyopathy.
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Fulminant Myocarditis Children presenting with sudden, severe myocarditis characterized by rapid onset of cardiogenic shock, severe LV dysfunction, or multi-organ involvement. Diagnosis based on clinical picture, elevated biomarkers, echocardiography, and ECG. Management frequently requires intensive care, high-dose inotropes, and may include IVIG, corticosteroids, and mechanical circulatory support such as ECMO if indicated. | العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (e.g., dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Treatment is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status. The goal is to stabilize heart failure, improve cardiac output, and prevent progression to dilated...عرض المزيد العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Therapy is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status to stabilize heart failure, improve cardiac output, and prevent progression to dilated cardiomyopathy.
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Chronic Active Myocarditis Children with ongoing inflammatory myocarditis lasting weeks to months, presenting with persistent heart failure symptoms, arrhythmias, or progressive LV dysfunction. Diagnosis confirmed by echo and biomarkers, sometimes MRI. Treatment includes standard therapy for heart failure plus immunomodulation with corticosteroids and/or IVIG in selected cases. Close monitoring is required to prevent progression. | العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (e.g., dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Treatment is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status. The goal is to stabilize heart failure, improve cardiac output, and prevent progression to dilated...عرض المزيد العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Therapy is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status to stabilize heart failure, improve cardiac output, and prevent progression to dilated cardiomyopathy.
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Chronic Persistent Myocarditis Children with a long-term, indolent course of myocarditis, often progressing toward dilated cardiomyopathy. Patients present with signs of chronic heart failure, reduced EF, and persistent LV dilation. Management includes conventional heart failure therapy (ACE inhibitors, beta-blockers, diuretics, inotropes as needed). Corticosteroids or IVIG may be used in selected patients based on clinical status. Long-term follo...عرض المزيد | العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (e.g., dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Treatment is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status. The goal is to stabilize heart failure, improve cardiac output, and prevent progression to dilated...عرض المزيد العلاج الطبي القياسي All enrolled children will receive standard medical therapy tailored to clinical status. This includes inotropes (dopamine, dobutamine, milrinone), ACE inhibitors, beta-blockers, and/or diuretics as indicated. Therapy is supportive and adjusted according to severity of cardiac dysfunction and hemodynamic status to stabilize heart failure, improve cardiac output, and prevent progression to dilated cardiomyopathy.
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النتيجة الرئيسية
| مقياس النتيجة | وصف القياس | الإطار الزمني |
|---|---|---|
Classification of clinical phenotypes of myocarditis in children | Phenotypic classification (acute, fulminant, chronic active, chronic persistent) will be assigned based on clinical presentation, echocardiography, cardiac biomarkers, and ECG/MRI findings. | At baseline (study enrollment, within first hospital visit). |
Classification of clinical phenotypes of myocarditis in children | Phenotypic classification (acute, fulminant, chronic active, chronic persistent) will be assigned based on clinical presentation, echocardiography, cardiac biomarkers, and ECG/MRI findings. | At baseline (upon parental enrollment, assessed once at study start). |
مساعد المشاركة
معايير الأهلية
الأعمار المؤهلة للدراسة
طفل, بالغ
العمر الأدنى للدراسة
1 Year
الجنس المؤهل
الكل
• Children aged between 1 to 18 years.
- Children diagnosed with myocarditis based on clinical presentation, echocardiography, and cardiac biomarkers, ECG and MRI (if available)
• Children with congenital heart disease.
- Known cardiomyopathy unrelated to myocarditis.
جامعة أسيوط1409 تجارب سريرية نشطة للاستكشافالجهة المسؤولة عن الدراسة
Elshymaa Abdelmged Abdelmenaem, المحقق الرئيسي, resident , pediatric department, Assiut University
جهة اتصال مركزية للدراسة
جهة اتصال: Dr. Elshymaa Abdelmged Abdelmenaem, resident, 01022507912, [email protected]
لا توجد بيانات موقع.