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Die klinische Studie NCT04649242 für Pediatric Migraine ist offene rekrutierung. In der Kartenansicht des Klinische Studien Radar und den KI-Entdeckungstools finden Sie alle Details. Oder stellen Sie hier Ihre Fragen.
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Randomized Study in Children and Adolescents With Migraine: Acute Treatment Phase 3 2.100 Randomisiert Jugendliche

Offene Rekrutierung
Die Details der klinischen Studie sind hauptsächlich auf Englisch verfügbar. Trial Radar KI kann jedoch helfen! Klicken Sie einfach auf 'Studie erklären', um die Informationen zur Studie in der ausgewählten Sprache anzuzeigen und zu besprechen.
Die klinische Studie NCT04649242 untersucht Behandlung im Zusammenhang mit Pediatric Migraine. Diese interventionsstudie der Phase 3 hat den Status offene rekrutierung und startete am 15. Januar 2021. Es ist geplant, 2.100 Teilnehmer aufzunehmen. Durchgeführt von Pfizer wird der Abschluss für 9. Januar 2029 erwartet. Die Daten von ClinicalTrials.gov wurden zuletzt am 20. März 2026 aktualisiert.
Kurzbeschreibung
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
Offizieller Titel

Phase 3, Multicenter, Randomized, Double-blind, Group Sequential, Placebo-controlled Study to Assess Efficacy and Safety of Rimegepant for the Treatment of Migraine (With or Without Aura) in Children and Adolescents ≥ 6 to < 18 Years of Age

Erkrankungen
Pediatric Migraine
Weitere Studien-IDs
  • BHV3000-311
  • C4951002 (Andere Kennung) (Alias Study Number)
  • 2020-003517-35 (Registerkennung) (CTIS (EU))
  • 2024-512743-23-00 (Registerkennung) (CTIS (EU))
NCT-Nummer
NCT04649242
Studienbeginn (tatsächlich)
2021-01-15
Zuletzt aktualisiert
2026-03-20
Studienende (vorauss.)
2029-01-09
Geplante Rekrutierung
2.100
Studientyp
Interventionsstudie
PHASE
Phase 3
Status
Offene Rekrutierung
Stichwörter
Migraine
Acute treatment
Phonophobia
Photophobia
Nausea
Pediatric
Children
Adolescent
Pediatric Migraine
Primäres Ziel
Behandlung
Zuteilungsmethode
Randomisiert
Interventionsmodell
Sequentiell
Verblindung
Dreifach verblindet
Studienarme/Interventionen
Teilnehmergruppe/StudienarmIntervention/Behandlung
Aktives VergleichspräparatBHV3000 (active drug)
BHV3000 (rimegepant) 75 mg or 50 mg ODT
Rimegepant/BHV3000
BHV3000 (rimegepant) 75 mg or 50 mg ODT
Placebo-VergleichspräparatPlacebo
Matching 75 mg or 50 mg ODT placebo
Passendes Placebo
Matching 75 mg or 50 mg ODT placebo
Hauptergebnismessungen
ErgebnismessungBeschreibung der MessungZeitrahmen
To evaluate the efficacy of rimegepant compared with placebo in the acute treatment of migraine in adolescent population (≥ 12 to <18 years of age) as measured by pain freedom using the number of patients reporting no pain.
Pain freedom will be assessed in adolescent population (≥ 12 to \< 18 years of age) on a 4-point numeric rating scale (0=none, 1=mild, 2=moderate, 3=severe).
2 hours post-dose
Nebenergebnismessungen
ErgebnismessungBeschreibung der MessungZeitrahmen
To compare rimegepant with placebo for pain freedom in children and adolescents combined.
Pain freedom will be assessed in children and adolescents (≥ 6 to \< 18 years of age) using a 4-point numeric rating scale (0=none, 1=mild, 2=moderate, 3=severe). Pain freedom will be assessed in children (\> 6 to \< 12 years of age) using the 5-Face VAS (Face 5 = 'severe pain', Faces 4 and 3 = 'moderate pain', Face 2 = 'mild pain', Face 1 = 'no pain').
2 hours post-dose
To compare rimegepant with placebo on freedom from the most bothersome symptom (MBS) associated with migraine in adolescents.
Freedom from MBS (nausea, phonophobia or photophobia) will be measured using a binary scale (0=absent, 1=present).
2 hours post-dose
To compare rimegepant with placebo on the probabilities of requiring rescue medication within in adolescents.
Use of rescue medication will be assessed using the numbers of participants that take rescue medication.
Within 24 hours and 48 hours of initial treatment
To compare rimegepant with placebo on sustained pain freedom in adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 24 hours post-dose
To compare rimegepant with placebo on sustained pain freedom in adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 48 hours post-dose
To compare rimegepant with placebo on the ability to function normally as reported on the Functional Disability scale in adolescents.
The proportion of participants able to function normally will be assessed using the number that self-report as "normal" on the Functional Disability scale.
2 hours post-dose
To compare rimegepant with placebo for pain freedom in children.
Pain freedom will be assessed using the number of children (≥ 6 to \< 12 years of age) that report no pain measured by a 5-Face VAS (Face 5 = 'severe pain', Faces 4 and 3 = 'moderate pain', Face 2 = 'mild pain', Face 1 = 'no pain').
2 hours post-dose
To compare rimegepant with placebo on freedom from the most bothersome symptom (MBS) associated with migraine in children and combined children and adolescents.
Freedom from the most bothersome symptom (nausea, phonophobia or photophobia) will be assessed using the number of participants that report the absence of MBS measured using a binary scale (0=absent, 1=present).
2 hours post-dose
To compare rimegepant with placebo on the probabilities of requiring rescue medication in children and combined children and adolescents.
The probabilities of requiring rescue medication will be assessed using the numbers of participants that take rescue medication within initial treatment.
Within 24 hours and 48 hours of initial treatment.
To compare rimegepant with placebo on sustained pain freedom in children and combined children and adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 24 hours post-dose
To compare rimegepant with placebo on sustained pain freedom in children and combined children and adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 48 hours post-dose
To compare rimegepant with placebo on freedom from photophobia in adolescents, children and combined children and adolescents.
Freedom from photophobia will be assessed by the number of participants that report the absence of photophobia post dose that reported the presence of photophobia at baseline.
2 hours post-dose
To compare rimegepant with placebo on freedom from phonophobia in adolescents, children and combined children and adolescents.
Freedom from phonophobia will be assessed by the number of participants that report the absence of phonophobia post dose that reported the presence of phonophobia at baseline.
2 hours post-dose
To compare rimegepant with placebo on freedom from nausea in adolescents, children and combined children and adolescents.
Freedom from nausea will be assessed by the number of participants that report the absence of nausea post dose that reported the presence of nausea at baseline.
2 hours post-dose
To compare rimegepant with placebo on pain relief in adolescents, children and combined children and adolescents.
Pain relief will be assessed using the number of participants that report a pain level of moderate or severe at baseline and then report a pain level of none or mild post dose.
2 hours post-dose
To compare rimegepant with placebo in adolescents, children and combined children and adolescents on pain relief.
Time to first report of pain relief will be based on the first time point a participant reports a pain level of none or mild.
Time to patients first report of pain relief of none or mild post dose up to 48 hours.
Teilnahme-Assistent
Eignungskriterien

Zugelassene Altersgruppen
Kind
Mindestalter
6 Years
Zugelassene Geschlechter
Alle

  1. History of migraine (with or without aura) for > 6 months before Screening according to the IHS Classification ICHD-319 specifications for pediatric migraine. History may be verified using both medical records and recall by the participant and/or participant's parent(s)/legal representative(s).

  2. History of 1 to 8 moderate or severe attacks per month during the 2 months prior to enrollment, with attacks lasting > 3 hours without treatment, and attacks occurring at intervals > 24 hours.

  3. Prophylactic migraine medication are permitted if the dose has been stable for at least 12 weeks prior to the Baseline Visit, and the dose is not expected to change during the course of the study.

    1. Participants may remain on one (1) medication with possible migraine prophylactic effects, excluding CGRP antagonists \[biologic or small molecule\], during the treatment phases.
    2. Concomitant use of a CGRP antagonist, such as erenumab or fremanezumab, is prohibited.
    3. Previously discontinued prophylactic migraine medication must have done so at least 90 days prior to the Screening Visit.

  4. Verbally distinguish between migraine and other types of headaches.

  5. Participants must have a weight > 40 kg at the Screening Visit.

  6. Adequate venous access for blood sampling.

  7. Male and female participants ≥ 6 to < 18 years of age (participants must not reach their 18th birthday during the study).

  1. History of cluster headache or hemiplegic migraine headache.
  2. Confounding and clinically significant pain syndrome that may interfere with the participant's ability to participate in this study.
  3. Current psychiatric condition that is uncontrolled and/or untreated for a minimum of 6 months prior to the Screening Visit. Participants with a lifetime history of psychosis and/or mania.
  4. History of suicidal behavior or major psychiatric disorder.
  5. Current diagnosis or history of substance abuse; positive drug test at Screening.
  6. History of moderate or severe head trauma or other neurological disorder (including seizure disorder) or systemic medical disease that is likely to affect central nervous system functioning.
  7. Recent or planned surgery, requiring general anesthesia, <8 weeks prior to the Screening Visit.
  8. Participant has had gastrointestinal surgery that interferes with physiological absorption and motility (i.e., gastric bypass, duodenectomy, or gastric banding).
  9. Current diagnosis of viral hepatitis or a history of liver disease.
  10. Conditions considered clinically relevant in the context of the study such as uncontrolled hypertension (high blood pressure), diabetes, a life-threatening allergy
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Zentrale Studienkontakte
Kontakt: Pfizer Pfizer CT.gov Call Center, 1-800-718-1021, [email protected]
245 Studienstandorte in 9 Ländern

Alabama

Achieve Clinical Research, LLC d/b/a Accel Research Sites-Neurology and Neurodiagnostic of Alabama, Birmingham, Alabama, 35244, United States
Aktiv, nicht rekrutierend

Arizona

Perseverance Research Center, LLC, Scottsdale, Arizona, 85253, United States
Offene Rekrutierung
Physicians Research Group, Tempe, Arizona, 85284, United States
Aktiv, nicht rekrutierend

California

Advanced Research Center, Inc., Anaheim, California, 92805, United States
Offene Rekrutierung
Adult & Child Neurology Medical Associates, Costa Mesa, California, 92627, United States
Offene Rekrutierung
ProScience Research Group, Culver City, California, 90230, United States
Offene Rekrutierung
Memorial Health Services, Fountain Valley, California, 92708, United States
Offene Rekrutierung
Neuro-Pain Medical Center, Fresno, California, 93710, United States
Offene Rekrutierung
Regents of the University of California (UC San Diego), La Jolla, California, 92093, United States
Offene Rekrutierung
Adult & Child Neurology Medical Associates, Long Beach, California, 90806, United States
Offene Rekrutierung
Miller Children's & Women's Hospital Long Beach, Long Beach, California, 90806, United States
Offene Rekrutierung
National Research Institute, Los Angeles, California, 90057, United States
Aktiv, nicht rekrutierend
Velocity Clinical Research - North Hollywood, North Hollywood, California, 91606, United States
Aktiv, nicht rekrutierend
Children's Hospital of Orange County - Inpatient Pharmacy, Orange, California, 92868, United States
Noch nicht rekrutierend
Children's Hospital of Orange County - Neuroscience Center, Orange, California, 92868, United States
Noch nicht rekrutierend
Children's Hospital of Orange County, Orange, California, 92868, United States
Noch nicht rekrutierend
The Neurology Group, Pomona, California, 91767, United States
Offene Rekrutierung
University of California, Davis Midtown Clinic, Sacramento, California, 95816, United States
Aktiv, nicht rekrutierend
UC Davis Medical Center, Investigational Drug Service (IDS) Pharmacy, Sacramento, California, 95817, United States
Aktiv, nicht rekrutierend
University of California, Davis Clinical and Translational Science Center Clinical Research (CCRC), Sacramento, California, 95817, United States
Aktiv, nicht rekrutierend
Velocity Clinical Research, San Bernardino (IP Delivery and Administering Location), San Bernardino, California, 92408, United States
Offene Rekrutierung
Pacific Clinical Research Management Group LLC, Upland, California, 91786, United States
Aktiv, nicht rekrutierend
Sunwise Clinical Research, Walnut Creek, California, 94596, United States
Offene Rekrutierung

Colorado

Children's Hospital Colorado- lnvestigational Drug Services, Aurora, Colorado, 80045, United States
Offene Rekrutierung
Children's Hospital Colorado, Aurora, Colorado, 80045, United States
Offene Rekrutierung
Colorado Springs Neurological Associates, PC, Colorado Springs, Colorado, 80907, United States
Offene Rekrutierung
Colorado Springs Neurological Associates, PC, Colorado Springs, Colorado, 80919, United States
Offene Rekrutierung

Connecticut

CT Clinical Research, Cromwell, Connecticut, 06416, United States
Offene Rekrutierung
Connecticut Children's Medical Center, Hartford, Connecticut, 06106, United States
Aktiv, nicht rekrutierend
Ki Health Partners, LLc, dba New England Institute for Clinical Research, Stamford, Connecticut, 06905, United States
Offene Rekrutierung

Delaware

Nemours Children's Hospital, Delaware, Wilmington, Delaware, 19803, United States
Aktiv, nicht rekrutierend

District of Columbia

Children's National Medical Center, Washington D.C., District of Columbia, 20010, United States
Offene Rekrutierung

Florida

Topaz Clinical Research, Inc., Apopka, Florida, 32703, United States
Aktiv, nicht rekrutierend
Beautiful Minds Clinical Research Center, Cutler Bay, Florida, 33157, United States
Abgebrochen
DeLand Clinical Research Unit, DeLand, Florida, 32720, United States
Abgebrochen
Sarkis Clinical Trials, Gainesville, Florida, 32607, United States
Aktiv, nicht rekrutierend
Multi-Specialty Research Associates, Inc., Lake City, Florida, 32055, United States
Aktiv, nicht rekrutierend
Watson Clinic Center for Research, Inc., Lakeland, Florida, 33805, United States
Abgebrochen
Watson Clinic LLP, Lakeland, Florida, 33805, United States
Abgebrochen
AppleMed Research Group, LLC, Miami, Florida, 33126, United States
Offene Rekrutierung
Medical Research Center of Miami II, Inc, Miami, Florida, 33134, United States
Aktiv, nicht rekrutierend
Nicklaus Children's Hospital, Research Institute, Miami, Florida, 33155, United States
Noch nicht rekrutierend
South Florida Research Phase I-IV, Inc, Miami, Florida, 33166, United States
Offene Rekrutierung
Brainstorm Research, Miami, Florida, 33176, United States
Aktiv, nicht rekrutierend
Advanced Research for Health Improvement, LLC/ Dr. Cordero's Pediatric Office, Naples, Florida, 34102, United States
Aktiv, nicht rekrutierend
Aqualane Clinical Research, Naples, Florida, 34105, United States
Offene Rekrutierung
Coastal Clinical Research Specialists, Orange Park, Florida, 32073, United States
Aktiv, nicht rekrutierend
Clinical Associates of Orlando, LLC, Orlando, Florida, 32819, United States
Offene Rekrutierung
Bioresearch Institute, Pembroke Pines, Florida, 33026, United States
Abgebrochen
Forcare Clinical Research, Tampa, Florida, 33613, United States
Offene Rekrutierung
Premiere Research Institute at Palm Beach Neurology, West Palm Beach, Florida, 33407, United States
Aktiv, nicht rekrutierend

Georgia

Children's Healthcare of Atlanta, Inc., Atlanta, Georgia, 30329, United States
Offene Rekrutierung
Childrens Healthcare of Atlanta, Atlanta, Georgia, 30329, United States
Offene Rekrutierung
Rare Disease Research, LLC, Atlanta, Georgia, 30329, United States
Aktiv, nicht rekrutierend
Pivotal Clinical Research & Associates, LLC, Brunswick, Georgia, 31520, United States
Offene Rekrutierung
CenExel iResearch, LLC, Decatur, Georgia, 30030, United States
Offene Rekrutierung

Illinois

Chicago Headache Center & Research Institute, Chicago, Illinois, 60657, United States
Offene Rekrutierung
AMR-Baber Research Inc, Naperville, Illinois, 60563, United States
Offene Rekrutierung

Indiana

Options Research Group, LLC, Westfield, Indiana, 46074, United States
Offene Rekrutierung

Iowa

Velocity Clinical Research, Sioux City, Sioux City, Iowa, 51106, United States
Offene Rekrutierung
Integrated Clinical Trial Services, West Des Moines, Iowa, 50265, United States
Offene Rekrutierung

Kansas

Clinical Associates Midwest, LLC, Kansas City, Kansas, 66214, United States
Offene Rekrutierung
College Park Family Care Center Physicians Group- Neurology Research Dept., Overland Park, Kansas, 66212, United States
Aktiv, nicht rekrutierend

Kentucky

Kentucky Neuroscience Institute Child Neurology-- "Patients Seen", Lexington, Kentucky, 40504, United States
Aktiv, nicht rekrutierend
UK Center for Clinical and Translational Science (CCTS) -- "Patients Seen", Lexington, Kentucky, 40536, United States
Aktiv, nicht rekrutierend
University of Kentucky Hospital, Lexington, Kentucky, 40536, United States
Aktiv, nicht rekrutierend

Louisiana

Ochsner Clinic Foundation, New Orleans, Louisiana, 70121, United States
Aktiv, nicht rekrutierend
Neurology and Headache Center, Inc., Shreveport, Louisiana, 71105, United States
Aktiv, nicht rekrutierend

Massachusetts

Boston Clinical Trials, Boston, Massachusetts, 02131, United States
Aktiv, nicht rekrutierend
MedVadis Research Corporation, Waltham, Massachusetts, 02451, United States
Aktiv, nicht rekrutierend

Michigan

Michigan Head Pain & Neurological Institute, Ann Arbor, Michigan, 48104, United States
Offene Rekrutierung
Corewell Health, for and on behalf of Spectrum Health Hospital and Corewell Health Medical Group, Grand Rapids, Michigan, 49503, United States
Offene Rekrutierung
Corewell Health, Helen DeVos Children's Hospital, Grand Rapids, Michigan, 49503, United States
Offene Rekrutierung
Wellnow Urgent Care and Research, Kalamazoo, Michigan, 49048, United States
Aktiv, nicht rekrutierend
Beaumont Hospital Royal Oak Campus, Royal Oak, Michigan, 48073, United States
Offene Rekrutierung

Minnesota

Brackenridge Outpatient Research Pharmacy, Rochester, Minnesota, 55905, United States
Offene Rekrutierung
Clinical Research Trials Unit, Rochester, Minnesota, 55905, United States
Offene Rekrutierung
Mayo Clinic, Rochester, Minnesota, 55905, United States
Offene Rekrutierung

Mississippi

Precise Research Centers, Flowood, Mississippi, 39232, United States
Offene Rekrutierung

Missouri

Sharlin Health Neuroscience Research Center, Ozark, Missouri, 65721, United States
Offene Rekrutierung
Clinvest Research, LLC, Springfield, Missouri, 65810, United States
Aktiv, nicht rekrutierend

Montana

Boeson Research, Great Falls, Montana, 59405, United States
Offene Rekrutierung
Boeson Research, Kalispell, Montana, 59901, United States
Aktiv, nicht rekrutierend
Heart & Hands Midwifery, Kalispell, Montana, 59901, United States
Aktiv, nicht rekrutierend
Blue Moose Pediatrics, Missoula, Montana, 59804, United States
Offene Rekrutierung
Boeson Research Laboratory, Missoula, Montana, 59804, United States
Offene Rekrutierung
Boeson Research, Missoula, Montana, 59804, United States
Offene Rekrutierung

Nebraska

Alivation Research, LLC., Lincoln, Nebraska, 68526, United States
Abgebrochen
Children's Hospital & Medical Center, Omaha, Nebraska, 68114, United States
Offene Rekrutierung

New Jersey

HMH Jersey Shore University Medical Center, Neptune City, New Jersey, 07753, United States
Offene Rekrutierung

New York

Dent Neurosciences Research Center, Amherst, New York, 14226, United States
Offene Rekrutierung
True North Neurology, Commack, New York, 11725, United States
Offene Rekrutierung
Northwell Health/ Division of Pediatric Neurology, Lake Success, New York, 11042, United States
Offene Rekrutierung
NYU Langone Hospital-Long Island, Clinical Research Center, Mineola, New York, 11501, United States
Aktiv, nicht rekrutierend
NYU Langone Hospital-Long Island, Pediatric Neurology, Mineola, New York, 11501, United States
Aktiv, nicht rekrutierend
New York Neurology Associates, New York, New York, 10003, United States
Offene Rekrutierung
Weill Cornell Medicine, New York, New York, 10021, United States
Offene Rekrutierung
Mount Sinai Hospital - Pharmacy Department, New York, New York, 10029, United States
Aktiv, nicht rekrutierend
Columbia University Medical Center Research Pharmacy, New York, New York, 10032, United States
Aktiv, nicht rekrutierend
Columbia University Pediatric Neuromuscular Center, New York, New York, 10032, United States
Aktiv, nicht rekrutierend
Irving Center for Clinical and Translational Research, Outpatient Clinical Research Unit, New York, New York, 10032, United States
Aktiv, nicht rekrutierend
The Neurological Institute of New York, New York, New York, 10032, United States
Aktiv, nicht rekrutierend
The Trustees of Columbia University and The New York and Presbyterian Hospital, New York, New York, 10032, United States
Aktiv, nicht rekrutierend
North Suffolk Neurology P.C, Port Jefferson Station, New York, 11776, United States
Aktiv, nicht rekrutierend
Finger Lakes Clinical Research, Rochester, New York, 14618, United States
Abgebrochen
Prime Global Research, LLC, The Bronx, New York, 10456, United States
Abgebrochen

North Carolina

New Hope Clinical Research, Charlotte, North Carolina, 28211, United States
Aktiv, nicht rekrutierend
OnSite Clinical Solutions, LLC, Charlotte, North Carolina, 28277, United States
Offene Rekrutierung
Velocity Clinical Research, Inc., Durham, North Carolina, 27701, United States
Offene Rekrutierung
Headache Wellness Center, PC, Greensboro, North Carolina, 27405, United States
Offene Rekrutierung

Ohio

Akron Children's Hospital, Akron, Ohio, 44308, United States
Offene Rekrutierung
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229, United States
Offene Rekrutierung
Velocity Clinical Research, Cincinnati, Ohio, 45242, United States
Offene Rekrutierung
University Hospitals Cleveland Medical Center, Cleveland, Ohio, 44106, United States
Offene Rekrutierung
Nationwide Children's Hospital, Columbus, Ohio, 43205, United States
Aktiv, nicht rekrutierend
Wellnow Urgent Care and Research, Columbus, Ohio, 43228, United States
Aktiv, nicht rekrutierend
Neuro-Behavioral Clinical Research, Inc., North Canton, Ohio, 44720, United States
Aktiv, nicht rekrutierend

Oklahoma

IPS Research Company, Oklahoma City, Oklahoma, 73106, United States
Aktiv, nicht rekrutierend
Lynn Institute of Tulsa, Tulsa, Oklahoma, 74135, United States
Aktiv, nicht rekrutierend

Oregon

Velocity Clinical Research, Grants Pass, Grants Pass, Oregon, 97527, United States
Aktiv, nicht rekrutierend
Providence Health & Services Investigational Drug Services Westside, Portland, Oregon, 97225, United States
Offene Rekrutierung
Providence Neuroscience Institute - Research Coordinator's Office, Portland, Oregon, 97225, United States
Offene Rekrutierung
Providence Pediatric Neurology, Portland, Oregon, 97225, United States
Offene Rekrutierung
Providence St. Vincent Medical Center, Portland, Oregon, 97225, United States
Offene Rekrutierung

Pennsylvania

Clario, Philadelphia, Pennsylvania, 19103, United States
Offene Rekrutierung
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United States
Aktiv, nicht rekrutierend

Rhode Island

Velocity Clinical Research-Providence, East Greenwich, Rhode Island, 02818, United States
Offene Rekrutierung

South Carolina

Premier Neurology, PC, Greenville, South Carolina, 29605, United States
Aktiv, nicht rekrutierend
Tribe Clinical Research, LLC, Greenville, South Carolina, 29607, United States
Aktiv, nicht rekrutierend
Velocity Clinical Research - Greenville, Greenville, South Carolina, 29615, United States
Aktiv, nicht rekrutierend

Tennessee

Holston Medical Group., Kingsport, Tennessee, 37660, United States
Aktiv, nicht rekrutierend
Holston Medical Group, Kingsport, Tennessee, 37660, United States
Aktiv, nicht rekrutierend
Le Bonheur Children's Hospital - Outpatient Building, Memphis, Tennessee, 38103, United States
Offene Rekrutierung
Le Bonheur Children's Hospital, Memphis, Tennessee, 38103, United States
Offene Rekrutierung
Le Bonheur Childrens Hospital - Childrens Foundation Research Institute, Memphis, Tennessee, 38103, United States
Offene Rekrutierung
Access Clinical Trials, Inc., Nashville, Tennessee, 37203, United States
Aktiv, nicht rekrutierend

Texas

Dell Children's Medical Center, Austin, Texas, 78723, United States
Offene Rekrutierung
Child Neurology Consultants of Austin - South Austin, Austin, Texas, 78749, United States
Offene Rekrutierung
Child Neurology Consultants of Austin - Central Austin, Austin, Texas, 78757, United States
Offene Rekrutierung
BioBehavioral Research of Austin, Austin, Texas, 78759, United States
Aktiv, nicht rekrutierend
Houston Clinical Trials, LLC, Bellaire, Texas, 77401, United States
Offene Rekrutierung
Infinite Research Group, LLC, Dallas, Texas, 75201, United States
Offene Rekrutierung
Children's Medical Center, Dallas, Dallas, Texas, 75235, United States
Offene Rekrutierung
Children's Medical Center, Pediatric Anesthesiology Research (Study supplies only), Dallas, Texas, 75235, United States
Offene Rekrutierung
Cedar Health Research, Dallas, Texas, 75251, United States
Offene Rekrutierung
FutureSearch Trials of Dallas, LLC, Dallas, Texas, 75251, United States
Offene Rekrutierung
The University of Texas Southwestern Medical Center, Dallas, Texas, 75390, United States
Offene Rekrutierung
ANESC Research, El Paso, Texas, 79912, United States
Offene Rekrutierung
North Texas Institute of Neurology and Headache, Frisco, Texas, 75034, United States
Aktiv, nicht rekrutierend
UTHealth Houston, Houston, Texas, 77030, United States
Offene Rekrutierung
Pain and Headache Centers of Texas, Houston, Texas, 77054, United States
Offene Rekrutierung
SCLA Management, Houston, Texas, 77077, United States
Offene Rekrutierung
Houston Clinical Research,LLC., Houston, Texas, 77081, United States
Aktiv, nicht rekrutierend
NeuroCare Plus, Houston, Texas, 77094, United States
Offene Rekrutierung
AIM Trials, LLC, Plano, Texas, 75093, United States
Offene Rekrutierung

Utah

JBR Clinical Research, Salt Lake City, Utah, 84107, United States
Offene Rekrutierung
Wasatch Clinical Research , LLC(Administrative Location), Salt Lake City, Utah, 84107, United States
Offene Rekrutierung

Vermont

The University of Vermont Medical Center, Burlington, Vermont, 05401, United States
Aktiv, nicht rekrutierend

Virginia

Pediatric Research of Charlottesville, LLC (Regulatory Only), Charlottesville, Virginia, 22902, United States
Offene Rekrutierung
Pediatric Research of Charlottesville, LLC, Charlottesville, Virginia, 22902, United States
Offene Rekrutierung
Children's Hospital of the King's Daughters, Norfolk, Virginia, 23507, United States
Offene Rekrutierung
Children's Specialty Group, PLLC, Norfolk, Virginia, 23507, United States
Offene Rekrutierung
Children's Specialty Group, PLLC, Division of Childhood & Adolescent Neurology, Norfolk, Virginia, 23510, United States
Offene Rekrutierung
National Clinical Research, Inc., Richmond, Virginia, 23294, United States
Aktiv, nicht rekrutierend

Washington

Northwest Clinical Research Center, Bellevue, Washington, 98007, United States
Offene Rekrutierung
Eastside Therapeutic Resource, Inc. dba Core Clinical Research, Everett, Washington, 98201, United States
Aktiv, nicht rekrutierend
Seattle Children's Hospital Investigational Drug Services, Seattle, Washington, 98105, United States
Offene Rekrutierung
Seattle Children's Hospital, Seattle, Washington, 98105, United States
Offene Rekrutierung

Wisconsin

Clinical Investigation Specialists, Inc, Kenosha, Wisconsin, 53144, United States
Offene Rekrutierung
University Hospital, Madison, Wisconsin, 53792, United States
Offene Rekrutierung

British Columbia

OCT Research ULC, Kelowna, British Columbia, V1Y 1Z9, Canada
Offene Rekrutierung

Quebec

Diex Recherche Sherbrooke Inc, Sherbrooke, Quebec, J1L 0H8, Canada
Aktiv, nicht rekrutierend

Anhui

First Affiliated Hospital of Bengbu Medical College Neurology, Bengbu, Anhui, 233000, China
Offene Rekrutierung
Anhui Provincial Hospital, Hefei, Anhui, 230000, China
Offene Rekrutierung

Beijing Municipality

Chinese PLA General Hospital, Beijing, Beijing Municipality, 100089, China
Offene Rekrutierung

Chongqing Municipality

" The First Affiliated Hospital of Chongqing Medical University", Chongqing, Chongqing Municipality, 400042, China
Offene Rekrutierung

Gansu

Lanzhou university second hospital, Lanzhou, Gansu, 730030, China
Offene Rekrutierung

Guangdong

Shenzhen Children's Hospital, Shenzhen, Guangdong, 518034, China
Offene Rekrutierung

Hainan

Hainan General Hospital, Haikou, Hainan, 571140, China
Offene Rekrutierung

Hebei

The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, China
Offene Rekrutierung
The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050004, China
Offene Rekrutierung

Henan

People's Hospital of Zhengzhou, Zhengzhou, Henan, 450000, China
Offene Rekrutierung

Hubei

Jingzhou First People's Hospital, Jingzhou, Hubei, 434000, China
Offene Rekrutierung
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China
Offene Rekrutierung
Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
Offene Rekrutierung

Hunan

The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410000, China
Offene Rekrutierung
Hunan Children's Hospital, Changsha, Hunan, 410007, China
Offene Rekrutierung
The Third Xiangya Hospital of Central South University, Changsha, Hunan, 410013, China
Offene Rekrutierung

Jiangsu

The Second People's Hospital of Lianyungang, Lianyungang, Jiangsu, 222002, China
Offene Rekrutierung
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China
Offene Rekrutierung
Wuxi Children's Hospital, Wuxi, Jiangsu, 214023, China
Offene Rekrutierung
Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214115, China
Offene Rekrutierung
Xuzhou Children's Hospital, Xuzhou, Jiangsu, 221002, China
Offene Rekrutierung
Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, China
Offene Rekrutierung

Jilin

The First Hospital of Jilin University, Pediatric Neurology, Changchun, Jilin, 130021, China
Offene Rekrutierung

Ningxia

General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 756000, China
Offene Rekrutierung

Shaanxi

Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China
Offene Rekrutierung
Xi'an Gaoxin Hospital Neurology Department, Xi'an, Shaanxi, 710075, China
Offene Rekrutierung
Yan 'an University Xianyang Hospital, Xianyang, Shaanxi, 716000, China
Offene Rekrutierung

Shandong

Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, 250013, China
Offene Rekrutierung
Liaocheng People's Hospital, Liaocheng, Shandong, 252000, China
Offene Rekrutierung

Sichuan

West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, China
Offene Rekrutierung

Zhejiang

Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310052, China
Offene Rekrutierung
Ningbo Women and Children's Hospital, Ningbo, Zhejiang, 315012, China
Offene Rekrutierung
The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China
Offene Rekrutierung
Lu 'an People's Hospital, Lu'an, China
Offene Rekrutierung
Children's Hospital of Shanghai, Shanghai, China
Offene Rekrutierung
Shengjing Hospital of China Medical University, Shenyang, China
Offene Rekrutierung
The First Affiliated Hospital of Shihezi University School of Medicine, Shihezi, China
Aktiv, nicht rekrutierend
Wuhan Children's Hospital, Wuhan, China
Offene Rekrutierung

Fukuoka

Jinnouchi Neurosurgical Clinic, Kasuga-shi, Fukuoka, 816-0802, Japan
Offene Rekrutierung
Ikeda Neurosurgical Clinic, Kasuga-shi, Fukuoka, 816-0824, Japan
Offene Rekrutierung

Gunma

Hikita Pediatric Clinic, Kiryu-shi, Gunma, 3760035, Japan
Offene Rekrutierung

Hyōgo

Konan Medical Center, Higashinada-ku Kobe-shi, Hyōgo, 658-0064, Japan
Offene Rekrutierung
Yamaguchi Clinic, Nishinomiya-shi, Hyōgo, 663-8204, Japan
Offene Rekrutierung

Ibaraki

Mito Kyodo General Hospital, Mito, Ibaraki, 310-0015, Japan
Offene Rekrutierung

Kagoshima-ken

Tanaka Neurosurgery & Headache Clinic, Kagoshima, Kagoshima-ken, 890-0052, Japan
Offene Rekrutierung

Miyagi

Sendai Headache and Neurology Clinic, Taihaku-ku Sendai-shi, Miyagi, 982-0014, Japan
Offene Rekrutierung

Osaka

Tennoji Dai Brain Clinic, Abeno-ku Osaka-shi, Osaka, 545-0053, Japan
Offene Rekrutierung
Tominaga Clinic, Naniwa-ku, Osaka, 556-0015, Japan
Offene Rekrutierung

Tokyo

Tokyo Headache Clinic, Shibuya-ku, Tokyo, 151-0051, Japan
Offene Rekrutierung
Tokyo Medical University Hospital, Shinjuku-ku, Tokyo, 160-0023, Japan
Noch nicht rekrutierend
Local lndependent Administrative Corporation Hiroshima City Hospital Organization Hiroshima City, Hiroshima, 730-8518, Japan
Offene Rekrutierung

Mexico City

Clinstile S.A. de C.V., Col. Roma Norte, Mexico City, C.P. 06700., Mexico
Offene Rekrutierung

Sinaloa

Neurociencias Estudios Clinicos S.C., Culiacán, Sinaloa, 800200, Mexico
Offene Rekrutierung

State of Mexico

Clinical Reseach Institute, S.C., Tlalnepantla, State of Mexico, C.P. 54055, Mexico
Offene Rekrutierung
Unidad de Investigacion en Salud de Chihuahua S.C., Chihuahua City, 31203, Mexico
Offene Rekrutierung

Lower Silesian Voivodeship

MIGRE Polskie Centrum Leczenia Migreny Anna Gryglas-Dworak, Wroclaw, Lower Silesian Voivodeship, 52-210, Poland
Offene Rekrutierung
NZOZ Wielospecjalistyczna Poradnia Lekarska SYNAPSIS, Lech Szczechowski, Katowice, 40-123, Poland
Aktiv, nicht rekrutierend
Centrum Medyczne Plejady, Krakow, 30-363, Poland
Offene Rekrutierung
Wojewódzki Specjalistyczny Szpital Dzieciecy im. Sw. Ludwika w Krakowie, Apteka Szpitalna, Krakow, 31-503, Poland
Offene Rekrutierung
Clinical Research Center Sp. z.o.o. Medic-R Spolka komandytowa, Poznan, 61-731, Poland
Offene Rekrutierung
Euromedis Sp. z o. o., Szczecin, 70-111, Poland
Aktiv, nicht rekrutierend

Cantabria

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, 39008, Spain
Aktiv, nicht rekrutierend
Hospital Universitario Vall d'Hebron, Barcelona, 08035, Spain
Offene Rekrutierung
Centre d'Atencio Primaria Balenya, Barcelona, 08550, Spain
Aktiv, nicht rekrutierend
Instituto de Investigaciones del Sueno, Madrid, 28036, Spain
Aktiv, nicht rekrutierend
Hospital Universitario Virgen del Rocío, Seville, 41013, Spain
Offene Rekrutierung
Hospital Clinico Universitario de Valladolid, Valladolid, 47005, Spain
Offene Rekrutierung

Skåne LÄN [se-12]

ProbarE i Lund AB, Lund, Skåne LÄN [se-12], 22222, Sweden
Offene Rekrutierung
Avdelningen för kliniska Prövningar, Universitetssjukhuset Örebro, Örebro, 703 62, Sweden
Aktiv, nicht rekrutierend
ProbarE i Stockholm AB, Stockholm, 113 29, Sweden
Offene Rekrutierung
Leicester Royal Infirmary, Leicester, LE1 5WW, United Kingdom
Aktiv, nicht rekrutierend
Re:Cognition Health Limited, London, W1G 9JF, United Kingdom
Offene Rekrutierung
Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, United Kingdom
Offene Rekrutierung