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Die klinische Studie NCT07495774 (INSPIRE-PPH) für Pulmonale Hypertonie ist offene rekrutierung. In der Kartenansicht des Klinische Studien Radar und den KI-Entdeckungstools finden Sie alle Details. Oder stellen Sie hier Ihre Fragen. | ||
Eine Studie entspricht den Filterkriterien
Kartenansicht
Insights Into Pediatric Pulmonary Hypertension: A Real-World Registry of Epidemiology and Outcomes (INSPIRE-PPH) 450 Real-World-Daten Pädiatrisch Jugendliche Beobachtend
Die Details der klinischen Studie sind hauptsächlich auf Englisch verfügbar. Trial Radar KI kann jedoch helfen! Klicken Sie einfach auf 'Studie erklären', um die Informationen zur Studie in der ausgewählten Sprache anzuzeigen und zu besprechen.
Die klinische Studie NCT07495774 (INSPIRE-PPH) ist eine beobachtungsstudie zur Untersuchung von Pulmonale Hypertonie und hat den Status offene rekrutierung. Die Studie startete am 4. Januar 2006 und soll 450 Teilnehmer aufnehmen. Durchgeführt von Guangdong Provincial People's Hospital ist der Abschluss für 31. Dezember 2035 geplant. Die Daten von ClinicalTrials.gov wurden zuletzt am 27. März 2026 aktualisiert.
Kurzbeschreibung
Pediatric pulmonary hypertension (PH) shares similarities with PH in adulthood, but specific differences still require unique approaches. Despite major advances, risk scores for pediatric PH still need to be validated, and targeted drug therapies in pediatric populations remain under-studied. Consequently, there is a great need for comprehensive real-world longitudinal data of pediatric PH.
The INSPIRE-PH registry i...
Mehr anzeigenOffizieller Titel
Insights Into Epidemiology, Management, and Outcomes of Pediatric Pulmonary Hypertension: The INSPIRE-PH Multicenter Real-World Registry
Erkrankungen
Pulmonale HypertonieWeitere Studien-IDs
- INSPIRE-PPH
- INSPIRE-PPH-Registry
NCT-Nummer
Studienbeginn (tatsächlich)
2006-01-04
Zuletzt aktualisiert
2026-03-27
Studienende (vorauss.)
2035-12-31
Geplante Rekrutierung
450
Studientyp
Beobachtungsstudie
Status
Offene Rekrutierung
Stichwörter
pediatric
pulmonary hypertension
real-world
epidemiology
outcome
pulmonary hypertension
real-world
epidemiology
outcome
Hauptergebnismessungen
Nebenergebnismessungen
| Ergebnismessung | Beschreibung der Messung | Zeitrahmen |
|---|---|---|
death | From enrollment to the event, assessed through study completion (target follow-up duration of 10 years; extended follow-up available for earlier enrollees) | |
transplantation | From enrollment to the event, assessed through study completion (target follow-up duration of 10 years; extended follow-up available for earlier enrollees) |
| Ergebnismessung | Beschreibung der Messung | Zeitrahmen |
|---|---|---|
PH-related hospitalization | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
atrial septostomy | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
Potts shunt | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
clinical worsening | Clinical worsening is defined as the first occurrence of death, transplantation, hospitalization for PH, atrial septostomy or Potts shunt, with need for escalation of PH-targeted therapy, or worsening functional status. | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) |
decline in WHO functional class | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) |
Teilnahme-Assistent
Eignungskriterien
Zugelassene Altersgruppen
Kind, Erwachsene
Zugelassene Geschlechter
Alle
- Children and adolescents aged <18 years at diagnosis
- Diagnosed pulmonary hypertension (PH) according to the prevailing diagnostic criteria at the time of enrollment
- Enrollment in the registry at participating centers
- Provision of informed consent by patients and/or legal guardians
- Availability for longitudinal follow-up
- Inability to confirm PH diagnosis due to insufficient clinical or hemodynamic data
- Refusal or inability to provide informed consent
Guangdong Provincial People's HospitalVerantwortliche Partei
Zhi-Cheng Jing, MD, Hauptprüfer, Prof., Guangdong Provincial People's Hospital
Zentrale Studienkontakte
Kontakt: Jie-Xin Zhang, Dr., +86-18629534652, [email protected]
1 Studienstandorte in 1 Ländern
Guangdong
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, 510080, China
Offene Rekrutierung