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Clinical Trial NCT07128875 (OA) for Knee Osteoarthritis is not yet recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
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Therapeutic Exercises for Pain and Disability in Knee Osteoarthritis (OA) 56 Exercise-Based

Not yet recruiting
Clinical Trial NCT07128875 (OA) is an interventional study for Knee Osteoarthritis and is currently not yet recruiting. Enrollment is planned to begin on 17 August 2025 and continue until the study accrues 56 participants. Led by Riphah International University, this study is expected to complete by 17 July 2026. The latest data from ClinicalTrials.gov was last updated on 19 August 2025.
Brief Summary
This study aims to evaluate the effectiveness of structured therapeutic exercises in reducing pain and disability among older adults diagnosed with knee osteoarthritis. The intervention will involve a supervised physical therapy program targeting muscle strength, joint mobility, and functional capacity. Participants will undergo 6 weeks of therapy, and improvements in pain and physical function will be measured using...Show More
Detailed Description
Knee osteoarthritis (OA) is a leading cause of chronic pain and mobility limitations in the elderly population. Therapeutic exercises play a significant role in managing OA symptoms by strengthening the quadriceps, improving joint flexibility, and reducing stiffness. This study will enroll 60 participants aged 50-75 years diagnosed with knee OA. They will undergo a combination of strengthening, range of motion (ROM),...Show More
Official Title

Effectiveness of Therapeutic Exercises in Reducing Pain and Disability in Knee Osteoarthritis Patients in Older Adults

Conditions
Knee Osteoarthritis
Other Study IDs
  • OA
  • RIPHAH-REC Naimat ullah 01018
NCT ID Number
NCT07128875
Start Date (Actual)
2025-08-17
Last Update Posted
2025-08-19
Completion Date (Estimated)
2026-07-17
Enrollment (Estimated)
56
Study Type
Interventional
PHASE
N/A
Status
Not yet recruiting
Keywords
Osteoarthritis, Knee Pain, Therapeutic Exercise
Primary Purpose
Health Services Research
Design Allocation
Randomized
Interventional Model
Parallel
Masking
Triple
Arms / Interventions
Participant Group/ArmIntervention/Treatment
ExperimentalExercise + TENS + Hot Pack
Participants in this group will receive a structured therapeutic exercise program designed to improve physical function and reduce pain in patients with knee osteoarthritis. The session includes: Warm-Up (10 min): Light walking or stationary cycling Range of Motion (ROM) Exercises: Heel slides, seated knee flexion/extension Strengthening Exercises: Quadriceps sets Straight leg raises Mini squats (within pain-f...Show More
Exercise + TENS + Hot Pack
Therapeutic Exercises with Hot Pack and TENS This intervention focuses on improving physical function and reducing pain through structured therapeutic exercises for knee OA patients. The program includes Warm-Up (10 min): Light walking or stationary cycling. 2. Range of Motion (ROM) Exercises: Heel slides, seated knee flexion/extension. 3. Strengthening Exercises: Quadriceps sets Straight leg raises Mini squats (pai...Show More
Active ComparatorExercise Only (Control)
Participants in the control group will follow the same structured therapeutic exercise program as the experimental group. However, TENS will be replaced with a sham procedure that mimics device placement without electrical stimulation. Warm-Up (10 min): Light walking or stationary cycling Range of Motion (ROM) Exercises: Heel slides, seated knee flexion/extension Strengthening Exercises: Quadriceps sets Straight...Show More
Exercise
Warm-Up (10 min): Light walking or stationary cycling. 2. Range of Motion (ROM) Exercises: Heel slides, seated knee flexion/extension. 3. Strengthening Exercises: Quadriceps sets Straight leg raises Mini squats (pain-free range) Seated knee extensions with resistance band 4. Stretching Exercises: Hamstring stretch Calf stretch Quadriceps stretch 5.
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Pain Intensity
Pain intensity will be assessed using the Visual Analog Scale (VAS), which ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores represent worse outcomes.
6 Months
Secondary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Change in Physical Disability
Physical disability will be measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The WOMAC consists of 24 items scored from 0 (none) to 4 (extreme), yielding a total score range from 0 to 96, where higher scores indicate worse disability
6months
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult
Minimum Age
35 Years
Eligible Sexes
All

Minimum Age: 50 Years Maximum Age: 75 Years Sex: All Accepts Healthy Volunteers: No

Inclusion Criteria:

  • Diagnosed with knee OA
  • Aged 50-75 years
  • Experiencing pain or functional limitation
  • Able to attend supervised sessions
  • Provided informed consent

  • History of total knee replacement
  • Severe cardiovascular or neurological conditions
  • Acute injury or fracture in lower limb
  • Uncontrolled hypertension or diabetes
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Study Central Contact
Contact: Dr.Nadeem Ahmad, MS, 03451915105, [email protected]
Contact: Dr.Nadeem Ahmad, MS, 03028367237, [email protected]
1 Study Locations in 1 Countries

Kpk

Riphah international University Malakand Campus, Malakand, Kpk, 23060, Pakistan