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Foundation University IslamabadImpact of Tissue Flossing and Therapeutic Exercises in Patient With Knee Osteoarthritis 58 Randomized Exercise-Based
Clinical Trial NCT07181421 is an interventional study for Knee Osteoarthristis and is currently not yet recruiting. Enrollment is planned to begin on 30 September 2025 and continue until the study accrues 58 participants. Led by Foundation University Islamabad, this study is expected to complete by 1 August 2026. The latest data from ClinicalTrials.gov was last updated on 18 September 2025.
Brief Summary
Knee osteoarthritis (OA) is a common degenerative joint disease that primarily affects individuals aged 40 years and older, and results in painful symptoms along with limited range of motion (ROM) and muscle weakness(1). Therapeutic exercise covers a range of targeted physical activities that directly aim to improve muscle strength, neuromotor control, joint range of motion and aerobic fitness. One of the main aims o...Show More
Detailed Description
Knee Osteoarthritis (OA) is a chronic degenerative joint disorder characterized by the breakdown of articular cartilage, synovial inflammation, and structural changes in subchondral bone, leading to pain, stiffness, and functional limitations (1). Knee OA, the most prevalent form of OA, significantly affects mobility and quality of life, especially in individuals with sedentary lifestyles or obesity. According to the...Show More
Official Title
Impact of Tissue Flossing and Therapeutic Exercises in Patient With Knee Osteoarthritis
Conditions
Knee OsteoarthristisOther Study IDs
- FUI/CTR/2025/05
NCT ID Number
Start Date (Actual)
2025-09-30
Last Update Posted
2025-09-18
Completion Date (Estimated)
2026-08-01
Enrollment (Estimated)
58
Study Type
Interventional
PHASE
N/A
Status
Not yet recruiting
Primary Purpose
Treatment
Design Allocation
Randomized
Interventional Model
Parallel
Masking
None (Open Label)
Arms / Interventions
| Participant Group/Arm | Intervention/Treatment |
|---|---|
ExperimentalTissue Flossing and Therapeutic Exercises Detailed of tissue flossing and therapeutic exercises.: The floss band will be kept on for 2 minutes, and during this time, the patient will perform the exercises with progression. After each 2-minute flossing session, the patient will rest for 2 minutes. | Tissue flossing with Therapeutic exercises Isometric Knee Extension - Standing Hamstring Curl - Wall Squats - Leg Press Against Wall. The Red TheraBand from Thera Tool (2m \* 5cm \* 1.3mm) will be used. The band will be wrapped starting from the tibial tuberosity and extending to 5 cm above the femoral epicondyle. Care will be taken to ensure that the patella remains uncovered.
* The band will be wrapped with 50% tension and 50% overlap.
* Flossing Duration:...Show More |
Active ComparatorTherapeutic Exercises only Isometric Knee Extension - Standing Hamstring Curl - Wall Squats - Leg Press Against Wall | Therapeutic Exercises Isometric Knee Extension - Standing Hamstring Curl - Wall Squats - Leg Press Against Wall. |
Primary Outcome Measures
| Outcome Measure | Measure Description | Time Frame |
|---|---|---|
Knee Pain | Numeric pain rating scale will be used to measure knee pain | 4 weeks |
Knee Range of Motion | Goniometer willl be used to measure knee range of motion | 4 weeks |
Knee Muscle Strength | Manual Muscle Testing will be used for knee muscle strength | 4 weeks |
Participation Assistant
Eligibility Criteria
Eligible Ages
Adult, Older Adult
Minimum Age
40 Years
Eligible Sexes
All
- Adults aged 40-70 years with diagnosed knee OA (Grades 1 and 2). Unilateral knee OA or if bilateral OA is present, only the more symptomatic knee (Grade 1 or 2) Willingness to comply with the intervention protocol. Both Genders
- Higher grade 3 and 4 knee OA. Recent knee surgeries Soft tissue injury of lower limb less than six months prior to the study Neurological or cardiovascular conditions contraindicating exercise Ongoing participation in another knee Rehabilitation program Latex allergy or Skin diseases varicose veins and Thrombosis Diabetic Neuropathy Fractures and open wounds.
Foundation University Islamabad90 active studies to exploreStudy Central Contact
Contact: Noor ul Aqsa, DPT, +923312413859, [email protected]
1 Study Locations in 1 Countries
Punjab Province
Foundation University Islamabad, Islamabad, Punjab Province, 46000, Pakistan
Muhammad Furqan Hassan, MS-MSKPT, Contact, +923334056768, [email protected]