beta
Trial Radar AI
Clinical Trial NCT07364227 for Adhesive Capsulitis of the Shoulder, Intra Articular Injection is not yet recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
One study matched filter criteria
Card View
Back to Search

Anterior vs Posterior vs Combined Intra-Articular Injections for Adhesive Capsulitis 30 Randomized

Not yet recruiting
Clinical Trial NCT07364227 is an interventional study for Adhesive Capsulitis of the Shoulder, Intra Articular Injection and is currently not yet recruiting. Enrollment is planned to begin on 1 January 2026 and continue until the study accrues 30 participants. Led by Aslinur Keles Ercisli, MD, PhD, this study is expected to complete by 1 July 2026. The latest data from ClinicalTrials.gov was last updated on 23 January 2026.
Brief Summary
This randomized controlled clinical trial aims to compare the efficacy of three different intra-articular injection approaches (anterior, posterior, and combined anterior-posterior) in patients with adhesive capsulitis of the shoulder. Thirty participants will be randomly assigned to one of three groups and treated with a standardized injection solution consisting of corticosteroid, lidocaine, and saline. Clinical ou...Show More
Detailed Description
Adhesive capsulitis (frozen shoulder) is a disabling condition characterized by progressive pain and stiffness of the glenohumeral joint. Intra-articular corticosteroid injections are frequently used to reduce pain and improve mobility; however, the optimal injection approach remains controversial.

This single-center randomized controlled trial will investigate three different approaches: posterior, anterior, and co...

Show More
Official Title

Comparison of Anterior, Posterior, and Combined Intra-Articular Injection Techniques in Patients With Adhesive Capsulitis

Conditions
Adhesive Capsulitis of the ShoulderIntra Articular Injection
Other Study IDs
  • ADC2025
NCT ID Number
NCT07364227
Start Date (Actual)
2026-01
Last Update Posted
2026-01-23
Completion Date (Estimated)
2026-07
Enrollment (Estimated)
30
Study Type
Interventional
PHASE
N/A
Status
Not yet recruiting
Keywords
Adhesive Capsulitis of the Shoulder
Intra-articular Injection
Frozen Shoulder
Ultrasound
Shoulder Pain
Primary Purpose
Treatment
Design Allocation
Randomized
Interventional Model
Parallel
Masking
None (Open Label)
Arms / Interventions
Participant Group/ArmIntervention/Treatment
ExperimentalArm A: Posterior Injection
Single intra-articular injection with corticosteroid + lidocaine + saline via the posterior glenohumeral approach.
Intervention Name: Posterior Intra-articular Injection
A single intra-articular injection consisting of 1 cc corticosteroid, 4 cc 2% lidocaine, and 5 cc saline (total 10 cc) administered via the posterior glenohumeral approach.
ExperimentalArm B - Anterior Injection
Same injection solution administered via the anterior (rotator interval) approach.
Anterior Intra-articular Injection
A single intra-articular injection consisting of 1 cc corticosteroid, 4 cc 2% lidocaine, and 5 cc saline (total 10 cc) administered via the anterior (rotator interval) approach.
ExperimentalArm C - Combined Anterior + Posterior Injection
Same injection solution administered using both anterior and posterior approaches.
Combined Anterior + Posterior Intra-articular Injection
A single intra-articular injection consisting of 1 cc corticosteroid, 4 cc 2% lidocaine, and 5 cc saline (total 10 cc) administered using both anterior and posterior approaches during the same procedure.
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Change in Shoulder Range of Motion (ROM)
Change in active and passive shoulder joint range of motion (flexion, extension, abduction, external rotation, internal rotation) measured with a goniometer.
Baseline, immediately post-injection, week 3, week 6, week 12
Secondary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Change in Pain Intensity (NRS)
Number Rating Scale (0-10) for pain at rest, during activity, and at night.
Baseline, immediately post-injection, week 3, week 6, week 12
Subjective Shoulder Value (SSV)
Patient's self-reported percentage of normal shoulder function (0-100%).
Baseline, immediately post-injection, week 3, week 6, week 12
Shoulder Pain and Disability Index (SPADI)
Questionnaire assessing pain and disability (0-100 score, higher scores = worse function).
Baseline, week 3, week 6, week 12
Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH)
Questionnaire measuring upper limb disability and symptoms (0-100 score, higher = worse).
Baseline, week 3, week 6, week 12
American Shoulder and Elbow Surgeons (ASES) Score
Composite score including pain and function (0-100, higher = better).
Baseline, week 3, week 6, week 12
Constant-Murley Shoulder Score
Clinical score combining pain, activities of daily living, strength, and ROM (0-100).
Baseline, week 3, week 6, week 12
Scratch Test Score
Functional test measuring the patient's ability to reach behind the back.
Baseline, immediately post-injection, week 3, week 6, week 12
Axillary Capsule Thickness (Ultrasound)
Ultrasound measurement of axillary recess capsule thickness on the affected shoulder.
Baseline, immediately post-injection (only).
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
Aslinur Keles Ercisli, MD, PhD logoAslinur Keles Ercisli, MD, PhD
Study Responsible Party
Aslinur Keles Ercisli, MD, PhD, Sponsor-Investigator, Principal investigator, Fatih Sultan Mehmet Training and Research Hospital
Study Central Contact
Contact: Aslinur K Keles, MD., PhD, +905395010707, [email protected]
Contact: esra K giray, Assoc Prof, +90 555 813 43 94, [email protected]
No location data.