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Clinical Trial NCT07488702 (GTTIR) for Spinal Cord Neoplasms, Spinal Neoplasms is active, not recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
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Intradurale Spinal Tumors: Management and Treatment (GTTIR) 50 Observational

Active, not recruiting
Clinical Trial NCT07488702 (GTTIR) is an observational study for Spinal Cord Neoplasms, Spinal Neoplasms that is active, not recruiting. It started on 1 January 2022 with plans to enroll 50 participants. Led by Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria, it is expected to complete by 31 December 2026. The latest data from ClinicalTrials.gov was last updated on 27 March 2026.
Brief Summary
Intradurale spinal tumors are rare neoplastic lesions that involve the spinal cord and surrounding structures and may cause neurological symptoms such as pain, motor deficits, sensory disturbances, and sphincter dysfunction. Surgical resection is often the primary treatment when feasible and may improve neurological outcomes and relieve spinal cord compression.

This retrospective observational study aims to analyze ...

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Detailed Description
Intradural spinal tumors are uncommon neoplastic lesions involving the spinal cord and its surrounding structures. These tumors may be classified as intradural extramedullary or intramedullary depending on their origin and anatomical location. Although relatively rare, they represent an important clinical condition due to their potential to cause progressive neurological impairment, including pain, motor weakness, se...Show More
Official Title

Intradurale Spinal Tumors: Management and Treatment - A Retrospective Observational Study

Conditions
Spinal Cord NeoplasmsSpinal Neoplasms
Other Study IDs
  • GTTIR
  • ASO.Nch.25.02
  • Novara Ethical Committee (Other Identifier) (441.170)
NCT ID Number
NCT07488702
Start Date (Actual)
2022-01-01
Last Update Posted
2026-03-27
Completion Date (Estimated)
2026-12-31
Enrollment (Estimated)
50
Study Type
Observational
Status
Active, not recruiting
Keywords
Intradural spinal tumors
Spinal cord neoplasms
Spinal tumor surgery
Neurosurgery
McCormick scale
Neurological outcome
Spinal cord compression
Retrospective study
Arms / Interventions
Participant Group/ArmIntervention/Treatment
Patients With Intradural Spinal Tumors
Patients who underwent surgical treatment for intradural spinal tumors at the Neurosurgery Unit of Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo di Alessandria between 2022 and 2024. Clinical, radiological, and histopathological data were collected retrospectively from medical records to evaluate patient characteristics, neurological outcomes, postoperative complications, and tumor recurrence...Show More
Surgical Resection of Intradural Spinal Tumors
This study consists of retrospective data collection and analysis of patients who underwent neurosurgical resection of intradural spinal tumors. No intervention is assigned as part of the study protocol.
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Neurological Functional Outcome Assessed
Assessment of neurological functional status in patients undergoing surgical resection of intradural spinal tumors using the McCormick functional grading scale (Grade I: neurologically normal or mild deficit; Grade II: mild functional deficit, independent; Grade III: moderate deficit, limited independence; Grade IV: severe deficit, dependent; Grade V: paraplegia or quadriplegia). Preoperative and postoperative scores will be compared to evaluate changes in neurological function.
From preoperative assessment to last available follow-up (up to 24 months post-surgery)
Secondary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Postoperative Complications
Evaluation of postoperative complications, including hemorrhage, infections, dural fistula, and new neurological deficits, occurring after surgical treatment of intradural spinal tumors.
From surgery to 30 days postoperatively
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
  • Patients hospitalized at Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo di Alessandria (Neurosurgery Unit).
  • Patients who underwent surgical resection of an intradural spinal tumor.
  • Diagnosis consistent with intradural spinal tumors according to ICD-9 codes.
  • Availability of clinical, radiological, and surgical data in medical records.
  • Signed informed consent.

  • Incomplete medical records or missing clinical data required for the study.
  • Tumors with uncertain extradural extension identified during surgery.
  • Tumors arising from peripheral nerves.
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria logoAzienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
No contact data.
1 Study Locations in 1 Countries

Italia

Neurosurgery Unit, Alessandria, Italia, 15121, Italy