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Clinical Trial NCT07491250 for Inguinal Hernia Repair, Mesh Infection is not yet recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
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Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis 100

Not yet recruiting
Clinical Trial NCT07491250 is an observational study for Inguinal Hernia Repair, Mesh Infection and is currently not yet recruiting. Enrollment is planned to begin on 18 March 2026 and continue until the study accrues 100 participants. Led by Fudan University, this study is expected to complete by 31 July 2026. The latest data from ClinicalTrials.gov was last updated on 24 March 2026.
Brief Summary
Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required. This study compared clinical outcomes of complete versus partial mesh removal in affected patients.

Materials and Methods: We retrospectively analyzed patients who underwent surgery for mesh infection after IHR in our hospital between January 2016 and Decem...

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Detailed Description
We conducted a single-center, retrospective case series analysis. We included patients who developed mesh infection after tension-free IHR and underwent surgical treatment at our center between January 2016 and December 2025. Patients with mesh infection after incisional, parastomal, or umbilical hernia repair were excluded. We also excluded patients who improved with conservative treatment and did not undergo surger...Show More
Official Title

A Retrospective Study: Complete vs Partial Mesh Removal for Mesh Infection After Hernioplasty - Clinical Outcomes and Pathogen Analysis

Conditions
Inguinal Hernia RepairMesh Infection
Other Study IDs
  • HuadongHosptialHernia02
NCT ID Number
NCT07491250
Start Date (Actual)
2026-03-18
Last Update Posted
2026-03-24
Completion Date (Estimated)
2026-07-31
Enrollment (Estimated)
100
Study Type
Observational
Status
Not yet recruiting
Keywords
Inguinal hernia repair
mesh infection
complete mesh removal
partial mesh removal
Arms / Interventions
Participant Group/ArmIntervention/Treatment
The complete mesh removal group
Complete mesh removal
Total explantation of the entire prosthetic mesh, including all visible portions and fixation sutures, regardless of the extent of infection.
The partial mesh removal group
Partial mesh removal
Excision of only the infected or non-incorporated portion of the mesh, with preservation of the well-incorporated, uninfected segment left in situ.
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Hernia Recurrence Rate
Presence of clinically or radiologically confirmed recurrent inguinal hernia at the site of previous hernioplasty following mesh removal surgery.
From date of surgery to December 2025
Infection Recurrence Rate
Recurrence of surgical site infection at the same location after initial surgical treatment for mesh infection, confirmed by clinical signs (e.g., erythema, purulent drainage, sinus tract formation) and/or positive microbiological culture.
From date of surgery to December 2025
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
Accepts Healthy Volunteers
Yes
  1. Patients who underwent tension-free inguinal hernioplasty with mesh placement.
  2. Patients diagnosed with mesh infection requiring surgical re-intervention.
  3. Patients who underwent complete or partial mesh removal surgery.
  4. Availability of complete medical records and follow-up data.

  1. Patients with mesh infection managed conservatively (without surgical removal).
  2. Patients with missing critical data (e.g., intraoperative findings, pathogen results, or follow-up).
  3. Patients with concomitant procedures that could confound outcomes (e.g., simultaneous other hernia repair).
  4. Patients lost to follow-up immediately after discharge (no postoperative assessment).
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Study Responsible Party
Zhijun Bao, Principal Investigator, Director, Fudan University
Study Central Contact
Contact: Xiaoyu Peng, MD, +8619121706827, [email protected]
No location data.