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Clinical Trial NCT07492147 for Kidney Stones is recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
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Effect of Negative Pressure Suction on Fluid Absorption and Infection in Flexible Ureteroscopy 400 Observational

Recruiting
Clinical Trial NCT07492147 is an observational study for Kidney Stones that is recruiting. It started on 9 March 2026 with plans to enroll 400 participants. Led by Lanzhou University Second Hospital, it is expected to complete by 7 July 2027. The latest data from ClinicalTrials.gov was last updated on 25 March 2026.
Brief Summary

The goal of this observational study is to learn about the effects of using negative pressure suction during retrograde intrarenal surgery (RIRS) in patients aged 18 and older with kidney stones. The main questions it aims to answer are:

  1. Does using negative pressure suction during surgery affect the amount of irrigation fluid absorbed by the patient's body?
  2. Does using negative pressure suction reduce the risk ...
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Official Title

Impact of Negative Pressure Suction on Irrigation Fluid Absorption and Postoperative Infection Risk During Flexible Ureteroscopic Lithotripsy: A Prospective Cohort Study

Conditions
Kidney Stones
Other Study IDs
  • 2025A-1369
NCT ID Number
NCT07492147
Start Date (Actual)
2026-03-09
Last Update Posted
2026-03-25
Completion Date (Estimated)
2027-07-07
Enrollment (Estimated)
400
Study Type
Observational
Status
Recruiting
Arms / Interventions
Participant Group/ArmIntervention/Treatment
Negative Pressure Suction Sheath Group
Patients who undergo retrograde intrarenal surgery (RIRS) using a ureteral access sheath with a negative pressure suction system.
N/A
Standard Ureteral Access Sheath Group
Patients who undergo retrograde intrarenal surgery (RIRS) using a standard ureteral access sheath without a negative pressure suction system.
N/A
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Volume of irrigation fluid absorbed
Intraoperative (During the surgery)
Secondary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Incidence of postoperative fever and infectious complication
Up to 7 days postoperatively
ostoperative length of hospital stay
From surgery to hospital discharge (an average of 3-7 days)
Stone-free rate (SFR)
1 month postoperatively
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
  • Patients aged 18 years and older with kidney stones who meet the surgical indications for RIRS;
  • Patients who have provided informed consent.

  • Concurrent combination with other surgical procedures, such as percutaneous nephrolithotomy (PCNL);
  • Patients with malignancies, urinary tuberculosis, immune system diseases, or hyperthyroidism;
  • Congenital renal anomalies, such as polycystic kidney disease or horseshoe kidney;
  • Presence of untreated urinary tract infections;
  • Inability to tolerate surgery due to severe cardiopulmonary dysfunction, hepatic or renal insufficiency, or coagulation abnormalities.
Lanzhou University Second Hospital logoLanzhou University Second Hospital
Study Responsible Party
Zhiping Wang, Principal Investigator, Professor; Chief Physician, Lanzhou University Second Hospital
Study Central Contact
Contact: Zhiping Wang, 13893131697, [email protected]
1 Study Locations in 1 Countries

Gansu

Lanzhou University Second Hospital, Lanzhou, Gansu, 730030, China
Guilin Wang, Contact, 18386255271, [email protected]
Recruiting