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Clinical Trial NCT07496125 for Acute Brain Injuries, Mechanical Ventilation is recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
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Retrospective Study on Ventilator Weaning Outcomes in Patients With Acute Brain Injury 1,500 Observational

Recruiting
Clinical Trial NCT07496125 is an observational study for Acute Brain Injuries, Mechanical Ventilation that is recruiting. It started on 1 January 2018 with plans to enroll 1,500 participants. Led by Southeast University, China, it is expected to complete by 1 March 2026. The latest data from ClinicalTrials.gov was last updated on 27 March 2026.
Brief Summary
Invasive mechanical ventilation (IMV) is a life-saving supportive therapy for patients with acute brain injury, which accounted for nearly one-fifth of all mechanically ventilated patients in the intensive care unit (ICU). However, prolonged exposure to IMV is consistently associated with an increased risk of ventilator-related complications and adverse outcomes. Accordingly, alongside the initiation of IMV, timely a...Show More
Official Title

Weaning Outcomes in Patients With Acute Brain Injury Based on CDIC

Conditions
Acute Brain InjuriesMechanical Ventilation
Other Study IDs
  • Retro WEAN ABI
NCT ID Number
NCT07496125
Start Date (Actual)
2018-01-01
Last Update Posted
2026-03-27
Completion Date (Estimated)
2026-03
Enrollment (Estimated)
1,500
Study Type
Observational
Status
Recruiting
Arms / Interventions
Participant Group/ArmIntervention/Treatment
Classified by weaning outcomes
N/A
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
weaning outcome
The primary endpoint was the weaning outcome according to the modified WIND classification
day 90
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
  • Patients with ABI
  • ≥ 18 years old
  • underwent IMV for at least 24 hours

  • already tracheostomized
  • concurrent of cervical spinal cord injury
  • pregnant or lactation
  • withdraw of life-sustaining treatment within the first 24 hours of ICU admission
Southeast University, China logoSoutheast University, China
Study Responsible Party
Ling Liu, Principal Investigator, PhD & MD, Southeast University, China
Study Central Contact
Contact: Ling Liu, PHD, 86+83262553, [email protected]
Contact: Rui Zhang, MD, [email protected]
1 Study Locations in 1 Countries

Jiangsu

Department of Critical Care Medicine, Zhongda Hospital, Nanjing, Jiangsu, 210009, China
Ling Liu, PhD, Contact, 86+83262553, [email protected]
Recruiting