Trial Radar AI | ||
|---|---|---|
Clinical Trial NCT07218380 (FORAGER-2) for Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis is not yet recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here. | ||
One trial matched filter criteria
Card View
Back to Search
Eli Lilly and CompanyA Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract (FORAGER-2)
Clinical Trial NCT07218380 (FORAGER-2) is designed to study Treatment for Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis. This Phase 3 interventional trial is not yet recruiting. Enrollment is planned to begin on 1 November 2025 until the trial accrues 450 participants. Led by Eli Lilly and Company, this trial is expected to complete by 1 May 2033. The latest data from ClinicalTrials.gov was last updated on 24 November 2025.
Brief Summary
The purpose of this study is to test a new medicine, vepugratinib, in comparison with placebo, to see if it is safe and can help people with a bladder cancer that is advanced or has spread.
Vepugratinib or placebo will be administered in combination with enfortumab vedotin and pembrolizumab.
Study participation could last up to approximately 6 years.
Official Title
FORAGER-2: A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Vepugratinib Combined With Enfortumab Vedotin and Pembrolizumab in Adults With Untreated Locally Advanced or Metastatic Urothelial Carcinoma With an FGFR3 Genetic Alteration
Conditions
Carcinoma, Transitional CellUrinary Bladder NeoplasmsNeoplasm MetastasisOther Study IDs
- FORAGER-2
- 27333
- J4G-MC-JZVD (Other Identifier) (Eli Lilly and Company)
- 2025-522855-25-00 (EU Trial (CTIS) Number)
NCT ID Number
Start Date (Actual)
2025-11
Last Update Posted
2025-11-24
Completion Date (Estimated)
2033-05
Enrollment (Estimated)
450
Study Type
Interventional
PHASE
Phase 3
Status
Not yet recruiting
Keywords
FGFR3
Advanced Urothelial Carcinoma
Metastatic Urothelial Carcinoma
Advanced Urothelial Carcinoma
Metastatic Urothelial Carcinoma
Primary Purpose
Treatment
Design Allocation
Randomized
Interventional Model
Parallel
Masking
Double
Arms / Interventions
| Participant Group/Arm | Intervention/Treatment |
|---|---|
ExperimentalVepugratinib + EV + Pembrolizumab (Safety Lead In) Vepugratinib administered orally with EV + pembrolizumab administered IV | Vepugratinib Administered orally EV Administered by IV infusion Pembrolizumab Administered by IV infusion |
ExperimentalVepugratinib + Enfortumab Vedotin (EV) + Pembrolizumab Vepugratinib administered orally, and EV + pembrolizumab administered by intravenous (IV) infusion. | Vepugratinib Administered orally EV Administered by IV infusion Pembrolizumab Administered by IV infusion |
Placebo ComparatorPlacebo + EV + Pembrolizumab Placebo administered orally, and EV + pembrolizumab administered by IV infusion. | Placebo Administered orally EV Administered by IV infusion Pembrolizumab Administered by IV infusion |
Primary Outcome Measures
Secondary Outcome Measures
| Outcome Measure | Measure Description | Time Frame |
|---|---|---|
Number of participants with treatment-related adverse events related to vepugratinib in combination with EV and pembrolizumab | From baseline up to 90 months | |
Safety Lead-in: Overall Response Rate (ORR) | ORR by Investigator Assessment. | From baseline up to 90 months |
Progression-free Survival (PFS) | PFS by blinded independent committee review (BICR). | Baseline to Study Completion (estimated as 6 years) |
| Outcome Measure | Measure Description | Time Frame |
|---|---|---|
Safety Lead-in: Disease Control Rate (DCR) | DCR by investigator assessment. | From baseline up to the end of Cycle 2 (each Cycle is 21 days) |
Safety Lead-in: Time to Response (TTR) | TTR by investigator assessment. | From baseline up to 90 months |
Overall Survival (OS) | Baseline to Study Completion (estimated as 6 years) | |
Objective Response Rate (ORR) by BICR | Baseline to Study Completion (estimated as 6 years) | |
Duration of Response (DoR) | DOR by BICR. | Baseline to Study Completion (estimated as 6 years) |
Progression-free Survival (PFS) | PFS by investigator assessment. | Baseline to Study Completion (estimated as 6 years) |
Objective Response Rate (ORR) | Percentage of Participants who Achieve a Best Overall Response (BOR) of Complete Response (CR) or Partial Response (PR)ORR by investigator assessment | Baseline to Study Completion (estimated as 6 years) |
Duration of Response (DOR) | DOR by investigator assessment. | Baseline to Study Completion (estimated as 6 years) |
Progression-free Survival 2 (PFS2) | PFS2 by investigator assessment. | Baseline to Study Completion (estimated as 6 years) |
Plasma Concentrations of Vepugratinib | PK samples are to be drawn every odd cycle while participant on study. | Cycle 1 Day 1 to Study completion (estimated as 90 months) |
Change from Baseline in Global Health Status/Quality of Life (QOL) and Physical Function Measured by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) | The EORTC QLQ-C30 is a validated self-reported general cancer questionnaire consisting of 30 items with a recall of the past 7 days. Response options range from 1) "very poor" to 7) "excellent." Higher scores represent better overall HRQoL. | Baseline to Study Completion (estimated as 6 years) |
Eligibility Criteria
Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
- Have histologically confirmed, unresectable locally advanced or metastatic urothelial cancer (mUC). Individuals with mixed histology other than small cell or neuroendocrine carcinoma are eligible if a urothelial component is present.
- Have a qualifying fibroblast growth factor receptor 3 (FGFR3) genetic alteration determined via molecular testing from a tumor or blood sample obtained at or any time after diagnosis of advanced or metastatic urothelial cancer.
- Have measurable disease by investigator assessment defined by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1
- Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2.
- Have adequate laboratory parameters
- Have received prior systemic therapy for locally advanced or metastatic urothelial cancer (mUC).
- Have any unresolved toxicities greater than Grade 1 Common Terminology Criteria for Adverse Events ([CTCAE] version 5.0) from prior neoadjuvant or adjuvant systemic therapy.
- Have ongoing sensory or motor neuropathy of Grade 2 or higher
- Have untreated or uncontrolled central nervous system (CNS) involvement or any history of leptomeningeal disease.
- Current evidence corneal keratopathy or retinal disorder confirmed by ocular examination at screening.
Eli Lilly and Company357 active trials to exploreStudy Central Contact
Contact: Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or, 1-317-615-4559, [email protected]
Contact: Physicians interested in becoming principal investigators please contact, [email protected]
268 Study Locations in 19 Countries
Box Hill Hospital, Box Hill, 3128, Australia
Iris Tung, Principal Investigator
Mater Misericordiae Limited, Brisbane, 4101, Australia
Niara Oliveira, Principal Investigator
Austin Health, Heidelberg, 3084, Australia
Contact, +61420381848
Andrew Weickhardt, Principal Investigator
Macquarie University, Macquarie University, 2109, Australia
Contact, 0402856430
Alison Zhang, Principal Investigator
Sir Charles Gairdner Hospital, Perth, 6009, Australia
Rajiv Shinde, Principal Investigator
Prince of Wales Hospital, Randwick, 2031, Australia
Elizabeth Hovey, Principal Investigator
Alabama
Clearview Cancer Institute, Huntsville, Alabama, 35805, United States
Contact, 256-705-4224
Marshall Schreeder, Principal Investigator
Arizona
The University of Arizona Cancer Center - North Campus, Tucson, Arizona, 85719, United States
Contact, 520-626-4703
Alejandro Recio Boiles, Principal Investigator
California
TRIO-US (Translational Research in Oncology-US), Los Angeles, California, 90024, United States
Brenda Williams, Principal Investigator
UCLA Hematology/Oncology - Santa Monica, Los Angeles, California, 90404, United States
Alexandra Drakaki, Principal Investigator
UCSF Medical Center at Mission Bay, San Francisco, California, 94158, United States
Contact, 773-837-0783
Vadim Koshkin, Principal Investigator
Hunt Cancer Institute, an Affiliate of Cedars-Sinai Cancer (TMPN), Torrance, California, 90505, United States
Contact, 310-750-3300
Hugo Hool, Principal Investigator
Colorado
AdventHealth Medical Group - Porter, Denver, Colorado, 80210, United States
Contact, 303-715-7030
Yousuf Gaffar, Principal Investigator
Colorado West Healthcare System - Grand Valley Oncology, Grand Junction, Colorado, 81505, United States
Contact, 970-644-4460
Jonathan King, Principal Investigator
Florida
AdventHealth Celebration, Celebration, Florida, 34747, United States
Contact, 407-303-2024
Guru Sonpavde, Principal Investigator
Idaho
St. Luke's Cancer Institute: Boise, Boise, Idaho, 83712, United States
Peyman Haghighat, Principal Investigator
Illinois
University of Illinois at Chicago, Chicago, Illinois, 60612, United States
Karine Tawagi, Principal Investigator
Indiana
Parkview Research Center at Parkview Regional Medical Center, Fort Wayne, Indiana, 46845, United States
Kushal Naha, Principal Investigator
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, 46202, United States
Tareq Salous, Principal Investigator
Franciscan Health, Indianapolis, Indiana, 46237, United States
Patrick Heckman, Principal Investigator
Kentucky
University of Kentucky Chandler Medical Center, Lexington, Kentucky, 40536, United States
Zin Myint, Principal Investigator
Louisiana
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, 70809, United States
Contact, 225-215-1185
Victor Lin, Principal Investigator
Maryland
Johns Hopkins Hospital, Baltimore, Maryland, 21287, United States
Jean Hoffman-Censits, Principal Investigator
Massachusetts
Massachusetts General Hospital, Boston, Massachusetts, 02114, United States
Contact, 617-724-4000
Xin Gao, Principal Investigator
Michigan
Karmanos Cancer Institute, Detroit, Michigan, 48201, United States
Yusra Shao, Principal Investigator
Missouri
Washington University, St Louis, Missouri, 63108, United States
Melissa Reimers, Principal Investigator
Nevada
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, 89148, United States
Ammar Yousif, Principal Investigator
New York
Icahn School of Medicine at Mount Sinai, New York, New York, 10029, United States
Matthew Galsky, Principal Investigator
Columbia University Irving Medical Center, New York, New York, 10032, United States
Alexander Wei, Principal Investigator
Memorial Sloan Kettering Cancer Center, New York, New York, 10065, United States
Contact, 646-888-4737
Gopakumar Iyer, Principal Investigator
Weill Cornell Medical College, New York, New York, 10065, United States
Contact, 317-217-9178
Rohit Jain, Principal Investigator
Ohio
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Columbus, Ohio, 43210, United States
Peng Wang, Principal Investigator
Oregon
Providence Portland Medical Center, Portland, Oregon, 97213, United States
Brendan Curti, Principal Investigator
Providence St. Vincent Medical Center, Portland, Oregon, 97225, United States
Brendan Curti, Principal Investigator
Kaiser Permanente Interstate Medical Office Central, Portland, Oregon, 97227, United States
Contact, 503-249-3315
Sandeep Mashru, Principal Investigator
Oregon Health and Science University, Portland, Oregon, 97239, United States
Ronald Ng, Principal Investigator
Pennsylvania
Lancaster General Hospital - Ann B Barshinger Cancer Institute, Lancaster, Pennsylvania, 17601, United States
Matthew Brennan, Principal Investigator
AHN Allegheny General Hospital, Pittsburgh, Pennsylvania, 15212, United States
Contact, 412-325-5700
Shifeng Mao, Principal Investigator
South Dakota
Avera Cancer Institute- Research, Sioux Falls, South Dakota, 57105, United States
Ryan Vaca, Principal Investigator
Tennessee
Tennessee Oncology Chattanooga, Chattanooga, Tennessee, 37404, United States
Kathryn Beckermann, Principal Investigator
Sarah Cannon Research Institute, Nashville, Tennessee, 37203, United States
SMO Sarah Cannon Research Inst., Principal Investigator
SCRI Oncology Partners, Nashville, Tennessee, 37203, United States
Benjamin Garmezy, Principal Investigator
Tennessee Oncology, Nashville, Tennessee, 37203, United States
Kathryn Beckermann, Principal Investigator
Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States
Alan Tan, Principal Investigator
Texas
USO-Texas Oncology-Central/South Texas, Austin, Texas, 78731, United States
Michael Lattanzi, Principal Investigator
World Research Link, Baytown, Texas, 77521, United States
Contact, 833-832-8328
Amir Rasheed, Principal Investigator
Parkland Health and Hospital System, Dallas, Texas, 75235, United States
Contact, 214-648-4180
Tian Zhang, Principal Investigator
UT Southwestern Medical Center, Dallas, Texas, 75390, United States
Contact, 214-648-4180
Tian Zhang, Principal Investigator
University of Texas MD Anderson Cancer Center, Houston, Texas, 77030-4009, United States
Arlene Siefker-Radtke, Principal Investigator
Nova Oncology, McAllen, Texas, 78504, United States
Contact, 281-944-3610
Raghad Muhsin Abdul Karim, MD, Principal Investigator
US Oncology Research Network, The Woodlands, Texas, 77380, United States
SMO Sarah Cannon Research Inst., Principal Investigator
USO - Texas Oncology - Northeast Texas, Tyler, Texas, 75702, United States
Donald Richards, Principal Investigator
Virginia
USO - Virginia Oncology Associates, Norfolk, Virginia, 23502, United States
Mark Fleming, Principal Investigator
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, 14784400, Brazil
Contact, 551733216637
Hadson Araujo, Principal Investigator
CPAM - Centro de Pesquisas da Amazônia, Belém, 66063-495, Brazil
Contact, 5591999809897
Bruno Fernandes, Principal Investigator
Oncocentro de Minas Gerais, Belo Horizonte, 30180-060, Brazil
Flavio Cárcano, Principal Investigator
Hospital Mario Penna, Belo Horizonte, 30380-472, Brazil
Graziella Martins, Principal Investigator
Hospital Tacchini, Bento Gonçalves, 95700-084, Brazil
ANDRE REIRIZ, Principal Investigator
Centro Integrado de Oncologia de Curitiba, Curitiba, 80810050, Brazil
Contact, 554130242421
Karina Vianna, Principal Investigator
IOP Pesquisa, Curitiba, 82305-100, Brazil
Ronald Kool, Principal Investigator
Centro Paraibano De Oncologia - Oncoclínicas, João Pessoa, 58030-080, Brazil
Juliana Fagundes, Principal Investigator
Hospital de Cancer de Londrina, Londrina, 86015-520, Brazil
Contact, +55 43 3379-2771
Mariana Kiara, Principal Investigator
Liga Norte Riograndense Contra o Câncer, Natal, 59062-000, Brazil
Contact, +5584991425228
Andrea Gomes, Principal Investigator
Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa, Porto Alegre, 90110-270, Brazil
Contact, 5133072943
Alan Azambuja, Principal Investigator
Hospital São Lucas da PUCRS, Porto Alegre, 90610-000, Brazil
Vinicius Goncalves, Principal Investigator
Hospital Nossa Senhora da Conceição, Porto Alegre, 91350-200, Brazil
Contact, +55 51 35160954
Gustavo Alves, Principal Investigator
Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rio de Janeiro, 20231-050, Brazil
pedro domingues, Principal Investigator
Instituto D'Or Pesquisa e Ensino, Rio de Janeiro, 22271-110, Brazil
Daniel Herchenhorn, Principal Investigator
Nucleo de Oncologia da Bahia, Salvador, 40170-110, Brazil
Contact, 557140097085
Andre Lima, Principal Investigator
Clinica Amo - Rio Vermelho, Salvador, 41950-640, Brazil
Contact, 557130218735
Augusto Mota, Principal Investigator
Instituto de Oncologia Saint Gallen, Santa Cruz do Sul, 96830-180, Brazil
Contact, 5551991898942
Bianca Correa Tabajara Weiss, Principal Investigator
Centro de Oncologia - CEON+ - Unidade São Caetano do Sul, São Caetano do Sul, 09541-270, Brazil
Suelen Martins, Principal Investigator
Instituto do Cancer Arnaldo Vieira de Carvalho, São Paulo, 01209-000, Brazil
Contact, +5511956598420
Patricia Marubayashi, Principal Investigator
Icesp - Instituto Do Câncer Do Estado de São Paulo, São Paulo, 01246-000, Brazil
Contact, 55 11 3893-2709
Jose Mauricio Mota, Principal Investigator
Hospital BP, São Paulo, 01321-001, Brazil
Fabio Schutz, Principal Investigator
Hospital Alemao Oswaldo Cruz, São Paulo, 01327-001, Brazil
Contact, 1135490665
Ariel Kann, Principal Investigator
Centro Paulista de Oncologia Clínica, São Paulo, 01452-000, Brazil
Contact, (17) 981090074
Denis Leonardo Fontes Jardim, Principal Investigator
IBCC - Núcleo de Pesquisa e Ensino, São Paulo, 04014-002, Brazil
Contact, 551144500360
Felipe José Cruz, Principal Investigator
Hamilton Health Sciences-Juravinski Cancer Centre, Hamilton, L8V5C2, Canada
Arani Sathiyapalan, Principal Investigator
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus, Québec, G1J 1Z4, Canada
Antoine Morin Coulombe, Principal Investigator
BC Cancer Vancouver, Vancouver, V5Z 4E6, Canada
Bernhard Eigl, Principal Investigator
Peking University First Hospital, Beijing, 100034, China
Contact, 010-64008229
Zhisong He, Principal Investigator
Peking University Third Hospital, Beijing, 100091, China
Shudong Zhang, Principal Investigator
Beijing Cancer hospital, Beijing, 100142, China
Jun Guo, Principal Investigator
Beijing GoBroad Hospital, Beijing, 102200, China
Chuanliang Cui, Principal Investigator
The First Hospital of Jilin University, Changchun, 100012, China
Ziling Liu, Principal Investigator
Xiangya Hospital Central South University, Changsha, 410008, China
Contact, 0731-84327918
minfeng chen, Principal Investigator
Hunan Cancer Hospital, Changsha, 410013, China
Shusuan JIANG, Principal Investigator
West China Hospital, Sichuan University, Chengdu, 610066, China
Peng Zhang, Principal Investigator
The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China
Contact, 023-89012012
Weiyang He, Principal Investigator
Chongqing University Cancer Hospital, Chongqing, 400030, China
Fang Yuan, Principal Investigator
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China
Contact, 13719007083
Yongda Liu, Principal Investigator
Zhujiang Hospital, Guangzhou, 510280, China
Manming Cao, Principal Investigator
Sun Yat-Sen University Cancer Centre, Guangzhou, 511400, China
Contact, 020-87343864
Yanxia Shi, Principal Investigator
Zhejiang Provincial People's Hospital, Hangzhou, 310014, China
Contact, 15158885167
xiaolong Qi, Principal Investigator
Sir Run Run Shaw Hospital, Hangzhou, 310016, China
Da Li, Principal Investigator
Zhejiang Cancer Hospital, Hangzhou, 310022, China
Jinchao Chen, Principal Investigator
Harbin Medical University Cancer Hospital, Harbin, 150081, China
Contact, 0451-86298104
Hui Chen, Principal Investigator
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210000, China
Hongqian Guo, Principal Investigator
Guangxi Medical University Affiliated Tumor Hospital, Nanning, 530200, China
Contact, 15877183968
Yong Tang, Principal Investigator
Ningbo First Hospital, Ningbo, 315010, China
Contact, 15958800971
Qi Ma, Principal Investigator
Renji Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, 200000, China
Contact, 862168383543
Wei Xue, Principal Investigator
Huashan Hospital, Fudan University, Shanghai, 200040, China
Haowen Jiang, Principal Investigator
Shanghai Tenth People's Hospital, Shanghai, 200072, China
Contact, 021-66301719
Xudong Yao, Principal Investigator
The Second Hospital of Tianjin Medical University, Tianjin, 300211, China
Hailong Hu, Principal Investigator
Tongji Hospital Tongji Medical,Science & Technology, Wuhan, 430030, China
Contact, 027-83363434
Shaogang Wang, Principal Investigator
Masarykuv onkologicky ustav, Brno, 656 53, Czechia
Contact, 420 543 132 216
Alexandr Poprach, Principal Investigator
Fakultni nemocnice Hradec Kralove, Hradec Králové, 500 05, Czechia
Contact, 420495832176
Jindrich Kopecky, Principal Investigator
Fakultni nemocnice Olomouc, Olomouc, 779 00, Czechia
Contact, +420 588 444 717
Hana Studentova, Principal Investigator
Fakultni nemocnice Kralovske Vinohrady, Prague, 10034, Czechia
Contact, 420267162837
Jan Dvorak, Principal Investigator
Fakultni Thomayerova nemocnice, Prague, 14059, Czechia
Contact, 420 728177828
Michaela Matouskova, Principal Investigator
Fakultni nemocnice Motol, Prague, 150 06, Czechia
Contact, 420734236410
Tomas Buchler, Principal Investigator
Aalborg Universitetshospital, Syd, Aalborg, 9000, Denmark
Contact, 004597661410
Andreas Carus, Principal Investigator
Aarhus Universitetshospital, Skejby, Aarhus, 8200, Denmark
Mads Agerbaek, Principal Investigator
Rigshospitalet, Copenhagen, 2100, Denmark
Contact, 4535458403
Helle Pappot, Principal Investigator
Herlev and Gentofte Hospital, Copenhagen, 2730, Denmark
Contact, 4538681079
Line Dohn, Principal Investigator
Næstved Sygehus, Næstved, 4700, Denmark
Dorthe Yakymenko, Principal Investigator
Institut de Cancérologie de l'Ouest, Angers, 49055, France
Contact, 33241352700
Sophie Abadie-Lacourtoisie, Principal Investigator
CHU de Bordeaux Hop St ANDRE, Bordeaux, 33075, France
Contact, +33556794708
Marine Gross-Goupil, Principal Investigator
Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, 33076, France
Diego Teyssonneau, Principal Investigator
CHRU de Brest, Brest, 29609, France
Benjamin Auberger, Principal Investigator
Centre François Baclesse, Caen, 14076, France
Florence Joly-Lobbedez, Principal Investigator
Centre Oscar Lambret, Lille, 59020, France
Contact, 0033 (0)320009757
Yaovi AMELA, Principal Investigator
Centre Leon Berard, Lyon Cedex08, 69373, France
Contact, 33478782643
Aude Flechon, Principal Investigator
Institut Paoli-Calmettes, Marseille, 13273, France
Gwenaelle Gravis, Principal Investigator
Centre Hospitalier Universitaire de Nîmes - Institut de Cancérologie du Gard - Hôpital Universitaire Carém -T, Nîmes, 30029, France
Leticia Aptecar, Principal Investigator
Centre Hospitalier Lyon Sud, Pierre-Bénite, 69310, France
Contact, 33478864324
Denis Maillet, Principal Investigator
Oncopole Claudius Regaud, Toulouse, 31059, France
Damien POUESSEL, Principal Investigator
Gustave Roussy, Villejuif, 94800, France
Contact, 33142115276
Yohann Loriot, Principal Investigator
Helios Klinikum Bad Saarow, Bad Saarow, 15526, Germany
Contact, 0049 33631 73466
Tobias Klatte, Principal Investigator
Charité Universitaetsmedizin Berlin - Campus Mitte, Berlin, 10117, Germany
Contact, 004930450615137
Maria De Santis, Principal Investigator
Evangelisches Krankenhaus Bielefeld - Johannesstift, Bielefeld, 33611, Germany
Contact, 052177275750
Florian Weissinger, Principal Investigator
Johanniter-Krankenhaus, Bonn, 53113, Germany
Contact, 00492285432168
Carsten Ohlmann, Principal Investigator
Studienzentrum Bayenthal Urologische Partnerschaft Köln, Cologne, 50968, Germany
Contact, 0049221362025
Jorg Klier, Principal Investigator
Universitaetsklinikum Carl Gustav Carus, Technischen Universitaet Dresden, Dresden, 01307, Germany
Contact, 00493514584425
Severine Banek, Principal Investigator
Urologicum Duisburg Fachärztesozietät - Walsum, Duisburg, 47179, Germany
Contact, +49 203 5003040
Eva Hellmis, Principal Investigator
Universitaetsklinikum Duesseldorf, Düsseldorf, 40225, Germany
Contact, 492118119353
Guenter Niegisch, Principal Investigator
Universitaetsklinikum Erlangen, Erlangen, 91054, Germany
Contact, +49 (0)9131 8223122
Peter Goebell, Principal Investigator
Universitaetsklinikum Essen, Essen, 45122, Germany
Contact, +492017232637
Viktor Gruenwald, Principal Investigator
Krankenhaus Nordwest GmbH, Frankfurt, 60488, Germany
Contact, 496976013917
Inga Peters, Principal Investigator
Universitaetsklinikum Freiburg, Freiburg im Breisgau, 79106, Germany
Markus Grabbert, Principal Investigator
Universitätsmedizin Greifswald, Greifswald, 17489, Germany
Contact, 00493834865985
Cindy Roennau, Principal Investigator
Universitaetsklinikum Hamburg-Eppendorf, Hamburg, 20246, Germany
Contact, 040-7410-57673
Gunhild Von Amsberg, Principal Investigator
NCT, Heidelberg, 69120, Germany
Stefanie Zschaebitz, Principal Investigator
InVO Institut für Versorgungsforschung in der Onkologie, Koblenz, 56068, Germany
Contact, +49261921569325
Christoph Lutz, Principal Investigator
Universitätsklinikum Schleswig-Holstein, Lübeck, 23538, Germany
Contact, 045150043691
Axel Merseburger, Principal Investigator
Klinikum Rechts Der Isar Der Technischen Universität München, Munich, 81675, Germany
Contact, 498941402522
Margitta Retz, Principal Investigator
Universitätsklinikum Münster - Albert Schweitzer Campus, Münster, 48149, Germany
Martin Boegemann, Principal Investigator
Klinikum Nürnberg Nord, Nuremberg, 90419, Germany
Contact, + 49 911 398 3085
Marinela Augustin, Principal Investigator
Studienpraxis Urologie, Nürtingen, 72622, Germany
Contact, 4915201622246
Tilman Todenhöfer, Principal Investigator
Universitätsmedizin Rostock, Rostock, 18057, Germany
Contact, +49 381 494 7801
Angelika Borkowetz, Principal Investigator
Universitaetsklinikum Tuebingen, Tübingen, 72076, Germany
Eva Erne, Principal Investigator
Universitaetsklinikum Ulm, Ulm, 89081, Germany
Contact, 4973150058036
Friedemann Zengerling, Principal Investigator
Universitaetsklinikum Wuerzburg, Würzburg, 97080, Germany
Anna Seitz, Principal Investigator
Semmelweis Egyetem, Budapest, 1082, Hungary
Peter Nyirady, Principal Investigator
Országos Onkológiai Intézet, Budapest, 1122, Hungary
Contact, 3612248600
Lajos Geczi, Principal Investigator
Debreceni Egyetem Klinikai Kozpont, Debrecen, 4032, Hungary
Contact, 3652255840
Peter Arkosy, Principal Investigator
Szabolcs Szatmár Bereg Vármegyei Oktatókórház, Nyíregyháza, 4400, Hungary
Contact, 003642599700 EXT 2334
Ágnes Wéber, Principal Investigator
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ, Szeged, 6725, Hungary
Aniko Maraz, Principal Investigator
Instituto Tumori Giovanni Paolo II, Bari, 70124, Italy
Contact, +39 0805555391
Marica Gentile, Principal Investigator
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, 20133, Italy
Contact, 0390223903028
Giuseppe Procopio, Principal Investigator
Ospedale San Raffaele, Milan, 20132, Italy
Contact, +390226435789
Andrea Necchi, Principal Investigator
Azienda Ospedaliera Universitaria Federico II, Napoli, 80131, Italy
Contact, +393404166268
Luigi Formisano, Principal Investigator
Istituto Oncologico Veneto IRCCS, Padua, 35128, Italy
Contact, +390423732137
Marco Maruzzo, Principal Investigator
Azienda Ospedaliera Universitaria Pisana, Pisa, 56126, Italy
Luca Galli, Principal Investigator
Fondazione Policlinico Universitario Agostino Gemelli, Roma, 00168, Italy
Contact, 390630154838
Roberto Iacovelli, Principal Investigator
Istituto Nazionale Tumori Regina Elena, Rome, 00144, Italy
Fabio Calabro, Principal Investigator
National Cancer Center Hospital, Chūōku, 104-0045, Japan
Contact, 81120023812
Tatsunori Shimoi, Principal Investigator
Kyushu University Hospital, Fukuoka, 812-8582, Japan
Contact, 81120023812
Takashi Matsumoto, Principal Investigator
Hirosaki University Hospital, Hirosaki, 036-8563, Japan
Contact, 81120023812
Shingo Hatakeyama, Principal Investigator
Kanazawa University Hospital, Kanazawa, 920-8641, Japan
Contact, 81120023812
Kouji Izumi, Principal Investigator
National Cancer Center Hospital East, Kashiwa, 277-8577, Japan
Contact, 81120023812
Nobuaki Matsubara, Principal Investigator
St. Marianna University Hospital, Kawasaki, 216-8511, Japan
Contact, 81120023812
Eiji Kikuchi, Principal Investigator
Kagawa University Hospital, Kita-ku, 761-0701, Japan
Contact, 81120023812
Rikiya Taoka, Principal Investigator
Kobe City Medical Center General Hospital, Kobe, 650-0047, Japan
Contact, 81120023812
Toshinari Yamasaki, Principal Investigator
The Cancer Institute Hospital of JFCR, Kōtoku, 135-8550, Japan
Contact, 81120023812
Yuji Miura, Principal Investigator
Kyoto University Hospital, Kyoto, 606-8507, Japan
Contact, 81120023812
Akihiro Hamada, Principal Investigator
National Hospital Organization Shikoku Cancer Center, Matsuyama, 791-0280, Japan
Contact, 81120023812
Katsuyoshi Hashine, Principal Investigator
Aichi Cancer Center Hospital, Nagoya, 464-8681, Japan
Contact, 81120023812
Hiromichi Ebi, Principal Investigator
Niigata University Medical & Dental Hospital, Niigata, 951-8520, Japan
Contact, 81120023812
Tsutomu Anraku, Principal Investigator
Osaka International Cancer Institute, Osaka, 541-8567, Japan
Contact, 81120023812
Masashi Nakayama, Principal Investigator
Gunma Prefectural Cancer Center, Otashi, 373-8550, Japan
Contact, 81120023812
Masaru Hasumi, Principal Investigator
Hokkaido University Hospital, Sapporo, 060-8648, Japan
Contact, 81120023812
Haruka Miyata, Principal Investigator
Tohoku University Hospital, Sendai, 980-8574, Japan
Contact, 81120023812
Takuma Sato, Principal Investigator
Iwate Medical University Hospital, Shiwa-gun Yahaba-cho, 028-3695, Japan
Contact, 81120023812
Wataru Obara, Principal Investigator
Tokushima University Hospital, Tokushima, 770-8503, Japan
Contact, 81120023812
junya furukawa, Principal Investigator
Tsukuba University Hospital, Tsukuba, 305-8576, Japan
Contact, 81120023812
Yoshiyuki Nagumo, Principal Investigator
Amsterdam UMC, locatie VUmc, Amsterdam, 1081 HV, Netherlands
Contact, +31(0)20-4444321
Jens Voortman, Principal Investigator
Amphia Ziekenhuis, locatie Breda Molengracht, Breda, 4818 CK, Netherlands
Contact, +31 76 595 5146
Hans Westgeest, Principal Investigator
Radboudumc, Nijmegen, 6525 GA, Netherlands
Contact, +31 (0)24 3610353
Mira Franken, Principal Investigator
Erasmus Medisch Centrum, Rotterdam, 3015 GD, Netherlands
Contact, +31618842777
Debbie Robbrecht, Principal Investigator
IN VIVO, Bydgoszcz, 85-048, Poland
Contact, 48888455614
Anna Krause, Principal Investigator
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie, Koszalin, 75-581, Poland
Contact, 48502204953
Mariusz Kwiatkowski, Principal Investigator
Pratia MCM Krakow, Krakow, 30-727, Poland
Contact, 48 505 169 040
Anna Drosik Kwasniewska, Principal Investigator
AIDPORT Sp. z o.o., Skórzewo, 60-185, Poland
Piotr Tomczak, Principal Investigator
GYNCENTRUM Szpital, Sosnowiec, 41-208, Poland
Sylwia Szablowska-Siwik, Principal Investigator
Luxmed Onkologia sp. z o. o., Warsaw, 01-748, Poland
Pawel Morawski, Principal Investigator
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie, Warsaw, 02-781, Poland
Contact, 48225462433
Pawel Wiechno, Principal Investigator
WSD MEDI, Warsaw, 02-786, Poland
Anna Wasko Grabowska, Principal Investigator
Medical Concierge Centrum Medyczne, Warsaw, 02-798, Poland
Contact, 602300992
Piotr Radziszewski, Principal Investigator
Szpital Grochowski im. dr med. Rafała Masztaka SPZOZ, Warsaw, 04-073, Poland
Contact, 48 22 5152 591
Iwona Skoneczna, Principal Investigator
Wojskowy Instytut Medyczny Państwowy Instytut Badawczy, Warsaw, 04-141, Poland
Szymon Borowiec, Principal Investigator
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu, Wrocaw, 50-556, Poland
Anna Kolodziej, Principal Investigator
National Cancer Center, Goyang-si, 10408, South Korea
Ho Kyung Seo, Principal Investigator
Chungnam national university hospital, Junggu, 35015, South Korea
Hyo Jin Lee, Principal Investigator
Gachon University Gil Medical Center, Namdong-gu, 21565, South Korea
Joo-Hwan Park, Principal Investigator
Seoul National University Bundang Hospital, Seongnam, 13620, South Korea
Contact, 820317877842
Eun Hee Jung, Principal Investigator
Seoul National University Hospital, Seoul, 03080, South Korea
Jeonghwan Youk, Principal Investigator
Severance Hospital, Yonsei University Health System, Seoul, 03722, South Korea
Contact, 82222288138
Sang Joon Shin, Principal Investigator
Asan Medical Center, Seoul, 05505, South Korea
Contact, 82-2-3010-3266
Inkeun Park, Principal Investigator
Samsung Medical Center, Seoul, 06351, South Korea
Contact, 82-2-3410-3459
Se Hoon Park, Principal Investigator
The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, 06591, South Korea
Contact, 82-10-9056-6116
In-Ho Kim, Principal Investigator
Ewha Womans University Mokdong Hospital, Seoul, 07985, South Korea
Jungmin Jo, Principal Investigator
Hospital Infanta Cristina, Badajoz, 06006, Spain
Contact, 924218040
Marta Gonzalez Cordero, Principal Investigator
Institut Català d'Oncologia (ICO) - Badalona, Badalona, 08916, Spain
Contact, 34 934978925
Albert Font Pous, Principal Investigator
OSI Ezkerraldea-Enkarterri-Cruces - Hospital Universitario Cruces, Barakaldo, 48903, Spain
Ricardo Fernández Rodríguez, Principal Investigator
Hospital Universitari Vall d'Hebron, Barcelona, 08035, Spain
Contact, 932746000 x 4350
Rafael Morales Barrera, Principal Investigator
Hospital Clínic de Barcelona, Barcelona, 08036, Spain
Contact, 34 932275402
Oscar Reig Torras, Principal Investigator
Hospital de la Santa Creu i Sant Pau, Barcelona, 08041, Spain
Contact, 34935565638
Jose Pablo Maroto Rey, Principal Investigator
Hospital Universitario Reina Sofia, Córdoba, 14004, Spain
MARIA JOSE MENDEZ VIDAL, Principal Investigator
Hospital General Universitario de Elche, Elche, 03202, Spain
Federico Jose Vazquez Mazon, Principal Investigator
Institut Català d'Oncologia (ICO) - Girona, Girona, 17007, Spain
Contact, 34972225834
Nuria Sala Gonzalez, Principal Investigator
Instituto Catalan de Oncologia - Hospital Duran i Reynals, Hospitalet, 08907, Spain
Contact, +34 932603261
Irene Ortiz Rubio, Principal Investigator
Hospital Insular de Gran Canaria, Las Palmas de Gran Canaria, 35016, Spain
Alfonso Gómez de Liaño Lista, Principal Investigator
Hospital La Princesa, Madrid, 28006, Spain
Contact, +34915202200
Patricia Toquero Diez, Principal Investigator
Hospital General Universitario Gregorio Marañon, Madrid, 28009, Spain
Contact, 34914265238
Jose Arranz Arija, Principal Investigator
MD Anderson Cancer Center, Madrid, 28033, Spain
Lucrecia Ruiz, Principal Investigator
Hospital Universitario Ramón y Cajal, Madrid, 28034, Spain
Contact, (+34) 913368263
Pablo Gajate Borau, Principal Investigator
Hospital Clinico San Carlos, Madrid, 28040, Spain
Contact, 913307545
Javier Puente Vazquez, Principal Investigator
Hospital Universitario 12 de Octubre, Madrid, 28041, Spain
Contact, 0034 91 390 83 39
Daniel Castellano Gauna, Principal Investigator
Hospital Universitario La Paz, Madrid, 28046, Spain
Contact, 917277516
Alvaro Pinto Marin, Principal Investigator
H.R.U Málaga - Hospital General, Málaga, 29011, Spain
Contact, 951308130
Alvaro Montesa Pino, Principal Investigator
Complejo Hospitalario de Navarra, Pamplona, 31009, Spain
Contact, 8.00 - 15.00
Nuria Lainez Milagro, Principal Investigator
Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón, 28223, Spain
Contact, +34914521987
ELENA ALMAGRO CASADO, Principal Investigator
Hospital Universitari Sant Joan de Reus, Reus, 43204, Spain
Marc Grifoll Escoda, Principal Investigator
Hospital Universitario Marqués de Valdecilla, Santander, 39008, Spain
Contact, 607552230
Ignacio Duran Martinez, Principal Investigator
CHUS - Hospital Clinico Universitario, Santiago de Compostela, 15706, Spain
Contact, 34981950512
Urbano Anido Herranz, Principal Investigator
Hospital Universitario Virgen Del Rocio, Seville, 41013, Spain
Contact, 34955013068
Begona Perez Valderrama, Principal Investigator
Hospital Arnau de Vilanova, Valencia, 46015, Spain
Contact, 679370073
Jose Garcia Sanchez, Principal Investigator
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, 807, Taiwan
Wen-Jeng Wu, Principal Investigator
Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung Niao Sung Dist, 83301, Taiwan
Contact, 886-972919696
Yu-Li Su, Principal Investigator
China Medical University Hospital, Taichung, 404332, Taiwan
Contact, +886422052121
Chao-Hsiang Chang, Principal Investigator
Taichung Veterans General Hospital, Taichung, 407, Taiwan
Jian-Ri Li, Principal Investigator
National Cheng Kung University Hospital, Tainan, 704, Taiwan
Contact, 0980971870
Wen-Pin Su, Principal Investigator
Chi Mei Medical Center, Tainan, 71004, Taiwan
Nai-Wen Kang, Principal Investigator
Chi Mei Hospital - Liouying Branch, Tainan, 73657, Taiwan
Yen-Hsun Chen, Principal Investigator
National Taiwan University Hospital, Taipei, 10002, Taiwan
Yu-Chieh Tsai, Principal Investigator
National Taiwan University Cancer Center (NTUCC), Taipei, 106, Taiwan
Ying-Chun Shen, Principal Investigator
Taipei Veterans General Hospital, Taipei, 11217, Taiwan
Contact, 886228757519-323
Yi-Hsiu Huang, Principal Investigator
Chang Gung Medical Foundation-Linkou Branch, Taoyuan District, 333, Taiwan
Contact, 886-3-3281200
See-Tong Pang, Principal Investigator
Adana Medical Park Seyhan Hastanesi, Adana, 01140, Turkey (Türkiye)
Contact, 905325005269
Ali Besen, Principal Investigator
Sakarya University School of Medicine, Adapazarı, 54100, Turkey (Türkiye)
Contact, +90 5054785576
Ilhan Hacibekiroglu, Principal Investigator
Ankara University Health Practice and Research Hospitals, Ankara, 06100, Turkey (Türkiye)
Contact, 00903125957321
Yuksel Urun, Principal Investigator
Ankara Bilkent Şehir Hastanesi, Ankara, 06800, Turkey (Türkiye)
Contact, 905555306271
Mehmet Ali Nahit Sendur, Principal Investigator
Antalya Egitim ve Arastırma Hastanesi, Antalya, 07100, Turkey (Türkiye)
Contact, 905336488217
Derya KIVRAK SALIM, Principal Investigator
Memorial Diyarbakır Hastanesi, Diyarbakır, 21070, Turkey (Türkiye)
Contact, 90 5337677131
Muhammet kaplan, Principal Investigator
Trakya University, Edirne, 22030, Turkey (Türkiye)
Contact, 90 5334364678
Muhammet Hacioglu, Principal Investigator
Gaziantep Universitesi Sahinbey Arastirma ve Uygulama Hastanesi, Gaziantep, 27310, Turkey (Türkiye)
Contact, 05065118207
tulay kus, Principal Investigator
Dr. Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, 34890, Turkey (Türkiye)
Mahmut Gumus, Principal Investigator
Marmara Universitesi Pendik Egitim Arastirma Hastanesi, Istanbul, 34899, Turkey (Türkiye)
Contact, 905433389339
Murat Sari, Principal Investigator
zmir Katip Çelebi Üniversitesi Atatürk Eitim Ve Aratrma Hastanesi, Izmir, 35360, Turkey (Türkiye)
Contact, 905324078648
Ahmet Alacacioglu, Principal Investigator
Huddersfield Royal Infirmary, Huddersfield, HD3 3EA, United Kingdom
Ursula Hofmann, Principal Investigator
St Bartholomew's Hospital, London, EC1A 7BE, United Kingdom
Contact, 02078828494
Thomas Powles, Principal Investigator
University College London Hospital, London, NW1 2PG, United Kingdom
Ursula McGovern, Principal Investigator
Royal Marsden Hospital (Sutton), London, SM2 5PT, United Kingdom
Contact, +44 (0) 2086613529
Robert Huddart, Principal Investigator
Royal Marsden Hospital (Chelsea), London, SW3 6JJ, United Kingdom
Contact, +44 (0) 2086613529
Robert Huddart, Principal Investigator
The Christie NHS Foundation Trust, Manchester, M20 4BX, United Kingdom
Contact, 01614468409
Yee Pei Song, Principal Investigator
Weston Park Hospital, Sheffield, S10 2SJ, United Kingdom
Syed Hussain, Principal Investigator