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L'essai clinique NCT07495774 (INSPIRE-PPH) pour Hypertension pulmonaire est en recrutement. Consultez la vue en carte du Radar des Essais Cliniques et les outils de découverte par IA pour tous les détails, ou posez vos questions ici. | ||
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Insights Into Pediatric Pulmonary Hypertension: A Real-World Registry of Epidemiology and Outcomes (INSPIRE-PPH) 450 Données vie réelle Pédiatrique Adolescent Observationnel
Les détails de l'essai clinique sont principalement disponibles en anglais. Cependant, l'IA Trial Radar peut vous aider ! Cliquez simplement sur 'Expliquer l'étude' pour voir et discuter des informations sur l'étude dans la langue sélectionnée.
L'essai clinique NCT07495774 (INSPIRE-PPH) est une étude observationnel pour Hypertension pulmonaire. Son statut actuel est : en recrutement. L'étude a débuté le 4 janvier 2006 et vise à recruter 450 participants. Dirigée par Guangdong Provincial People's Hospital, l'étude devrait être terminée d'ici le 31 décembre 2035. Les données du site ClinicalTrials.gov ont été mises à jour pour la dernière fois le 27 mars 2026.
Résumé succinct
Pediatric pulmonary hypertension (PH) shares similarities with PH in adulthood, but specific differences still require unique approaches. Despite major advances, risk scores for pediatric PH still need to be validated, and targeted drug therapies in pediatric populations remain under-studied. Consequently, there is a great need for comprehensive real-world longitudinal data of pediatric PH.
The INSPIRE-PH registry i...
Afficher plusTitre officiel
Insights Into Epidemiology, Management, and Outcomes of Pediatric Pulmonary Hypertension: The INSPIRE-PH Multicenter Real-World Registry
Pathologies
Hypertension pulmonaireAutres identifiants de l'étude
- INSPIRE-PPH
- INSPIRE-PPH-Registry
Numéro NCT
Date de début (réel)
2006-01-04
Dernière mise à jour publiée
2026-03-27
Date de fin (estimée)
2035-12-31
Inscription (estimée)
450
Type d'étude
Observationnel
Statut
En recrutement
Mots clés
pediatric
pulmonary hypertension
real-world
epidemiology
outcome
pulmonary hypertension
real-world
epidemiology
outcome
Critère principal d'évaluation
Critère secondaire d'évaluation
| Critères d'évaluation | Description de la mesure | Période |
|---|---|---|
death | From enrollment to the event, assessed through study completion (target follow-up duration of 10 years; extended follow-up available for earlier enrollees) | |
transplantation | From enrollment to the event, assessed through study completion (target follow-up duration of 10 years; extended follow-up available for earlier enrollees) |
| Critères d'évaluation | Description de la mesure | Période |
|---|---|---|
PH-related hospitalization | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
atrial septostomy | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
Potts shunt | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
clinical worsening | Clinical worsening is defined as the first occurrence of death, transplantation, hospitalization for PH, atrial septostomy or Potts shunt, with need for escalation of PH-targeted therapy, or worsening functional status. | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) |
decline in WHO functional class | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) |
Assistant à la participation
Critères d'éligibilité
Âges éligibles
Enfant, Adulte
Sexes éligibles
Tous
- Children and adolescents aged <18 years at diagnosis
- Diagnosed pulmonary hypertension (PH) according to the prevailing diagnostic criteria at the time of enrollment
- Enrollment in the registry at participating centers
- Provision of informed consent by patients and/or legal guardians
- Availability for longitudinal follow-up
- Inability to confirm PH diagnosis due to insufficient clinical or hemodynamic data
- Refusal or inability to provide informed consent
Guangdong Provincial People's HospitalPartie responsable de l'étude
Zhi-Cheng Jing, MD, Investigateur principal, Prof., Guangdong Provincial People's Hospital
Contact central de l'étude
Contact: Jie-Xin Zhang, Dr., +86-18629534652, [email protected]
1 Centres de l'étude dans 1 pays
Guangdong
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, 510080, China
En recrutement