Radar des Essais Cliniques

Renal artery anatomy failures include:

1. Renal artery diameter <4mm or treatment length <20mm;
2. Renal artery stenosis >50% or renal aneurysm on either side;
3. A history of renal artery intervention, including balloon angioplasty or stenting or RDN;

Glomerular filtration rate (eGFR) <45mL/min/1.73m2 (MDRD formula);

History of hospitalization for hypertensive crisis in the past year;

During the screening and lead-in period, the patient used antihypertensive drugs other than the standard antihypertensive drugs prescribed in this study protocol;

Nocturnal sleep apnea syndrome requires mechanical ventilation (such as tracheostomy);

Those who have or are currently suffering from the following diseases or conditions:

1. Primary pulmonary hypertension (moderate to severe);
2. Type I diabetes;
3. History of any cerebrovascular events (eg, stroke, transient cerebral ischemic event, cerebrovascular accident) within 3 months;
4. History of any serious cardiovascular event within 3 months (eg, myocardial infarction, CABG, acute heart failure requiring hospitalization (NYHA III-IV), unstable angina attack);
5. Factors that interfere with blood pressure measurement in any case (eg, patients with severe peripheral vascular disease, abdominal aortic aneurysm, bleeding disorders such as thrombocytopenia, hemophilia, severe anemia);
6. Arranged or planned surgery or cardiovascular intervention within the next 6 months;
7. Patients with malignant tumors and end-stage diseases who survival period is less than 1year;

Patients with secondary hypertension.

Patients who are deemed inappropriate to participate in this trial by other investigators.