ट्रायल रडार AI | ||
|---|---|---|
क्लिनिकल ट्रायल NCT06150989 (BLOOM) के लिए हृदयवाहिनी रोगों, हृदय रोग जोखिम कारक वर्तमान में भर्ती जारी है। सभी विवरणों के लिए क्लिनिकल ट्रायल रडार कार्ड दृश्य और AI खोज उपकरण देखें, या यहाँ कुछ भी पूछें। | ||
एक परीक्षण फ़िल्टर मानदंडों से मेल खाता है
कार्ड दृश्य
Black Women's Life Experience On Cardiovascular Health Via Ongoing Monitoring (BLOOM)
चिकित्सा परीक्षण का विवरण मुख्य रूप से अंग्रेजी में उपलब्ध है। हालाँकि, ट्रायल रडार AI मदद कर सकता है! बस 'परीक्षण समझाएं' पर क्लिक करें और अपनी चुनी हुई भाषा में परीक्षण की जानकारी देखें और चर्चा करें।
क्लिनिकल परीक्षण NCT06150989 (BLOOM) एक प्रेक्षणीय चिकित्सकीय अध्ययन है जो हृदयवाहिनी रोगों, हृदय रोग जोखिम कारक से जुड़ा हुआ है। परीक्षण वर्तमान में भर्ती जारी चल रहा है। इसकी शुरुआत 4 मार्च 2024 को हुई थी, और इसमें कुल 80 प्रतिभागियों के नामांकन की योजना है। The University of Texas at Arlington इस परीक्षण का नेतृत्व कर रहे हैं और इसके 1 मार्च 2026 तक पूरा होने की उम्मीद है। ClinicalTrials.gov वेबसाइट पर यह जानकारी 29 अप्रैल 2025 को अंतिम बार अपडेट की गई थी।
संक्षिप्त सारांश
This pilot study uses a state-of-the-science combination of remote behavioral monitoring, real-time experience sampling, in-lab physiological assessments, and extraction of neighborhood-level characteristics to (1) Examine the impact of daily experience (i.e., racial discrimination, affective states, stress) on health behaviors (i.e., physical activity, sedentary behavior, sleep) at the intrapersonal level among Black women; (2) Test the association between daily behaviors and impairments in biomarkers associated with vascular function/health (i.e., augmented systemic inflammation and oxidative stress, impaired peripheral/cerebral vascular function, increased large artery stiffness), as well as the impact of daily experience on the relationship between behaviors and vascular function; and (3) Explore the influence of neighborhood-level characteristics (i.e., social environment factors: i.e., neighborhood income and poverty, racial composition; and built environment context, such as park density and walkability) on daily experience and health behaviors.
आधिकारिक शीर्षक
A Biobehavioral Approach to Understand the Multilevel Determinants of Cardiovascular Health in Black Women
चिकित्सीय स्थितियाँ
हृदयवाहिनी रोगोंहृदय रोग जोखिम कारकप्रकाशन
इस नैदानिक परीक्षण के बारे में प्रकाशित वैज्ञानिक लेख और शोध पत्र:अन्य अध्ययन आईडी
- BLOOM
- 2023-0344
NCT नंबर
अध्ययन प्रारंभ तिथि (वास्तविक)
2024-03-04
अंतिम अद्यतन प्रकाशित
2025-04-29
अध्ययन की समाप्ति तिथि (अनुमानित)
2026-03
नामांकन (अनुमानित)
80
अध्ययन प्रकार
प्रेक्षणीय
स्थिति
भर्ती जारी
समूह/हस्तक्षेप
| प्रतिभागी समूह/हाथ | हस्तक्षेप/इलाज |
|---|---|
Observational Group Black women enrolled in this study will complete a series of lab-based assessments that evaluate their vascular health, followed by a 10-day free-living monitoring period with mobile and wearable devices. | पर्यवेक्षण समूह All participants will go through a series of lab-based assessments to evaluate their vascular health. These assessments include: heart rhythm/rate, blood pressure, large blood vessel flow, central aortic blood pressure and pulse wave velocity, brain blood flow, carbon dioxide concentration, flow mediated dilation/blood vessel responsiveness, breathing rate, and cerebral vasomotor reactivity. In addition, venous blood sample will be taken to identify biomarkers that are associated with elevating blood pressure and decreasing blood flow.
The 10-day monitoring period includes a wrist-worn activity tracker and a blood pressure monitor bracelet; a smartphone app that will prompt surveys up to 6 times a day to assess behaviors, social/physical context, mood/stress, and experience of racial discrimination/microaggression. Participants will also collect saliva samples on three consecutive days during the 10-day monitoring period. |
प्राथमिक परिणाम माप
द्वितीयक परिणाम माप
| परिणाम माप | माप विवरण | समय सीमा |
|---|---|---|
Macrovascular function | Macrovascular function will be assessed as brachial artery vasodilation following a period of suprasystolic cuff occlusion. Microvascular function will be assessed as the % change in blood velocity from baseline following cuff release. | Day 1 |
Arterial Stiffness | An appropriately sized blood pressure cuff will be placed on the upper arm and central (aortic) and peripheral (arm) blood pressure will be assessed using the non-invasive SphygmoCor Xcel device. This device provides measurement of augmentation index (in percentage), which is an indicator of arterial stiffness. | Day 1 |
Blood Flow Measurements (Large Blood Vessels) | A Doppler ultrasound probe will be used to measure blood flow in the upper arm, leg, and/or neck (e.g., brachial artery, femoral artery, and carotid artery, respectively). | Day 1 |
Blood Flow Measurements (Cerebral Blood Vessels) | Cerebral blood flow will be indexed from the velocity of blood flowing through the middle cerebral artery. This will be accomplished using transcranial Doppler ultrasound. | Day 1 |
| परिणाम माप | माप विवरण | समय सीमा |
|---|---|---|
Physical activity | Daily physical activity level will be assessed via a wrist-worn accelerometer. | Day 2 to Day 11 |
पात्रता मानदंड
अध्ययन के लिए पात्र आयु
वयस्क
अध्ययन के लिए न्यूनतम आयु
18 Years
अध्ययन के लिए पात्र लिंग
महिला
स्वस्थ स्वयंसेवकों को स्वीकार करता है
हाँ
- born and identified as female;
- between 18-49 years old;
- self-identify as Black or African American;
- not currently pregnant;
- ownership of a smartphone with Internet access;
- able to speak and read English
- diagnosed hypertension, cardiovascular, respiratory, metabolic, and/or neurological disorders;
- functional limitations or health issues that preclude physical activity;
- currently taking medications for thyroid function or psychological conditions such as depression, anxiety, and mood disorders;
- current use of oral or inhalant corticosteroids for asthma;
- have regularly smoked within the last 2 years.
The University of Texas at ArlingtonAmerican Heart Associationअध्ययन उत्तरदायी पक्ष
Yue Liao, मुख्य अन्वेषक, Assistant Professor, The University of Texas at Arlington
कोई संपर्क डेटा नहीं।
1 1 देशों में अध्ययन स्थल
Texas
The University of Texas at Arlington, Arlington, Texas, 76010, United States
Physical Activity and Wearable Sensors Lab, संपर्क, 8172728524, [email protected]
Yue Liao, PhD, MPH, मुख्य अन्वेषक
भर्ती जारी