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Exercise-induced Hypoalgesia and Proprioceptive Changes, Comparing Isometric to Isotonic Neck Exercises

募集中
治験(臨床試験)の詳細は主に英語で提供されています。しかし、治験レーダーAIが支援できます!「治験を説明」をクリックして、選択した言語で試験情報を表示し、議論してください。
治験番号 NCT06465394介入研究 臨床試験 で、運動 に関するものです。現在は 募集中 で、2024年8月12日 から開始しています。40 名の参加者 の募集が計画されています。この治験は University of South Dakota によって主催され、2025年5月5日 に完了予定です。ClinicalTrials.gov からの最新更新日は 2024年12月6日 です。
概要
Exercised induced hypoalgesia (EIH) (reduction in pain) after exercise has been studied in the literature, but no comparisons have been made specifically looking at different types of exercise (isometric/dynamic moving through a range of motion with resistance versus isotonic/applying static resistance to a joint not moving) with neck muscle strengthening. This study will explore to see if one form of exercise is superior to the other in providing EIH.

Another benefit of exercise is improving proprioception (knowing where our body is in space). Again no specific investigation has been done comparing isometric versus isotonic exercises for neck muscles.

Both of these exercises are often prescribed in physical therapy so further understanding the benefits of them can help improve the prescription of exercises for patients.

詳細説明
After consent has been obtained, participants will be asked the screening questions to confirm eligibility for the study. The researcher will then ask the participants demographic questions and record the responses for age, gender, racial category, and handedness. Odd-numbered participants will perform isometric exercises first and then isotonic exercises on the second day. Even numbered participants will perform isotonic exercises first and then isometric exercises on the second day. There will be 2-3 days between each test period. Testing each time will have participants do baseline measurements for pain pressure threshold (PPT) and proprioception (JPE), exercise protocol, and then retest PPT and JPE post exercise.

Pain pressure threshold testing consists of measuring the distance between C7 and the distal aspect of the acromion while the participant is seated. If possible, the shirt will be removed for men, or the neck color pulled to the side for females. If unable to move the shirt to the side, the testing can be done over the clothing. The mid-way point will be marked with a pen or other method to indicate the location on the upper trap muscle where the PPT testing will be performed on both the right and left sides. Utilization of a pressure algometer will be used for testing with a 1 cm2 rubber tip. The pressure algometer tip will be placed on the mark of the midpoint of the upper trap previously measured and marked. Pressure is slowly applied until the participant reports a change from pressure to pain and says "STOP". At the moment the participant says stop, the pressure is stopped, and the recording is measured. There will be 3 tests with PPT on both right and left alternating between each side with testing.

Proprioception is measured by the joint position error (JPE) test. This test requires the patient to place a headlamp equipped with a laser pointer. They will be seated in a chair facing a wall with the JPE target on the wall. The subject is to sit with their head in a normal resting state, looking straight ahead. The target is adjusted to the participant's baseline. The participant is instructed to get a "sense" of this position. The participant then moves their head/neck to the right or left, returning to their resting position. The subject then closes their eyes and completed 6 trials of turning their head to the right and 6 trials to the left. The researcher will assist them in recentering to their start position each time before the next rotation of the head/neck.

Once the baseline PPT and JPE are measured, the subjects will go through the exercise protocol.

Isometric test protocol. Participants will be asked to perform the exercise at a moderate exercise level (3/10 on the mRPE scale provided to them). They will complete a 1, 10-second isometric hold to their hand dominant side (if ambidextrous, the side the participant would report as the most dominant side) to allow them to find their "moderate" intensity level. The participant will then take a 2-minute rest before beginning the exercise routine and will be instructed to keep a consistent resistance level during the exercise bout. During the exercise, the subjects will hold the rotation contraction for 10 seconds, take a 2-second rest, complete this 5 times, and then change to the left side. They will do this for 3 sets of right and left. Researchers will time the exercises and give verbal instructions to make sure they are performing for the appropriate amount of time and rest periods. After completing the exercise protocol, they will complete the PPT and JPE tests in the same way as was done for baseline measurement.

Isotonic test protocol. Participants will be asked to perform the exercise at a moderate exercise level (3/10) on the mRPE scale provided to them). They will complete 2 reps using the red rubber band resistance on the 'NecksLevel' neck strengthening device, moving through a full range of motion toward their hand-dominant side as they will do in the isometric test. After completing the 2 test reps, they will be asked if they would like to increase or decrease the resistance to be at a moderate level. The new resistance level or staying the same level will then be done for 3 more reps to ensure they are at a moderate level. The participants will then take a 2-minute rest before beginning the exercise routine. The resistance level will stay at the participant's selected moderate level during the entire testing unless they need to stop due to pain or difficulty completing the exercise. During the exercise, the participants will be rotating to the right first at a pace of 1 second for concentric contraction to full rotation and 1 second for eccentric contraction, returning the head to the neutral position. The participant will continue this pace to complete 5 repetitions and then take a 2-second rest before continuing this sequence 5 times (a total of 25 reps) before switching and doing left rotation in the same fashion. This will be done for a total of 3 sets for both right and left rotation. The use of a metronome will be used along with the researcher's verbal instructions and cueing to maintain the proper sequence and timing of the exercise. After completing the exercise protocol, they will complete the PPT and JPE tests in the same way as was done for baseline measurement.

公式タイトル

Exercise-induced Hypoalgesia and Proprioceptive Changes, Comparing Isometric to Isotonic Neck Exercises

疾患/病気
運動
その他の研究識別子
  • IRB-24-100
NCT番号
開始日
2024-08-12
最終更新日
2024-12-06
終了予定日
2025-05-05
目標参加者数
40
試験の種類
介入研究
治験の相・段階
該当なし
状況
募集中
主目的
治療
割付方法
無作為化
介入モデル
交叉・クロスオーバー
盲検化
単盲検
群(アーム)/介入
参加グループ/群介入/治療法
実薬対照薬Isometric Exercise
Isometric test protocol. Participants will be asked to perform the exercise at a moderate exercise level (3/10 on the mRPE scale provided to them). They will complete a 1, 10-second isometric hold to their hand dominant side (if ambidextrous, the side the participant would report as the most dominant side) to allow them to find their "moderate" intensity level. The participant will then take a 2-minute rest before beginning the exercise routine and will be instructed to keep a consistent resistance level during the exercise bout. During the exercise, the subjects will hold the rotation contraction for 10 seconds, take a 2-second rest, complete this 5 times, and then change to the left side. They will do this for 3 sets of right and left. Researchers will time the exercises and give verbal instructions to make sure they are performing for the appropriate amount of time and rest periods.
運動
Neck exercises in a cross over design that the participants will do both types of interventions with a washout period inbetween.
実薬対照薬Isotonic Exercise
The resistance level will stay at the participant's selected moderate level during the entire testing unless they need to stop due to pain or difficulty completing the exercise. During the exercise, the participants will be rotating to the right first at a pace of 1 second for concentric contraction to full rotation and 1 second for eccentric contraction, returning the head to the neutral position. The participant will continue this pace to complete 5 repetitions and then take a 2-second rest before continuing this sequence 5 times (a total of 25 reps) before switching and doing left rotation in the same fashion. This will be done for a total of 3 sets for both right and left rotation. The use of a metronome will be used along with the researcher's verbal instructions and cueing to maintain the proper sequence and timing of the exercise.
運動
Neck exercises in a cross over design that the participants will do both types of interventions with a washout period inbetween.
主要評価項目
評価指標指標の説明時間枠
PPT
Pain Pressure Threshold with use of algometer
Pre post measure before and after exercise session taking approximately 10 minutes
副次評価項目
評価指標指標の説明時間枠
JPE
Joint position error utilizing measurement in cm from baseline
Pre post measure before and after exercise session taking approximately 10 minutes
適格基準

対象年齢
成人
試験の最低年齢
18 Years
対象性別
全て
健康なボランティアを受け入れる
はい
  • 18-64 years old,
  • all genders,
  • healthy individuals with no neck pain

  • Medical restrictions to physical activity
  • History of chronic pain (pain > 3 months) or current acute neck pain
  • Unable to refrain from alcohol, pain medications, and vigorous exercise 24 hours prior to testing
University of South Dakota logoUniversity of South Dakota
責任者
Kory Zimney, PT, DPT, PhD, 研究責任者, Associate Professor, University of South Dakota
試験中央連絡先
連絡先: Kory J Zimney, PhD, 6056586373, [email protected]
1 1カ国の場所

South Dakota

University of South Dakota, Vermillion, South Dakota, 57069, United States
Kory Zimney, DPT, PhD, 連絡先, 605-658-6373, [email protected]
募集中