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治験 NCT07218380 (FORAGER-2)（対象：移行細胞癌腫、膀胱腫瘍、腫瘍転移）は募集未定です。詳細は治験レーダーのタイル表示と AI 発見ツールで確認するか、ここで質問してください。 | ||
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イーライリリーA Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract (FORAGER-2)
治験(臨床試験)の詳細は主に英語で提供されています。しかし、治験レーダーAIが支援できます！「治験を説明」をクリックして、選択した言語で試験情報を表示し、議論してください。
治験番号 NCT07218380 (FORAGER-2) は 治療 の研究で、移行細胞癌腫、膀胱腫瘍、腫瘍転移 に関するものです。この 第III相・第三段階 介入研究 臨床試験 は現在 募集未定 で、2025年11月1日 に開始予定です。450 名の参加者 の募集が計画されています。この治験は イーライリリー によって主催され、2033年5月1日 に完了予定です。ClinicalTrials.gov からの最新更新日は 2025年11月24日 です。
概要
The purpose of this study is to test a new medicine, vepugratinib, in comparison with placebo, to see if it is safe and can help people with a bladder cancer that is advanced or has spread.
Vepugratinib or placebo will be administered in combination with enfortumab vedotin and pembrolizumab.
Study participation could last up to approximately 6 years.
公式タイトル
FORAGER-2: A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Vepugratinib Combined With Enfortumab Vedotin and Pembrolizumab in Adults With Untreated Locally Advanced or Metastatic Urothelial Carcinoma With an FGFR3 Genetic Alteration
疾患／病気
移行細胞癌腫膀胱腫瘍腫瘍転移その他の研究識別子
- FORAGER-2
- 27333
- J4G-MC-JZVD (その他の識別子) (Eli Lilly and Company)
- 2025-522855-25-00 (EU試験（CTIS）番号)
NCT番号
開始日
2025-11
最終更新日
2025-11-24
終了予定日
2033-05
目標参加者数
450
試験の種類
介入研究
治験の相・段階
第III相・第三段階
状況
募集未定
キーワード
FGFR3
Advanced Urothelial Carcinoma
Metastatic Urothelial Carcinoma
Advanced Urothelial Carcinoma
Metastatic Urothelial Carcinoma
主目的
治療
割付方法
無作為化
介入モデル
並行割当
盲検化
二重盲検
群（アーム）／介入
| 参加グループ/群 | 介入/治療法 |
|---|---|
実験的Vepugratinib + EV + Pembrolizumab (Safety Lead In) Vepugratinib administered orally with EV + pembrolizumab administered IV | Vepugratinib Administered orally EV Administered by IV infusion Pembrolizumab Administered by IV infusion |
実験的Vepugratinib + Enfortumab Vedotin (EV) + Pembrolizumab Vepugratinib administered orally, and EV + pembrolizumab administered by intravenous (IV) infusion. | Vepugratinib Administered orally EV Administered by IV infusion Pembrolizumab Administered by IV infusion |
プラセボ対照薬Placebo + EV + Pembrolizumab Placebo administered orally, and EV + pembrolizumab administered by IV infusion. | プラセボ Administered orally EV Administered by IV infusion Pembrolizumab Administered by IV infusion |
主要評価項目
副次評価項目
| 評価指標 | 指標の説明 | 時間枠 |
|---|---|---|
Number of participants with treatment-related adverse events related to vepugratinib in combination with EV and pembrolizumab | From baseline up to 90 months | |
Safety Lead-in: Overall Response Rate (ORR) | ORR by Investigator Assessment. | From baseline up to 90 months |
Progression-free Survival (PFS) | PFS by blinded independent committee review (BICR). | Baseline to Study Completion (estimated as 6 years) |
| 評価指標 | 指標の説明 | 時間枠 |
|---|---|---|
Safety Lead-in: Disease Control Rate (DCR) | DCR by investigator assessment. | From baseline up to the end of Cycle 2 (each Cycle is 21 days) |
Safety Lead-in: Time to Response (TTR) | TTR by investigator assessment. | From baseline up to 90 months |
Overall Survival (OS) | Baseline to Study Completion (estimated as 6 years) | |
Objective Response Rate (ORR) by BICR | Baseline to Study Completion (estimated as 6 years) | |
Duration of Response (DoR) | DOR by BICR. | Baseline to Study Completion (estimated as 6 years) |
Progression-free Survival (PFS) | PFS by investigator assessment. | Baseline to Study Completion (estimated as 6 years) |
Objective Response Rate (ORR) | Percentage of Participants who Achieve a Best Overall Response (BOR) of Complete Response (CR) or Partial Response (PR)ORR by investigator assessment | Baseline to Study Completion (estimated as 6 years) |
Duration of Response (DOR) | DOR by investigator assessment. | Baseline to Study Completion (estimated as 6 years) |
Progression-free Survival 2 (PFS2) | PFS2 by investigator assessment. | Baseline to Study Completion (estimated as 6 years) |
Plasma Concentrations of Vepugratinib | PK samples are to be drawn every odd cycle while participant on study. | Cycle 1 Day 1 to Study completion (estimated as 90 months) |
Change from Baseline in Global Health Status/Quality of Life (QOL) and Physical Function Measured by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) | The EORTC QLQ-C30 is a validated self-reported general cancer questionnaire consisting of 30 items with a recall of the past 7 days. Response options range from 1) "very poor" to 7) "excellent." Higher scores represent better overall HRQoL. | Baseline to Study Completion (estimated as 6 years) |
適格基準
対象年齢
成人, 高齢者
試験の最低年齢
18 Years
対象性別
全て
- Have histologically confirmed, unresectable locally advanced or metastatic urothelial cancer (mUC). Individuals with mixed histology other than small cell or neuroendocrine carcinoma are eligible if a urothelial component is present.
- Have a qualifying fibroblast growth factor receptor 3 (FGFR3) genetic alteration determined via molecular testing from a tumor or blood sample obtained at or any time after diagnosis of advanced or metastatic urothelial cancer.
- Have measurable disease by investigator assessment defined by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1
- Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2.
- Have adequate laboratory parameters
- Have received prior systemic therapy for locally advanced or metastatic urothelial cancer (mUC).
- Have any unresolved toxicities greater than Grade 1 Common Terminology Criteria for Adverse Events ([CTCAE] version 5.0) from prior neoadjuvant or adjuvant systemic therapy.
- Have ongoing sensory or motor neuropathy of Grade 2 or higher
- Have untreated or uncontrolled central nervous system (CNS) involvement or any history of leptomeningeal disease.
- Current evidence corneal keratopathy or retinal disorder confirmed by ocular examination at screening.
イーライリリー357 件のアクティブな治験を探索試験中央連絡先
連絡先: Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or, 1-317-615-4559, [email protected]
連絡先: Physicians interested in becoming principal investigators please contact, [email protected]
268 19カ国の場所
National Cancer Center Hospital, Chūōku, 104-0045, Japan
連絡先, 81120023812
Tatsunori Shimoi, 研究責任者
Kyushu University Hospital, Fukuoka, 812-8582, Japan
連絡先, 81120023812
Takashi Matsumoto, 研究責任者
Hirosaki University Hospital, Hirosaki, 036-8563, Japan
連絡先, 81120023812
Shingo Hatakeyama, 研究責任者
Kanazawa University Hospital, Kanazawa, 920-8641, Japan
連絡先, 81120023812
Kouji Izumi, 研究責任者
National Cancer Center Hospital East, Kashiwa, 277-8577, Japan
連絡先, 81120023812
Nobuaki Matsubara, 研究責任者
St. Marianna University Hospital, Kawasaki, 216-8511, Japan
連絡先, 81120023812
Eiji Kikuchi, 研究責任者
Kagawa University Hospital, Kita-ku, 761-0701, Japan
連絡先, 81120023812
Rikiya Taoka, 研究責任者
Kobe City Medical Center General Hospital, Kobe, 650-0047, Japan
連絡先, 81120023812
Toshinari Yamasaki, 研究責任者
The Cancer Institute Hospital of JFCR, Kōtoku, 135-8550, Japan
連絡先, 81120023812
Yuji Miura, 研究責任者
Kyoto University Hospital, Kyoto, 606-8507, Japan
連絡先, 81120023812
Akihiro Hamada, 研究責任者
National Hospital Organization Shikoku Cancer Center, Matsuyama, 791-0280, Japan
連絡先, 81120023812
Katsuyoshi Hashine, 研究責任者
Aichi Cancer Center Hospital, Nagoya, 464-8681, Japan
連絡先, 81120023812
Hiromichi Ebi, 研究責任者
Niigata University Medical & Dental Hospital, Niigata, 951-8520, Japan
連絡先, 81120023812
Tsutomu Anraku, 研究責任者
Osaka International Cancer Institute, Osaka, 541-8567, Japan
連絡先, 81120023812
Masashi Nakayama, 研究責任者
Gunma Prefectural Cancer Center, Otashi, 373-8550, Japan
連絡先, 81120023812
Masaru Hasumi, 研究責任者
Hokkaido University Hospital, Sapporo, 060-8648, Japan
連絡先, 81120023812
Haruka Miyata, 研究責任者
Tohoku University Hospital, Sendai, 980-8574, Japan
連絡先, 81120023812
Takuma Sato, 研究責任者
Iwate Medical University Hospital, Shiwa-gun Yahaba-cho, 028-3695, Japan
連絡先, 81120023812
Wataru Obara, 研究責任者
Tokushima University Hospital, Tokushima, 770-8503, Japan
連絡先, 81120023812
junya furukawa, 研究責任者
Tsukuba University Hospital, Tsukuba, 305-8576, Japan
連絡先, 81120023812
Yoshiyuki Nagumo, 研究責任者
Alabama
Clearview Cancer Institute, Huntsville, Alabama, 35805, United States
連絡先, 256-705-4224
Marshall Schreeder, 研究責任者
Arizona
The University of Arizona Cancer Center - North Campus, Tucson, Arizona, 85719, United States
連絡先, 520-626-4703
Alejandro Recio Boiles, 研究責任者
California
TRIO-US (Translational Research in Oncology-US), Los Angeles, California, 90024, United States
Brenda Williams, 研究責任者
UCLA Hematology/Oncology - Santa Monica, Los Angeles, California, 90404, United States
Alexandra Drakaki, 研究責任者
UCSF Medical Center at Mission Bay, San Francisco, California, 94158, United States
連絡先, 773-837-0783
Vadim Koshkin, 研究責任者
Hunt Cancer Institute, an Affiliate of Cedars-Sinai Cancer (TMPN), Torrance, California, 90505, United States
連絡先, 310-750-3300
Hugo Hool, 研究責任者
Colorado
AdventHealth Medical Group - Porter, Denver, Colorado, 80210, United States
連絡先, 303-715-7030
Yousuf Gaffar, 研究責任者
Colorado West Healthcare System - Grand Valley Oncology, Grand Junction, Colorado, 81505, United States
連絡先, 970-644-4460
Jonathan King, 研究責任者
Florida
AdventHealth Celebration, Celebration, Florida, 34747, United States
連絡先, 407-303-2024
Guru Sonpavde, 研究責任者
Idaho
St. Luke's Cancer Institute: Boise, Boise, Idaho, 83712, United States
Peyman Haghighat, 研究責任者
Illinois
University of Illinois at Chicago, Chicago, Illinois, 60612, United States
Karine Tawagi, 研究責任者
Indiana
Parkview Research Center at Parkview Regional Medical Center, Fort Wayne, Indiana, 46845, United States
Kushal Naha, 研究責任者
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, 46202, United States
Tareq Salous, 研究責任者
Franciscan Health, Indianapolis, Indiana, 46237, United States
Patrick Heckman, 研究責任者
Kentucky
University of Kentucky Chandler Medical Center, Lexington, Kentucky, 40536, United States
Zin Myint, 研究責任者
Louisiana
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, 70809, United States
連絡先, 225-215-1185
Victor Lin, 研究責任者
Maryland
Johns Hopkins Hospital, Baltimore, Maryland, 21287, United States
Jean Hoffman-Censits, 研究責任者
Massachusetts
Massachusetts General Hospital, Boston, Massachusetts, 02114, United States
連絡先, 617-724-4000
Xin Gao, 研究責任者
Michigan
Karmanos Cancer Institute, Detroit, Michigan, 48201, United States
Yusra Shao, 研究責任者
Missouri
Washington University, St Louis, Missouri, 63108, United States
Melissa Reimers, 研究責任者
Nevada
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, 89148, United States
Ammar Yousif, 研究責任者
New York
Icahn School of Medicine at Mount Sinai, New York, New York, 10029, United States
Matthew Galsky, 研究責任者
Columbia University Irving Medical Center, New York, New York, 10032, United States
Alexander Wei, 研究責任者
Memorial Sloan Kettering Cancer Center, New York, New York, 10065, United States
連絡先, 646-888-4737
Gopakumar Iyer, 研究責任者
Weill Cornell Medical College, New York, New York, 10065, United States
連絡先, 317-217-9178
Rohit Jain, 研究責任者
Ohio
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Columbus, Ohio, 43210, United States
Peng Wang, 研究責任者
Oregon
Providence Portland Medical Center, Portland, Oregon, 97213, United States
Brendan Curti, 研究責任者
Providence St. Vincent Medical Center, Portland, Oregon, 97225, United States
Brendan Curti, 研究責任者
Kaiser Permanente Interstate Medical Office Central, Portland, Oregon, 97227, United States
連絡先, 503-249-3315
Sandeep Mashru, 研究責任者
Oregon Health and Science University, Portland, Oregon, 97239, United States
Ronald Ng, 研究責任者
Pennsylvania
Lancaster General Hospital - Ann B Barshinger Cancer Institute, Lancaster, Pennsylvania, 17601, United States
Matthew Brennan, 研究責任者
AHN Allegheny General Hospital, Pittsburgh, Pennsylvania, 15212, United States
連絡先, 412-325-5700
Shifeng Mao, 研究責任者
South Dakota
Avera Cancer Institute- Research, Sioux Falls, South Dakota, 57105, United States
Ryan Vaca, 研究責任者
Tennessee
Tennessee Oncology Chattanooga, Chattanooga, Tennessee, 37404, United States
Kathryn Beckermann, 研究責任者
Sarah Cannon Research Institute, Nashville, Tennessee, 37203, United States
SMO Sarah Cannon Research Inst., 研究責任者
SCRI Oncology Partners, Nashville, Tennessee, 37203, United States
Benjamin Garmezy, 研究責任者
Tennessee Oncology, Nashville, Tennessee, 37203, United States
Kathryn Beckermann, 研究責任者
Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States
Alan Tan, 研究責任者
Texas
USO-Texas Oncology-Central/South Texas, Austin, Texas, 78731, United States
Michael Lattanzi, 研究責任者
World Research Link, Baytown, Texas, 77521, United States
連絡先, 833-832-8328
Amir Rasheed, 研究責任者
Parkland Health and Hospital System, Dallas, Texas, 75235, United States
連絡先, 214-648-4180
Tian Zhang, 研究責任者
UT Southwestern Medical Center, Dallas, Texas, 75390, United States
連絡先, 214-648-4180
Tian Zhang, 研究責任者
University of Texas MD Anderson Cancer Center, Houston, Texas, 77030-4009, United States
Arlene Siefker-Radtke, 研究責任者
Nova Oncology, McAllen, Texas, 78504, United States
連絡先, 281-944-3610
Raghad Muhsin Abdul Karim, MD, 研究責任者
US Oncology Research Network, The Woodlands, Texas, 77380, United States
SMO Sarah Cannon Research Inst., 研究責任者
USO - Texas Oncology - Northeast Texas, Tyler, Texas, 75702, United States
Donald Richards, 研究責任者
Virginia
USO - Virginia Oncology Associates, Norfolk, Virginia, 23502, United States
Mark Fleming, 研究責任者
Box Hill Hospital, Box Hill, 3128, Australia
Iris Tung, 研究責任者
Mater Misericordiae Limited, Brisbane, 4101, Australia
Niara Oliveira, 研究責任者
Austin Health, Heidelberg, 3084, Australia
連絡先, +61420381848
Andrew Weickhardt, 研究責任者
Macquarie University, Macquarie University, 2109, Australia
連絡先, 0402856430
Alison Zhang, 研究責任者
Sir Charles Gairdner Hospital, Perth, 6009, Australia
Rajiv Shinde, 研究責任者
Prince of Wales Hospital, Randwick, 2031, Australia
Elizabeth Hovey, 研究責任者
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, 14784400, Brazil
連絡先, 551733216637
Hadson Araujo, 研究責任者
CPAM - Centro de Pesquisas da Amazônia, Belém, 66063-495, Brazil
連絡先, 5591999809897
Bruno Fernandes, 研究責任者
Oncocentro de Minas Gerais, Belo Horizonte, 30180-060, Brazil
Flavio Cárcano, 研究責任者
Hospital Mario Penna, Belo Horizonte, 30380-472, Brazil
Graziella Martins, 研究責任者
Hospital Tacchini, Bento Gonçalves, 95700-084, Brazil
ANDRE REIRIZ, 研究責任者
Centro Integrado de Oncologia de Curitiba, Curitiba, 80810050, Brazil
連絡先, 554130242421
Karina Vianna, 研究責任者
IOP Pesquisa, Curitiba, 82305-100, Brazil
Ronald Kool, 研究責任者
Centro Paraibano De Oncologia - Oncoclínicas, João Pessoa, 58030-080, Brazil
Juliana Fagundes, 研究責任者
Hospital de Cancer de Londrina, Londrina, 86015-520, Brazil
連絡先, +55 43 3379-2771
Mariana Kiara, 研究責任者
Liga Norte Riograndense Contra o Câncer, Natal, 59062-000, Brazil
連絡先, +5584991425228
Andrea Gomes, 研究責任者
Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa, Porto Alegre, 90110-270, Brazil
連絡先, 5133072943
Alan Azambuja, 研究責任者
Hospital São Lucas da PUCRS, Porto Alegre, 90610-000, Brazil
Vinicius Goncalves, 研究責任者
Hospital Nossa Senhora da Conceição, Porto Alegre, 91350-200, Brazil
連絡先, +55 51 35160954
Gustavo Alves, 研究責任者
Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rio de Janeiro, 20231-050, Brazil
pedro domingues, 研究責任者
Instituto D'Or Pesquisa e Ensino, Rio de Janeiro, 22271-110, Brazil
Daniel Herchenhorn, 研究責任者
Nucleo de Oncologia da Bahia, Salvador, 40170-110, Brazil
連絡先, 557140097085
Andre Lima, 研究責任者
Clinica Amo - Rio Vermelho, Salvador, 41950-640, Brazil
連絡先, 557130218735
Augusto Mota, 研究責任者
Instituto de Oncologia Saint Gallen, Santa Cruz do Sul, 96830-180, Brazil
連絡先, 5551991898942
Bianca Correa Tabajara Weiss, 研究責任者
Centro de Oncologia - CEON+ - Unidade São Caetano do Sul, São Caetano do Sul, 09541-270, Brazil
Suelen Martins, 研究責任者
Instituto do Cancer Arnaldo Vieira de Carvalho, São Paulo, 01209-000, Brazil
連絡先, +5511956598420
Patricia Marubayashi, 研究責任者
Icesp - Instituto Do Câncer Do Estado de São Paulo, São Paulo, 01246-000, Brazil
連絡先, 55 11 3893-2709
Jose Mauricio Mota, 研究責任者
Hospital BP, São Paulo, 01321-001, Brazil
Fabio Schutz, 研究責任者
Hospital Alemao Oswaldo Cruz, São Paulo, 01327-001, Brazil
連絡先, 1135490665
Ariel Kann, 研究責任者
Centro Paulista de Oncologia Clínica, São Paulo, 01452-000, Brazil
連絡先, (17) 981090074
Denis Leonardo Fontes Jardim, 研究責任者
IBCC - Núcleo de Pesquisa e Ensino, São Paulo, 04014-002, Brazil
連絡先, 551144500360
Felipe José Cruz, 研究責任者
Hamilton Health Sciences-Juravinski Cancer Centre, Hamilton, L8V5C2, Canada
Arani Sathiyapalan, 研究責任者
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus, Québec, G1J 1Z4, Canada
Antoine Morin Coulombe, 研究責任者
BC Cancer Vancouver, Vancouver, V5Z 4E6, Canada
Bernhard Eigl, 研究責任者
Peking University First Hospital, Beijing, 100034, China
連絡先, 010-64008229
Zhisong He, 研究責任者
Peking University Third Hospital, Beijing, 100091, China
Shudong Zhang, 研究責任者
Beijing Cancer hospital, Beijing, 100142, China
Jun Guo, 研究責任者
Beijing GoBroad Hospital, Beijing, 102200, China
Chuanliang Cui, 研究責任者
The First Hospital of Jilin University, Changchun, 100012, China
Ziling Liu, 研究責任者
Xiangya Hospital Central South University, Changsha, 410008, China
連絡先, 0731-84327918
minfeng chen, 研究責任者
Hunan Cancer Hospital, Changsha, 410013, China
Shusuan JIANG, 研究責任者
West China Hospital, Sichuan University, Chengdu, 610066, China
Peng Zhang, 研究責任者
The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China
連絡先, 023-89012012
Weiyang He, 研究責任者
Chongqing University Cancer Hospital, Chongqing, 400030, China
Fang Yuan, 研究責任者
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China
連絡先, 13719007083
Yongda Liu, 研究責任者
Zhujiang Hospital, Guangzhou, 510280, China
Manming Cao, 研究責任者
Sun Yat-Sen University Cancer Centre, Guangzhou, 511400, China
連絡先, 020-87343864
Yanxia Shi, 研究責任者
Zhejiang Provincial People's Hospital, Hangzhou, 310014, China
連絡先, 15158885167
xiaolong Qi, 研究責任者
Sir Run Run Shaw Hospital, Hangzhou, 310016, China
Da Li, 研究責任者
Zhejiang Cancer Hospital, Hangzhou, 310022, China
Jinchao Chen, 研究責任者
Harbin Medical University Cancer Hospital, Harbin, 150081, China
連絡先, 0451-86298104
Hui Chen, 研究責任者
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210000, China
Hongqian Guo, 研究責任者
Guangxi Medical University Affiliated Tumor Hospital, Nanning, 530200, China
連絡先, 15877183968
Yong Tang, 研究責任者
Ningbo First Hospital, Ningbo, 315010, China
連絡先, 15958800971
Qi Ma, 研究責任者
Renji Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, 200000, China
連絡先, 862168383543
Wei Xue, 研究責任者
Huashan Hospital, Fudan University, Shanghai, 200040, China
Haowen Jiang, 研究責任者
Shanghai Tenth People's Hospital, Shanghai, 200072, China
連絡先, 021-66301719
Xudong Yao, 研究責任者
The Second Hospital of Tianjin Medical University, Tianjin, 300211, China
Hailong Hu, 研究責任者
Tongji Hospital Tongji Medical,Science & Technology, Wuhan, 430030, China
連絡先, 027-83363434
Shaogang Wang, 研究責任者
Masarykuv onkologicky ustav, Brno, 656 53, Czechia
連絡先, 420 543 132 216
Alexandr Poprach, 研究責任者
Fakultni nemocnice Hradec Kralove, Hradec Králové, 500 05, Czechia
連絡先, 420495832176
Jindrich Kopecky, 研究責任者
Fakultni nemocnice Olomouc, Olomouc, 779 00, Czechia
連絡先, +420 588 444 717
Hana Studentova, 研究責任者
Fakultni nemocnice Kralovske Vinohrady, Prague, 10034, Czechia
連絡先, 420267162837
Jan Dvorak, 研究責任者
Fakultni Thomayerova nemocnice, Prague, 14059, Czechia
連絡先, 420 728177828
Michaela Matouskova, 研究責任者
Fakultni nemocnice Motol, Prague, 150 06, Czechia
連絡先, 420734236410
Tomas Buchler, 研究責任者
Aalborg Universitetshospital, Syd, Aalborg, 9000, Denmark
連絡先, 004597661410
Andreas Carus, 研究責任者
Aarhus Universitetshospital, Skejby, Aarhus, 8200, Denmark
Mads Agerbaek, 研究責任者
Rigshospitalet, Copenhagen, 2100, Denmark
連絡先, 4535458403
Helle Pappot, 研究責任者
Herlev and Gentofte Hospital, Copenhagen, 2730, Denmark
連絡先, 4538681079
Line Dohn, 研究責任者
Næstved Sygehus, Næstved, 4700, Denmark
Dorthe Yakymenko, 研究責任者
Institut de Cancérologie de l'Ouest, Angers, 49055, France
連絡先, 33241352700
Sophie Abadie-Lacourtoisie, 研究責任者
CHU de Bordeaux Hop St ANDRE, Bordeaux, 33075, France
連絡先, +33556794708
Marine Gross-Goupil, 研究責任者
Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, 33076, France
Diego Teyssonneau, 研究責任者
CHRU de Brest, Brest, 29609, France
Benjamin Auberger, 研究責任者
Centre François Baclesse, Caen, 14076, France
Florence Joly-Lobbedez, 研究責任者
Centre Oscar Lambret, Lille, 59020, France
連絡先, 0033 (0)320009757
Yaovi AMELA, 研究責任者
Centre Leon Berard, Lyon Cedex08, 69373, France
連絡先, 33478782643
Aude Flechon, 研究責任者
Institut Paoli-Calmettes, Marseille, 13273, France
Gwenaelle Gravis, 研究責任者
Centre Hospitalier Universitaire de Nîmes - Institut de Cancérologie du Gard - Hôpital Universitaire Carém -T, Nîmes, 30029, France
Leticia Aptecar, 研究責任者
Centre Hospitalier Lyon Sud, Pierre-Bénite, 69310, France
連絡先, 33478864324
Denis Maillet, 研究責任者
Oncopole Claudius Regaud, Toulouse, 31059, France
Damien POUESSEL, 研究責任者
Gustave Roussy, Villejuif, 94800, France
連絡先, 33142115276
Yohann Loriot, 研究責任者
Helios Klinikum Bad Saarow, Bad Saarow, 15526, Germany
連絡先, 0049 33631 73466
Tobias Klatte, 研究責任者
Charité Universitaetsmedizin Berlin - Campus Mitte, Berlin, 10117, Germany
連絡先, 004930450615137
Maria De Santis, 研究責任者
Evangelisches Krankenhaus Bielefeld - Johannesstift, Bielefeld, 33611, Germany
連絡先, 052177275750
Florian Weissinger, 研究責任者
Johanniter-Krankenhaus, Bonn, 53113, Germany
連絡先, 00492285432168
Carsten Ohlmann, 研究責任者
Studienzentrum Bayenthal Urologische Partnerschaft Köln, Cologne, 50968, Germany
連絡先, 0049221362025
Jorg Klier, 研究責任者
Universitaetsklinikum Carl Gustav Carus, Technischen Universitaet Dresden, Dresden, 01307, Germany
連絡先, 00493514584425
Severine Banek, 研究責任者
Urologicum Duisburg Fachärztesozietät - Walsum, Duisburg, 47179, Germany
連絡先, +49 203 5003040
Eva Hellmis, 研究責任者
Universitaetsklinikum Duesseldorf, Düsseldorf, 40225, Germany
連絡先, 492118119353
Guenter Niegisch, 研究責任者
Universitaetsklinikum Erlangen, Erlangen, 91054, Germany
連絡先, +49 (0)9131 8223122
Peter Goebell, 研究責任者
Universitaetsklinikum Essen, Essen, 45122, Germany
連絡先, +492017232637
Viktor Gruenwald, 研究責任者
Krankenhaus Nordwest GmbH, Frankfurt, 60488, Germany
連絡先, 496976013917
Inga Peters, 研究責任者
Universitaetsklinikum Freiburg, Freiburg im Breisgau, 79106, Germany
Markus Grabbert, 研究責任者
Universitätsmedizin Greifswald, Greifswald, 17489, Germany
連絡先, 00493834865985
Cindy Roennau, 研究責任者
Universitaetsklinikum Hamburg-Eppendorf, Hamburg, 20246, Germany
連絡先, 040-7410-57673
Gunhild Von Amsberg, 研究責任者
NCT, Heidelberg, 69120, Germany
Stefanie Zschaebitz, 研究責任者
InVO Institut für Versorgungsforschung in der Onkologie, Koblenz, 56068, Germany
連絡先, +49261921569325
Christoph Lutz, 研究責任者
Universitätsklinikum Schleswig-Holstein, Lübeck, 23538, Germany
連絡先, 045150043691
Axel Merseburger, 研究責任者
Klinikum Rechts Der Isar Der Technischen Universität München, Munich, 81675, Germany
連絡先, 498941402522
Margitta Retz, 研究責任者
Universitätsklinikum Münster - Albert Schweitzer Campus, Münster, 48149, Germany
Martin Boegemann, 研究責任者
Klinikum Nürnberg Nord, Nuremberg, 90419, Germany
連絡先, + 49 911 398 3085
Marinela Augustin, 研究責任者
Studienpraxis Urologie, Nürtingen, 72622, Germany
連絡先, 4915201622246
Tilman Todenhöfer, 研究責任者
Universitätsmedizin Rostock, Rostock, 18057, Germany
連絡先, +49 381 494 7801
Angelika Borkowetz, 研究責任者
Universitaetsklinikum Tuebingen, Tübingen, 72076, Germany
Eva Erne, 研究責任者
Universitaetsklinikum Ulm, Ulm, 89081, Germany
連絡先, 4973150058036
Friedemann Zengerling, 研究責任者
Universitaetsklinikum Wuerzburg, Würzburg, 97080, Germany
Anna Seitz, 研究責任者
Semmelweis Egyetem, Budapest, 1082, Hungary
Peter Nyirady, 研究責任者
Országos Onkológiai Intézet, Budapest, 1122, Hungary
連絡先, 3612248600
Lajos Geczi, 研究責任者
Debreceni Egyetem Klinikai Kozpont, Debrecen, 4032, Hungary
連絡先, 3652255840
Peter Arkosy, 研究責任者
Szabolcs Szatmár Bereg Vármegyei Oktatókórház, Nyíregyháza, 4400, Hungary
連絡先, 003642599700 EXT 2334
Ágnes Wéber, 研究責任者
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ, Szeged, 6725, Hungary
Aniko Maraz, 研究責任者
Instituto Tumori Giovanni Paolo II, Bari, 70124, Italy
連絡先, +39 0805555391
Marica Gentile, 研究責任者
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, 20133, Italy
連絡先, 0390223903028
Giuseppe Procopio, 研究責任者
Ospedale San Raffaele, Milan, 20132, Italy
連絡先, +390226435789
Andrea Necchi, 研究責任者
Azienda Ospedaliera Universitaria Federico II, Napoli, 80131, Italy
連絡先, +393404166268
Luigi Formisano, 研究責任者
Istituto Oncologico Veneto IRCCS, Padua, 35128, Italy
連絡先, +390423732137
Marco Maruzzo, 研究責任者
Azienda Ospedaliera Universitaria Pisana, Pisa, 56126, Italy
Luca Galli, 研究責任者
Fondazione Policlinico Universitario Agostino Gemelli, Roma, 00168, Italy
連絡先, 390630154838
Roberto Iacovelli, 研究責任者
Istituto Nazionale Tumori Regina Elena, Rome, 00144, Italy
Fabio Calabro, 研究責任者
Amsterdam UMC, locatie VUmc, Amsterdam, 1081 HV, Netherlands
連絡先, +31(0)20-4444321
Jens Voortman, 研究責任者
Amphia Ziekenhuis, locatie Breda Molengracht, Breda, 4818 CK, Netherlands
連絡先, +31 76 595 5146
Hans Westgeest, 研究責任者
Radboudumc, Nijmegen, 6525 GA, Netherlands
連絡先, +31 (0)24 3610353
Mira Franken, 研究責任者
Erasmus Medisch Centrum, Rotterdam, 3015 GD, Netherlands
連絡先, +31618842777
Debbie Robbrecht, 研究責任者
IN VIVO, Bydgoszcz, 85-048, Poland
連絡先, 48888455614
Anna Krause, 研究責任者
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie, Koszalin, 75-581, Poland
連絡先, 48502204953
Mariusz Kwiatkowski, 研究責任者
Pratia MCM Krakow, Krakow, 30-727, Poland
連絡先, 48 505 169 040
Anna Drosik Kwasniewska, 研究責任者
AIDPORT Sp. z o.o., Skórzewo, 60-185, Poland
Piotr Tomczak, 研究責任者
GYNCENTRUM Szpital, Sosnowiec, 41-208, Poland
Sylwia Szablowska-Siwik, 研究責任者
Luxmed Onkologia sp. z o. o., Warsaw, 01-748, Poland
Pawel Morawski, 研究責任者
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie, Warsaw, 02-781, Poland
連絡先, 48225462433
Pawel Wiechno, 研究責任者
WSD MEDI, Warsaw, 02-786, Poland
Anna Wasko Grabowska, 研究責任者
Medical Concierge Centrum Medyczne, Warsaw, 02-798, Poland
連絡先, 602300992
Piotr Radziszewski, 研究責任者
Szpital Grochowski im. dr med. Rafała Masztaka SPZOZ, Warsaw, 04-073, Poland
連絡先, 48 22 5152 591
Iwona Skoneczna, 研究責任者
Wojskowy Instytut Medyczny Państwowy Instytut Badawczy, Warsaw, 04-141, Poland
Szymon Borowiec, 研究責任者
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu, Wrocaw, 50-556, Poland
Anna Kolodziej, 研究責任者
National Cancer Center, Goyang-si, 10408, South Korea
Ho Kyung Seo, 研究責任者
Chungnam national university hospital, Junggu, 35015, South Korea
Hyo Jin Lee, 研究責任者
Gachon University Gil Medical Center, Namdong-gu, 21565, South Korea
Joo-Hwan Park, 研究責任者
Seoul National University Bundang Hospital, Seongnam, 13620, South Korea
連絡先, 820317877842
Eun Hee Jung, 研究責任者
Seoul National University Hospital, Seoul, 03080, South Korea
Jeonghwan Youk, 研究責任者
Severance Hospital, Yonsei University Health System, Seoul, 03722, South Korea
連絡先, 82222288138
Sang Joon Shin, 研究責任者
Asan Medical Center, Seoul, 05505, South Korea
連絡先, 82-2-3010-3266
Inkeun Park, 研究責任者
Samsung Medical Center, Seoul, 06351, South Korea
連絡先, 82-2-3410-3459
Se Hoon Park, 研究責任者
The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, 06591, South Korea
連絡先, 82-10-9056-6116
In-Ho Kim, 研究責任者
Ewha Womans University Mokdong Hospital, Seoul, 07985, South Korea
Jungmin Jo, 研究責任者
Hospital Infanta Cristina, Badajoz, 06006, Spain
連絡先, 924218040
Marta Gonzalez Cordero, 研究責任者
Institut Català d'Oncologia (ICO) - Badalona, Badalona, 08916, Spain
連絡先, 34 934978925
Albert Font Pous, 研究責任者
OSI Ezkerraldea-Enkarterri-Cruces - Hospital Universitario Cruces, Barakaldo, 48903, Spain
Ricardo Fernández Rodríguez, 研究責任者
Hospital Universitari Vall d'Hebron, Barcelona, 08035, Spain
連絡先, 932746000 x 4350
Rafael Morales Barrera, 研究責任者
Hospital Clínic de Barcelona, Barcelona, 08036, Spain
連絡先, 34 932275402
Oscar Reig Torras, 研究責任者
Hospital de la Santa Creu i Sant Pau, Barcelona, 08041, Spain
連絡先, 34935565638
Jose Pablo Maroto Rey, 研究責任者
Hospital Universitario Reina Sofia, Córdoba, 14004, Spain
MARIA JOSE MENDEZ VIDAL, 研究責任者
Hospital General Universitario de Elche, Elche, 03202, Spain
Federico Jose Vazquez Mazon, 研究責任者
Institut Català d'Oncologia (ICO) - Girona, Girona, 17007, Spain
連絡先, 34972225834
Nuria Sala Gonzalez, 研究責任者
Instituto Catalan de Oncologia - Hospital Duran i Reynals, Hospitalet, 08907, Spain
連絡先, +34 932603261
Irene Ortiz Rubio, 研究責任者
Hospital Insular de Gran Canaria, Las Palmas de Gran Canaria, 35016, Spain
Alfonso Gómez de Liaño Lista, 研究責任者
Hospital La Princesa, Madrid, 28006, Spain
連絡先, +34915202200
Patricia Toquero Diez, 研究責任者
Hospital General Universitario Gregorio Marañon, Madrid, 28009, Spain
連絡先, 34914265238
Jose Arranz Arija, 研究責任者
MD Anderson Cancer Center, Madrid, 28033, Spain
Lucrecia Ruiz, 研究責任者
Hospital Universitario Ramón y Cajal, Madrid, 28034, Spain
連絡先, (+34) 913368263
Pablo Gajate Borau, 研究責任者
Hospital Clinico San Carlos, Madrid, 28040, Spain
連絡先, 913307545
Javier Puente Vazquez, 研究責任者
Hospital Universitario 12 de Octubre, Madrid, 28041, Spain
連絡先, 0034 91 390 83 39
Daniel Castellano Gauna, 研究責任者
Hospital Universitario La Paz, Madrid, 28046, Spain
連絡先, 917277516
Alvaro Pinto Marin, 研究責任者
H.R.U Málaga - Hospital General, Málaga, 29011, Spain
連絡先, 951308130
Alvaro Montesa Pino, 研究責任者
Complejo Hospitalario de Navarra, Pamplona, 31009, Spain
連絡先, 8.00 - 15.00
Nuria Lainez Milagro, 研究責任者
Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón, 28223, Spain
連絡先, +34914521987
ELENA ALMAGRO CASADO, 研究責任者
Hospital Universitari Sant Joan de Reus, Reus, 43204, Spain
Marc Grifoll Escoda, 研究責任者
Hospital Universitario Marqués de Valdecilla, Santander, 39008, Spain
連絡先, 607552230
Ignacio Duran Martinez, 研究責任者
CHUS - Hospital Clinico Universitario, Santiago de Compostela, 15706, Spain
連絡先, 34981950512
Urbano Anido Herranz, 研究責任者
Hospital Universitario Virgen Del Rocio, Seville, 41013, Spain
連絡先, 34955013068
Begona Perez Valderrama, 研究責任者
Hospital Arnau de Vilanova, Valencia, 46015, Spain
連絡先, 679370073
Jose Garcia Sanchez, 研究責任者
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, 807, Taiwan
Wen-Jeng Wu, 研究責任者
Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung Niao Sung Dist, 83301, Taiwan
連絡先, 886-972919696
Yu-Li Su, 研究責任者
China Medical University Hospital, Taichung, 404332, Taiwan
連絡先, +886422052121
Chao-Hsiang Chang, 研究責任者
Taichung Veterans General Hospital, Taichung, 407, Taiwan
Jian-Ri Li, 研究責任者
National Cheng Kung University Hospital, Tainan, 704, Taiwan
連絡先, 0980971870
Wen-Pin Su, 研究責任者
Chi Mei Medical Center, Tainan, 71004, Taiwan
Nai-Wen Kang, 研究責任者
Chi Mei Hospital - Liouying Branch, Tainan, 73657, Taiwan
Yen-Hsun Chen, 研究責任者
National Taiwan University Hospital, Taipei, 10002, Taiwan
Yu-Chieh Tsai, 研究責任者
National Taiwan University Cancer Center (NTUCC), Taipei, 106, Taiwan
Ying-Chun Shen, 研究責任者
Taipei Veterans General Hospital, Taipei, 11217, Taiwan
連絡先, 886228757519-323
Yi-Hsiu Huang, 研究責任者
Chang Gung Medical Foundation-Linkou Branch, Taoyuan District, 333, Taiwan
連絡先, 886-3-3281200
See-Tong Pang, 研究責任者
Adana Medical Park Seyhan Hastanesi, Adana, 01140, Turkey (Türkiye)
連絡先, 905325005269
Ali Besen, 研究責任者
Sakarya University School of Medicine, Adapazarı, 54100, Turkey (Türkiye)
連絡先, +90 5054785576
Ilhan Hacibekiroglu, 研究責任者
Ankara University Health Practice and Research Hospitals, Ankara, 06100, Turkey (Türkiye)
連絡先, 00903125957321
Yuksel Urun, 研究責任者
Ankara Bilkent Şehir Hastanesi, Ankara, 06800, Turkey (Türkiye)
連絡先, 905555306271
Mehmet Ali Nahit Sendur, 研究責任者
Antalya Egitim ve Arastırma Hastanesi, Antalya, 07100, Turkey (Türkiye)
連絡先, 905336488217
Derya KIVRAK SALIM, 研究責任者
Memorial Diyarbakır Hastanesi, Diyarbakır, 21070, Turkey (Türkiye)
連絡先, 90 5337677131
Muhammet kaplan, 研究責任者
Trakya University, Edirne, 22030, Turkey (Türkiye)
連絡先, 90 5334364678
Muhammet Hacioglu, 研究責任者
Gaziantep Universitesi Sahinbey Arastirma ve Uygulama Hastanesi, Gaziantep, 27310, Turkey (Türkiye)
連絡先, 05065118207
tulay kus, 研究責任者
Dr. Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, 34890, Turkey (Türkiye)
Mahmut Gumus, 研究責任者
Marmara Universitesi Pendik Egitim Arastirma Hastanesi, Istanbul, 34899, Turkey (Türkiye)
連絡先, 905433389339
Murat Sari, 研究責任者
zmir Katip Çelebi Üniversitesi Atatürk Eitim Ve Aratrma Hastanesi, Izmir, 35360, Turkey (Türkiye)
連絡先, 905324078648
Ahmet Alacacioglu, 研究責任者
Huddersfield Royal Infirmary, Huddersfield, HD3 3EA, United Kingdom
Ursula Hofmann, 研究責任者
St Bartholomew's Hospital, London, EC1A 7BE, United Kingdom
連絡先, 02078828494
Thomas Powles, 研究責任者
University College London Hospital, London, NW1 2PG, United Kingdom
Ursula McGovern, 研究責任者
Royal Marsden Hospital (Sutton), London, SM2 5PT, United Kingdom
連絡先, +44 (0) 2086613529
Robert Huddart, 研究責任者
Royal Marsden Hospital (Chelsea), London, SW3 6JJ, United Kingdom
連絡先, +44 (0) 2086613529
Robert Huddart, 研究責任者
The Christie NHS Foundation Trust, Manchester, M20 4BX, United Kingdom
連絡先, 01614468409
Yee Pei Song, 研究責任者
Weston Park Hospital, Sheffield, S10 2SJ, United Kingdom
Syed Hussain, 研究責任者