임상 레이더 AI | ||
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임상시험 NCT07424248 (TBI-Pain)은(는) 통증, 만성 통증, Chronic Pain Due to Injury에 대해 대상자모집전 상태입니다. 모든 세부 정보를 보려면 임상시험 레이더 카드 뷰와 AI 발견 도구를 확인하거나 여기에서 무엇이든 물어보세요. | ||
하나의 임상시험이 필터 기준과 일치합니다.
카드 뷰
Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury 100 관찰 연구
임상시험 세부 정보는 주로 영어로 제공됩니다. 하지만 임상 레이더 AI가 도와드릴 수 있습니다! '임상시험 설명'를 클릭하여 선택한 언어로 임상시험 정보를 확인하고, 이에 대해 AI와 논의해 보세요.
임상시험 NCT07424248 (TBI-Pain)은(는) 통증, 만성 통증, Chronic Pain Due to Injury에 대해 알아보는 관찰연구입니다. 현재 상태는 대상자모집전이며, 2026년 2월 15일부터 참여 신청이 가능합니다. 100명의 참여자를 모집할 예정입니다. Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)이(가) 진행하는 이 연구는 2026년 12월 15일까지 진행될 예정입니다. ClinicalTrials.gov의 가장 최근 정보는 2026년 2월 24일에 갱신되었습니다.
간단한 개요
Combat-related traumatic brain injury (cTBI), particularly blast-related injury, is frequently associated with the development of persistent and disabling chronic pain. This prospective observational cohort study aims to determine the incidence, phenotypes, and early predictors of chronic pain following mild to moderate combat-related TBI. Adults will be enrolled within 14 days of injury and followed for 6 months. Th...더 보기
상세한 설명
Combat-related traumatic brain injury (cTBI), particularly blast-associated injury, is a major contributor to the development of chronic pain syndromes in military populations. Pain following cTBI may present as chronic post-traumatic headache, cervicogenic pain, neuropathic pain, or widespread pain associated with central sensitization. The interaction between neuronal injury, psychological stress (including PTSD), ...더 보기
공식 제목
Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury
질환명
통증만성 통증Chronic Pain Due to Injury기타 연구 식별자
- TBI-Pain
- 09v313022026
NCT 번호
실제 연구 시작일
2026-02-15
최신 업데이트 게시
2026-02-24
예상 연구 완료일
2026-12-15
계획된 등록 인원
100
연구종류
관찰연구
상태
대상자모집전
키워드
Combat-related traumatic brain injury
cTBI
Blast injury
Chronic pain
Neuropathic pain
Sleep disturbance
Pain prediction
Military trauma
cTBI
Blast injury
Chronic pain
Neuropathic pain
Sleep disturbance
Pain prediction
Military trauma
시험군 / 개입
| 참가자 그룹/시험군 | 개입/치료 |
|---|---|
Combat-Related TBI Cohort Adults aged 18-60 years with mild to moderate combat-related traumatic brain injury enrolled within 14 days of injury. Participants will undergo standardized clinical, psychological, and pain assessments and will be followed prospectively for 6 months to evaluate the development of chronic pain. | 해당 없음 |
주요결과변수
이차결과변수
| 결과변수 | 측정값 설명 | 시간 범위 |
|---|---|---|
Clinically significant chronic pain at 3 months after injury. | Clinically significant chronic pain is defined as pain intensity ≥4 on the 0-10 Numerical Rating Scale (NRS) and/or pain interference score ≥4 on the Brief Pain Inventory (BPI) at 3 months post-injury. The proportion of participants meeting this definition will be calculated, and predictors of chronic pain will be evaluated using multivariable modeling. | From injury to 3 months (±2 weeks) post-injury. |
| 결과변수 | 측정값 설명 | 시간 범위 |
|---|---|---|
Clinically significant chronic pain at 6 months | Presence of chronic pain defined as NRS ≥4 and/or BPI interference score ≥4 at 6 months post-injury. | 6 months (±3 weeks) after injury |
Neuropathic pain phenotype | Presence of neuropathic pain features defined as DN4 score ≥4. | 3 and 6 months after injury |
참여 도우미
적격성 기준
연령대
성인
최소 연령
18 Years
참여 가능한 성별
전체
- Age 18 to 60 years
- Combat-related traumatic brain injury (blast, impact, or combined mechanism)
- Mild to moderate traumatic brain injury
- Enrollment within 14 days after injury
- Ability to provide written informed consent
- Severe traumatic brain injury with prolonged impaired consciousness
- Pre-existing severe psychiatric disorder unrelated to trauma
- Chronic pain condition predating the traumatic brain injury
- Inability to complete follow-up assessments
- Severe medical condition limiting participation
Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)연구 대표 연락처
연락처: Dmytro Dmytriiev, PhD.Professor, +380674309449, [email protected]
1 1개국에 임상시험 장소
Superhumans War Trauma Center, Lviv, Ukraine