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O estudo clínico NCT07495774 (INSPIRE-PPH) para Hipertensão pulmonar está em recrutamento. Consulte a visualização em cartões do Radar de Estudos Clínicos e as ferramentas de descoberta de IA para ver todos os detalhes. Ou pergunte qualquer coisa aqui. | ||
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Insights Into Pediatric Pulmonary Hypertension: A Real-World Registry of Epidemiology and Outcomes (INSPIRE-PPH) 450 Dados de vida real Pediátrico Adolescente Observacional
Os detalhes do estudo clínico estão disponíveis principalmente em inglês. No entanto, a IA Trial Radar pode ajudar! Basta clicar em 'Explicar o estudo' para visualizar e discutir as informações do estudo no idioma selecionado.
O estudo clínico NCT07495774 (INSPIRE-PPH) é um estudo observacional para Hipertensão pulmonar. Seu status atual é: em recrutamento. O estudo começou em 4 de janeiro de 2006 e pretende incluir 450 participantes. Coordenado por Guangdong Provincial People's Hospital e deve ser concluído em 31 de dezembro de 2035. Essas informações foram atualizadas no ClinicalTrials.gov em 27 de março de 2026.
Resumo
Pediatric pulmonary hypertension (PH) shares similarities with PH in adulthood, but specific differences still require unique approaches. Despite major advances, risk scores for pediatric PH still need to be validated, and targeted drug therapies in pediatric populations remain under-studied. Consequently, there is a great need for comprehensive real-world longitudinal data of pediatric PH.
The INSPIRE-PH registry i...
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Insights Into Epidemiology, Management, and Outcomes of Pediatric Pulmonary Hypertension: The INSPIRE-PH Multicenter Real-World Registry
Condições médicas
Hipertensão pulmonarOutros IDs do estudo
- INSPIRE-PPH
- INSPIRE-PPH-Registry
Número NCT
Data de início (real)
2006-01-04
Última atualização postada
2026-03-27
Data de conclusão (estimada)
2035-12-31
Inscrição (estimada)
450
Tipo de estudo
Observacional
Status
Em recrutamento
Palavras-chave
pediatric
pulmonary hypertension
real-world
epidemiology
outcome
pulmonary hypertension
real-world
epidemiology
outcome
Desfecho primário
Desfecho secundário
| Medida de desfecho | Descrição da medida | Prazo |
|---|---|---|
death | From enrollment to the event, assessed through study completion (target follow-up duration of 10 years; extended follow-up available for earlier enrollees) | |
transplantation | From enrollment to the event, assessed through study completion (target follow-up duration of 10 years; extended follow-up available for earlier enrollees) |
| Medida de desfecho | Descrição da medida | Prazo |
|---|---|---|
PH-related hospitalization | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
atrial septostomy | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
Potts shunt | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) | |
clinical worsening | Clinical worsening is defined as the first occurrence of death, transplantation, hospitalization for PH, atrial septostomy or Potts shunt, with need for escalation of PH-targeted therapy, or worsening functional status. | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) |
decline in WHO functional class | From enrollment to first occurrence of the event, assessed through study completion (continue to be followed after event occurrence until primary outcome or study completion) |
Assistente de participação
Critérios de elegibilidade
Idades elegíveis
Criança, Adulto
Sexos elegíveis
Todos
- Children and adolescents aged <18 years at diagnosis
- Diagnosed pulmonary hypertension (PH) according to the prevailing diagnostic criteria at the time of enrollment
- Enrollment in the registry at participating centers
- Provision of informed consent by patients and/or legal guardians
- Availability for longitudinal follow-up
- Inability to confirm PH diagnosis due to insufficient clinical or hemodynamic data
- Refusal or inability to provide informed consent
Guangdong Provincial People's HospitalResponsável pelo estudo
Zhi-Cheng Jing, MD, Investigador principal, Prof., Guangdong Provincial People's Hospital
Contato central do estudo
Contato: Jie-Xin Zhang, Dr., +86-18629534652, [email protected]
1 Locais do estudo em 1 países
Guangdong
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, 510080, China
Em recrutamento