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临床试验 NCT07496086 针对术后疼痛目前招募中。请查看临床试验雷达卡片视图和 AI 发现工具了解所有详情，或在此提出任何问题。
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External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative Pain in Laparoscopic Radical Gastrectomy 100 随机化 创新疗法

招募中
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临床试验NCT07496086是一项针对术后疼痛的干预性研究试验，目前试验状态为招募中。试验始于2026年3月20日，计划招募100名患者。该研究由General Hospital of Ningxia Medical University主导，预计于2026年11月3日完成。试验数据来源于ClinicalTrials.gov，最后更新时间为2026年3月27日。
简要概括
Postoperative pain is highly prevalent following laparoscopic radical gastrectomy. Although Transversus abdominis plane block combined with rectus sheath block(TAP+RSB） can effectively alleviate this pain, it still has many limitations. The external oblique intercostal plane block (EOIB) is a novel nerve block technique that may provide well postoperative analgesia for upper abdominal surgery. Therefore, this study e...显示更多
详细描述
Laparoscopic radical gastrectomy (including subtotal and total gastrectomy) is the most commonly used surgical approach for gastric cancer. Although this technique is less invasive than traditional open surgery, more than 50% of patients still experience moderate to severe acute pain in the early postoperative period, making effective postoperative pain management essential. Regional nerve blockade techniques have be...显示更多
官方标题

Effects of Ultrasound-guided External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative Pain in Laparoscopic Radical Gastrectomy

疾病
术后疼痛
其他研究标识符
  • Lingzi-2026-2
NCT编号
NCT07496086
实际开始日期
2026-03-20
最近更新发布
2026-03-27
预计完成日期
2026-11-03
计划入组人数
100
研究类型
干预性研究
试验分期 (阶段)
不适用
试验状态
招募中
主要目的
治疗方法
分配方式
随机
干预模型
平行
盲法
双盲
试验组/干预措施
参与者组/试验组干预措施/治疗方法
实验性EOIB
After patients entering the operating room, an intravenous line was established, and External Oblique Intercostal Plane Block was performed under ultrasound guidance.
EOIB
With the patient in the supine position, a high-frequency linear array probe (6-15 MHz) is used to perform a sagittal parasagittal oblique scan at the level of the 6th rib, between the right anterior axillary line and midclavicular line. The external oblique muscle, intercostal muscles, and ribs are identified. Using an in-plane technique, a 21G, 100mm block needle is inserted from a superomedial to inferolateral dir...显示更多
实验性TAP+RSB
After patients entering the operating room, an intravenous line was established, and Transversus abdominis plane block combined with rectus sheath block was performed under ultrasound guidance.
TAP+RSB
With the patient in the supine position, above the umbilicus, a linear ultrasound transducer was positioned transversely on the rectus abdominis muscle, and 15 mL of ropivacaine 0.375% was injected into both sides of the aspect between the rectus abdominis muscle and the posterior rectus sheath with a 22G 70-mm block needle using the in-plane technique. At the midaxillary line, a linear ultrasound transducer was posi...显示更多
主要终点
结果指标度量标准描述时间框架
Cumulative opioid consumption within 24 hours postoperatively
Cumulative opioid consumption within 24 hours postoperatively. Conversion to morphine equivalent dose (mg)
24 hours after surgery
次要终点
结果指标度量标准描述时间框架
Pain Intensity
Pain at rest and during coughing will be assessed using the Numerical Rating Scale (NRS, 0-10) at 2, 6, 12, 24, 48, and 72 hours postoperatively.0 represents no pain, and 10 represents the most pain.
2, 6, 12, 24, 48, and 72 hours postoperatively
Quality of Recovery
The 15-item Quality of Recovery scale (QoR-15) was used for assessment at 24, 48, and 72 hours postoperatively. The higher the score, the better the recovery quality
24,48,72 hours after surgery
sleep quality
Sleep quality was assessed using the Richards-Campbell Sleep Questionnaire (RCSQ) on postoperative nights.0 points represent very poor sleep, while 100 points represent very good sleep
24,48,72 hours after surgery
参与助手
资格标准

适龄参与研究
成人, 老年人
最低年龄要求
18 Years
适龄性别
全部
  • Patients aged over 18 years
  • Classified as ASA I-III
  • Scheduled for elective laparoscopic radical gastrectomy under general anesthesia
  • Voluntarily participated and provided written informed consent.

  • Chronic opioid dependence or prior use of analgesic medications for >3 months;
  • Inability to communicate due to severe dementia, language barriers, or terminal illness;
  • History of central and/or peripheral nervous system disorders;
  • Severe renal insufficiency (serum creatinine >442 μmol/L or requiring renal replacement therapy) or severe hepatic insufficiency (Child-Pugh class C);
  • Allergy to local anesthetics.
  • Expected to be transferred to ICU after surgery.
  • Refuse patient control agenesia after surgery.
General Hospital of Ningxia Medical University logoGeneral Hospital of Ningxia Medical University
研究中心联系人
联系人: lingzi Yin, Doctoral, 86-951-674-3252, [email protected]
1 位于 1 个国家/地区的研究中心
General hospital of Ningxia medical university, Yinchuan, China
lingzi Yin, Doctoral, 联系人, 86-951-674-3252, [email protected]
招募中