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De klinische studie NCT07161648 voor Fat Metabolism is rekruterend. Bekijk de kaartweergave van de Klinische Studies Radar en de AI-ontdekkingstools voor alle details. Of stel hier een vraag.
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Kaartweergave

Use of Neuromuscular Electrical Stimulation to Prevent Exercise Resistance 30 Lichaamsbeweging

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De klinische studie NCT07161648 is een interventioneel studie bij Fat Metabolism met de status rekruterend. Het doel is om 30 deelnemers te includeren vanaf 17 oktober 2024. De studie wordt geleid door Colorado State University en de voltooiing is gepland op 30 september 2026. Laatste update op ClinicalTrials.gov: 14 november 2025.
Beknopte samenvatting
The study will find out if 100 minutes of electrical stimulation of muscle prevents the unfavorable consequence of insufficient exercise.
Uitgebreide beschrijving
Exercise resistance is characterized by the absence of exercise induced improvements in fat metabolism following a meal, and results from prolonged sedentary behavior between successive workouts (i.e. 2+ sedentary days between exercise bouts). The suggested energy expenditure threshold for avoiding exercise resistance is the equivalent of walking ~8,500 steps/day. However, population data indicate that the typical a...Toon meer
Officiële titel

Use of Neuromuscular Electrical Stimulation to Prevent Exercise Resistance

Aandoeningen
Fat Metabolism
Andere studie-ID's
  • 5208
NCT-ID
Startdatum (Werkelijk)
2024-10-17
Laatste update geplaatst
2025-11-14
Verwachte einddatum
2026-09-30
Inschrijving (Geschat)
30
Studietype
Interventioneel
FASE
N.v.t.
Status
Rekruterend
Trefwoorden
exercise
exercise resistance
electrical stimulation
Primaire doel
Preventie
Toewijzing
Gerandomiseerd
Interventiemodel
Cross-over
Blindering
Geen (Open-label)
Armen / Interventies
Deelnemersgroep/StudiearmInterventie/Behandeling
Geen interventieEstablishing the normal benefit of exercise
Study participants will complete treadmill exercise. During the same day, they will walk a minimum of 8,500 steps. The next day, fat oxidation will be measured after eating a high-fat meal.
N.v.t.
Geen interventieDemonstrating exercise resistance
Study participants will complete treadmill exercise. They will walk no more than 5,000 steps on the same day. The next day, fat oxidation will be measured after eating a high-fat meal.
N.v.t.
ExperimenteelTrying to prevent exercise resistance
Study participants will complete treadmill exercise. They will walk no more than 5,000 steps on the same day. They will receive 100 minutes of neuromuscular electrical stimulation. The next day, fat oxidation will be measured after eating a high-fat meal.
Neuromusculaire elektrische stimulatie
The study participants will engage in 100-minutes of neuromuscular electrical stimulation (NMES). NMES pads are sticky pieces of plastic, similar in size to a 25-cent coin. The pads will be placed on the bellies of thigh muscles (the vastus lateralis, vastus medialis), and calf muscles (the long and short head of the gastrocnemius). These skeletal muscles are selected due to their size (thereby promoting a bigger inc...Toon meer
Primaire uitkomst
UitkomstmaatBeschrijving van de uitkomstmaatTijdsbestek
Fat oxidation
Circulating triglyceride concentration after eating a high fat meal.
Blood will be sampled and triglyceride concentration measured. Study participants will eat a meal. Blood will be sampled and triglyceride concentration measured every 30-minutes for 4 hours.
Deelname-assistent
Geschiktheidscriteria

Leeftijd van deelnemers
Volwassene
Minimumleeftijd
18 Years
Geslachten die in aanmerking komen voor de studie
Allen
Accepteert gezonde vrijwilligers
Ja
  • Regularly active (more than 30 minutes of exercise per day, 3 days per week, over the previous 12 months)
  • Ability to complete at least one hour of treadmill exercise (i.e. jogging/running),
  • Willing to abstain from caffeine and alcohol for 24-hours prior to three different study visits
  • Competency in English

  • Current or previous injuries that may hinder a participant's ability to exercise on a treadmill
  • A history of cardiopulmonary disorder that may be contra-indicative to treadmill exercise
  • Current use of cardio-pulmonary medication to treat a cardio-pulmonary condition
  • Currently breastfeeding
  • Pregnancy
Colorado State University logoColorado State University
Verantwoordelijke instantie
Christopher Bell, Hoofdonderzoeker, Associate Prof, Colorado State University
Centraal Contactpersoon
Contact: Christopher Bell, PhD, 970-491-7522, [email protected]
Contact: Ally Tripure, B.S., 9704913495, [email protected]
1 Studielocaties in 1 landen

Colorado

Colorado State University, Fort Collins, Colorado, 80523, United States
Christopher Bell, Contact, 9704917522, [email protected]
Ally Tripure, Contact, 9704913495, [email protected]
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