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Clinical Trial NCT06380114 for Hpv is recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
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Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination 16,000 Vaccine Study Randomized Adolescent

Recruiting
Clinical Trial NCT06380114 is an interventional study for Hpv that is recruiting. It started on November 4, 2024 with plans to enroll 16,000 participants. Led by University of Rochester, it is expected to complete by November 1, 2027. The latest data from ClinicalTrials.gov was last updated on October 24, 2025.
Brief Summary
Each year in the U.S., ≥20,000 women and 14,000 men are affected by HPV-related cancers, including cervical and oropharyngeal cancer. However, in 2020, only 59% of U.S. adolescents aged 13-17 were up-to-date for HPV vaccination, and rates for 11-12 year olds, the primary target age group for HPV vaccination (when the immune reaction is better and before exposure to HPV infection), are even lower. Standing orders (wri...Show More
Official Title

Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination

Conditions
Hpv
Other Study IDs
NCT ID Number
NCT06380114
Start Date (Actual)
2024-11-04
Last Update Posted
2025-10-24
Completion Date (Estimated)
2027-11
Enrollment (Estimated)
16,000
Study Type
Interventional
PHASE
N/A
Status
Recruiting
Primary Purpose
Health Services Research
Design Allocation
Randomized
Interventional Model
Parallel
Masking
None (Open Label)
Arms / Interventions
Participant Group/ArmIntervention/Treatment
Active ComparatorCommunication Training
Practice personnel (providers and nurses) receive training in communication about HPV vaccination.
Communication
Practice personnel (providers and nurses) receive training in communication about HPV vaccination via an online learning module.
ExperimentalCommunication Training + Standing Orders Training/Implementation
Practice personnel (providers and nurses) receive training in communication about HPV vaccination and training in the implementation of standing orders for HPV vaccination.
Communication
Practice personnel (providers and nurses) receive training in communication about HPV vaccination via an online learning module.
Standing Orders
Practice personnel (providers and nurses) receive training in the implementation of standing orders for HPV vaccination via an online learning module and meetings with the study team.
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Patient-Level Captured Opportunities for HPV Vaccination
The percentage of HPV vaccine eligible patients, aged 9-17, with a practice visit during the specified timeframe of interest who receive \>=1 HPV vaccination.
12-month baseline compared to 12-month intervention compared to 12-month maintenance (control arm vs intervention arm)
Participation Assistant
Eligibility Criteria

Eligible Ages
Child
Minimum Age
9 Years
Eligible Sexes
All
Accepts Healthy Volunteers
Yes
  • active patient in AHP practice

  • patient belonging to a practice with >80% UTD baseline HPV vaccination rate for ages 13-17
  • patient belonging to a practice with <20 11-12 year-olds eligible for an HPV dose
University of Rochester logoUniversity of Rochester195 active studies to explore
Study Responsible Party
Cynthia Rand, Principal Investigator, Professor, Pediatrics, University of Rochester
Study Central Contact
Contact: Robin Bender, (585) 274-1499, [email protected]
1 Study Locations in 1 Countries

New York

University of Rochester Medical Center (URMC), Rochester, New York, 14642, United States
Robin Bender, LMSW, Contact
Recruiting