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Clinical Trial NCT07263932 for PENG Block, Hip Arthroplasty, Total, QoR-15, Numeric Rating Scale is recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here.
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PENG vs PHPB for Hip Arthroplasty Analgesia 132

Recruiting
Clinical Trial NCT07263932 is an observational study for PENG Block, Hip Arthroplasty, Total, QoR-15, Numeric Rating Scale that is recruiting. It started on December 1, 2025 with plans to enroll 132 participants. Led by Ankara City Hospital Bilkent, it is expected to complete by July 1, 2026. The latest data from ClinicalTrials.gov was last updated on December 12, 2025.
Brief Summary
Total hip arthroplasty (THA) is a commonly performed surgical procedure, and its incidence continues to rise with the aging population. Effective postoperative analgesia facilitates early mobilization and accelerates recovery. The pericapsular nerve group (PENG) block provides analgesia to the anterior hip capsule by targeting the articular branches of the femoral, obturator, and accessory obturator nerves. However, ...Show More
Detailed Description
Total hip arthroplasty (THA) is a widely performed surgical procedure, and its incidence continues to increase with the aging population. It is an effective intervention to improve the quality of life in patients with advanced osteoarthritis or rheumatoid arthritis. Postoperative pain is one of the most common complications following THA. Effective postoperative analgesia facilitates early mobilization and accelerate...Show More
Official Title

Postoperative Analgesic Effectiveness of Pericapsular Nerve Block (PENG) and Posterior Hip Pericapsular Block (PHPB) in Hip Arthroplasty

Conditions
PENG BlockHip Arthroplasty, TotalQoR-15Numeric Rating Scale
Publications
Scientific articles and research papers published about this clinical trial:
Other Study IDs
  • E2-25-12993
NCT ID Number
NCT07263932
Start Date (Actual)
2025-12-01
Last Update Posted
2025-12-12
Completion Date (Estimated)
2026-07-01
Enrollment (Estimated)
132
Study Type
Observational
Status
Recruiting
Arms / Interventions
Participant Group/ArmIntervention/Treatment
PENG Group
The group that will receive the preoperative Pericapsular Nerve Group (PENG) block
PENG Block
Patients in this group will also undergo elective total hip arthroplasty (THA) under spinal anesthesia.A preoperative Pericapsular Nerve Group (PENG) block will be performed under ultrasound guidance using 20 mL of 0.25% bupivacaine. The injection will be administered between the psoas tendon and the iliac bone to block the articular branches of the femoral, obturator, and accessory obturator nerves, providing analge...Show More
PENG + PHPB Group
The group that will receive the preoperative Pericapsular Nerve Group (PENG) block and Posterior Hip Pericapsular Block (PHPB)
PENG Block and Posterior Hip Pericapsular Block
Patients in this group will also undergo elective total hip arthroplasty (THA) under spinal anesthesia.A preoperative Pericapsular Nerve Group (PENG) block will be performed under ultrasound guidance using 20 mL of 0.25% bupivacaine. The injection will be administered between the psoas tendon and the iliac bone to block the articular branches of the femoral, obturator, and accessory obturator nerves, providing analge...Show More
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Postoperative pain
Postoperative pain will be assessed using the Numeric Rating Scale (NRS; 0 = no pain, 10 = worst imaginable pain) at rest and during movement at 0, 2, 6, 8, 12, 24, 36, and 48 hours after surgery. The NRS scores will be compared between the two study groups (PENG vs. PENG + PHPB) to evaluate the effectiveness of the blocks in postoperative analgesia following total hip arthroplasty.
Up to 48 hours postoperatively
Secondary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
QUALİTY OF RECOVERY-15
The quality of postoperative recovery will be assessed using the validated 15-item Quality of Recovery questionnaire (QoR-15). The total score ranges from 0 (very poor recovery) to 150 (excellent recovery). The score will be measured preoperatively and at 24 and 48 hours postoperatively to compare recovery quality between the two groups.
Preoperative, 24, and 48 hours postoperatively
MANUEL MUSCLE TEST
Quadriceps muscle strength will be evaluated using the Manual Muscle Test (MMT) scale at 6, 12, and 24 hours after surgery. The MMT scale ranges from 0 (no contraction) to 5 (normal strength). A score \<3 indicates quadriceps weakness.
6, 12, and 24 hours postoperatively
Rescue analgesic
The time from the end of surgery to the patient's first request for rescue analgesia will be recorded. Rescue analgesia consists of intravenous tramadol 100 mg administered if the Numeric Rating Scale (NRS) score is ≥ 4. This measure will compare the analgesic duration provided by the two blocks (PENG vs. PENG + PHPB).
0-48 hours postoperatively
Postoperative Nausea and Vomiting (PONV)
The presence of postoperative nausea and/or vomiting will be recorded during the first 48 hours following surgery.
0-48 hours postoperatively
Length of Hospital Stay
The duration of hospitalization will be measured from the day of surgery to discharge.
Up to discharge (approximately 3-5 days postoperatively)
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
  • Patients scheduled for elective total hip arthroplasty (THA) under spinal anesthesia
  • ASA physical status I-II
  • Age ≥18 years
  • Body Mass Index (BMI) between 18-35 kg/m²
  • Patients who provide written informed consent

  • Age <18 years
  • ASA physical status ≥III
  • Known allergy or contraindication to study medications (local anesthetics, opioids, etc.)
  • Severe cardiac, renal, hepatic, or pulmonary failure
  • Revision total hip arthroplasty
  • Coagulopathy or anticoagulant use
  • Local infection or neuropathic findings at the injection site
  • Chronic inflammatory diseases or chronic corticosteroid use
  • Diagnosed neuropsychiatric disorders
  • Pregnancy or lactation
  • Inability or unwillingness to read, understand, or sign the informed consent form
  • Obesity (BMI >35 kg/m²)
  • Failed spinal anesthesia or conversion to general anesthesia
  • Active malignancy or patients receiving radiotherapy/chemotherapy
  • Active systemic infection or ongoing antibiotic therapy (except prophylaxis)
  • Contraindication to regional anesthesia techniques
  • Chronic opioid or analgesic use for pain disorders
  • History of intracranial mass, increased intracranial pressure, epilepsy, cerebrovascular accident, neuromuscular disease, or motor/sensory deficits
Ankara City Hospital Bilkent logoAnkara City Hospital Bilkent
Study Central Contact
Contact: Tuba kölge altınok, Resident, +905387671646, [email protected]
1 Study Locations in 1 Countries

Çankaya

Ankara Bilkent City Hospital Departmant of Anesthesiology and Reanimation, Ankara,Çankaya, Ankara, Çankaya, 06800, Turkey (Türkiye)
Recruiting