בטא
רדאר קליני AI
הניסוי הקליני NCT04649242 עבור Pediatric Migraine הוא מגייס. לכל הפרטים, עיינו בתצוגת הכרטיסים של רדאר ניסויים קליניים ובכלי הגילוי של AI. אפשר גם לשאול כל דבר כאן.
מחקר אחד תואם לקריטריוני המסנן
תצוגת כרטיסים

Randomized Study in Children and Adolescents With Migraine: Acute Treatment שלב III 2,100 אקראי מתבגרים

מגייס
פרטי הניסויים הקליניים זמינים בעיקר באנגלית. רדאר קליני AI יכול לעזור! לחץ על 'הסבר את המחקר' כדי לצפות ולשוחח על מידע מהמחקר בשפה המועדפת עליך.
ניסוי קליני NCT04649242 מתקיים כדי לבדוק את טיפול עבור Pediatric Migraine. זהו מחקר שלב III מסוג התערבותי שנמצא כעת במצב מגייס. המחקר התחיל ב-15 בינואר 2021 ומתוכנן לכלול 2,100 משתתפים. המחקר מנוהל על ידי פייזר וצפוי להסתיים ב-9 בינואר 2029. מידע זה עודכן לאחרונה באתר ClinicalTrials.gov ב-20 במרץ 2026.
סיכום קצר
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
כותרת רשמית

Phase 3, Multicenter, Randomized, Double-blind, Group Sequential, Placebo-controlled Study to Assess Efficacy and Safety of Rimegepant for the Treatment of Migraine (With or Without Aura) in Children and Adolescents ≥ 6 to < 18 Years of Age

מצבים רפואיים
Pediatric Migraine
מזהי מחקר נוספים
  • BHV3000-311
  • C4951002 (מזהה אחר) (Alias Study Number)
  • 2020-003517-35 (מזהה רישום) (CTIS (EU))
  • 2024-512743-23-00 (מזהה רישום) (CTIS (EU))
מספר NCT
תחילת המחקר (בפועל)
2021-01-15
עדכון אחרון שפורסם
2026-03-20
סיום המחקר (מוערך)
2029-01-09
משתתפים (מתוכנן)
2,100
סוג המחקר
התערבותי
שלב
שלב III
סטטוס
מגייס
מילות מפתח
Migraine
Acute treatment
Phonophobia
Photophobia
Nausea
Pediatric
Children
Adolescent
Pediatric Migraine
מטרה ראשית
טיפול
הקצאת טיפול
אקראי
דגם מתערב
שיוך רצף
עיוורון
משולש
זרועות / התערבויות
קבוצת משתתפים/זרועהתערבות/טיפול
משווה פעילBHV3000 (active drug)
BHV3000 (rimegepant) 75 mg or 50 mg ODT
Rimegepant/BHV3000
BHV3000 (rimegepant) 75 mg or 50 mg ODT
פלצבו להשוואהPlacebo
Matching 75 mg or 50 mg ODT placebo
פלצבו תואם
Matching 75 mg or 50 mg ODT placebo
מדדי תוצאה ראשיים
מדד תוצאהתיאור המדידהטווח זמן
To evaluate the efficacy of rimegepant compared with placebo in the acute treatment of migraine in adolescent population (≥ 12 to <18 years of age) as measured by pain freedom using the number of patients reporting no pain.
Pain freedom will be assessed in adolescent population (≥ 12 to \< 18 years of age) on a 4-point numeric rating scale (0=none, 1=mild, 2=moderate, 3=severe).
2 hours post-dose
מדדי תוצאה משניים
מדד תוצאהתיאור המדידהטווח זמן
To compare rimegepant with placebo for pain freedom in children and adolescents combined.
Pain freedom will be assessed in children and adolescents (≥ 6 to \< 18 years of age) using a 4-point numeric rating scale (0=none, 1=mild, 2=moderate, 3=severe). Pain freedom will be assessed in children (\> 6 to \< 12 years of age) using the 5-Face VAS (Face 5 = 'severe pain', Faces 4 and 3 = 'moderate pain', Face 2 = 'mild pain', Face 1 = 'no pain').
2 hours post-dose
To compare rimegepant with placebo on freedom from the most bothersome symptom (MBS) associated with migraine in adolescents.
Freedom from MBS (nausea, phonophobia or photophobia) will be measured using a binary scale (0=absent, 1=present).
2 hours post-dose
To compare rimegepant with placebo on the probabilities of requiring rescue medication within in adolescents.
Use of rescue medication will be assessed using the numbers of participants that take rescue medication.
Within 24 hours and 48 hours of initial treatment
To compare rimegepant with placebo on sustained pain freedom in adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 24 hours post-dose
To compare rimegepant with placebo on sustained pain freedom in adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 48 hours post-dose
To compare rimegepant with placebo on the ability to function normally as reported on the Functional Disability scale in adolescents.
The proportion of participants able to function normally will be assessed using the number that self-report as "normal" on the Functional Disability scale.
2 hours post-dose
To compare rimegepant with placebo for pain freedom in children.
Pain freedom will be assessed using the number of children (≥ 6 to \< 12 years of age) that report no pain measured by a 5-Face VAS (Face 5 = 'severe pain', Faces 4 and 3 = 'moderate pain', Face 2 = 'mild pain', Face 1 = 'no pain').
2 hours post-dose
To compare rimegepant with placebo on freedom from the most bothersome symptom (MBS) associated with migraine in children and combined children and adolescents.
Freedom from the most bothersome symptom (nausea, phonophobia or photophobia) will be assessed using the number of participants that report the absence of MBS measured using a binary scale (0=absent, 1=present).
2 hours post-dose
To compare rimegepant with placebo on the probabilities of requiring rescue medication in children and combined children and adolescents.
The probabilities of requiring rescue medication will be assessed using the numbers of participants that take rescue medication within initial treatment.
Within 24 hours and 48 hours of initial treatment.
To compare rimegepant with placebo on sustained pain freedom in children and combined children and adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 24 hours post-dose
To compare rimegepant with placebo on sustained pain freedom in children and combined children and adolescents.
Sustained pain freedom will be assessed using the number of participants that do not use any rescue medications and do not experience any headache pain post dose.
2 to 48 hours post-dose
To compare rimegepant with placebo on freedom from photophobia in adolescents, children and combined children and adolescents.
Freedom from photophobia will be assessed by the number of participants that report the absence of photophobia post dose that reported the presence of photophobia at baseline.
2 hours post-dose
To compare rimegepant with placebo on freedom from phonophobia in adolescents, children and combined children and adolescents.
Freedom from phonophobia will be assessed by the number of participants that report the absence of phonophobia post dose that reported the presence of phonophobia at baseline.
2 hours post-dose
To compare rimegepant with placebo on freedom from nausea in adolescents, children and combined children and adolescents.
Freedom from nausea will be assessed by the number of participants that report the absence of nausea post dose that reported the presence of nausea at baseline.
2 hours post-dose
To compare rimegepant with placebo on pain relief in adolescents, children and combined children and adolescents.
Pain relief will be assessed using the number of participants that report a pain level of moderate or severe at baseline and then report a pain level of none or mild post dose.
2 hours post-dose
To compare rimegepant with placebo in adolescents, children and combined children and adolescents on pain relief.
Time to first report of pain relief will be based on the first time point a participant reports a pain level of none or mild.
Time to patients first report of pain relief of none or mild post dose up to 48 hours.
עוזר השתתפות
קריטריוני זכאות

גילאים מוערכים למחקר
ילד
גיל מינימלי למחקר
6 Years
מגדרים מוערכים למחקר
הכל
  1. History of migraine (with or without aura) for > 6 months before Screening according to the IHS Classification ICHD-319 specifications for pediatric migraine. History may be verified using both medical records and recall by the participant and/or participant's parent(s)/legal representative(s).

  2. History of 1 to 8 moderate or severe attacks per month during the 2 months prior to enrollment, with attacks lasting > 3 hours without treatment, and attacks occurring at intervals > 24 hours.

  3. Prophylactic migraine medication are permitted if the dose has been stable for at least 12 weeks prior to the Baseline Visit, and the dose is not expected to change during the course of the study.

    1. Participants may remain on one (1) medication with possible migraine prophylactic effects, excluding CGRP antagonists \[biologic or small molecule\], during the treatment phases.
    2. Concomitant use of a CGRP antagonist, such as erenumab or fremanezumab, is prohibited.
    3. Previously discontinued prophylactic migraine medication must have done so at least 90 days prior to the Screening Visit.
  4. Verbally distinguish between migraine and other types of headaches.

  5. Participants must have a weight > 40 kg at the Screening Visit.

  6. Adequate venous access for blood sampling.

  7. Male and female participants ≥ 6 to < 18 years of age (participants must not reach their 18th birthday during the study).

  1. History of cluster headache or hemiplegic migraine headache.
  2. Confounding and clinically significant pain syndrome that may interfere with the participant's ability to participate in this study.
  3. Current psychiatric condition that is uncontrolled and/or untreated for a minimum of 6 months prior to the Screening Visit. Participants with a lifetime history of psychosis and/or mania.
  4. History of suicidal behavior or major psychiatric disorder.
  5. Current diagnosis or history of substance abuse; positive drug test at Screening.
  6. History of moderate or severe head trauma or other neurological disorder (including seizure disorder) or systemic medical disease that is likely to affect central nervous system functioning.
  7. Recent or planned surgery, requiring general anesthesia, <8 weeks prior to the Screening Visit.
  8. Participant has had gastrointestinal surgery that interferes with physiological absorption and motility (i.e., gastric bypass, duodenectomy, or gastric banding).
  9. Current diagnosis of viral hepatitis or a history of liver disease.
  10. Conditions considered clinically relevant in the context of the study such as uncontrolled hypertension (high blood pressure), diabetes, a life-threatening allergy
איש קשר מרכזי למחקר
איש קשר: Pfizer Pfizer CT.gov Call Center, 1-800-718-1021, [email protected]
245 מיקומי המחקר ב-9 מדינות

Alabama

Achieve Clinical Research, LLC d/b/a Accel Research Sites-Neurology and Neurodiagnostic of Alabama, Birmingham, Alabama, 35244, United States
פעיל, לא מגייס

Arizona

Perseverance Research Center, LLC, Scottsdale, Arizona, 85253, United States
מגייס
Physicians Research Group, Tempe, Arizona, 85284, United States
פעיל, לא מגייס

California

Advanced Research Center, Inc., Anaheim, California, 92805, United States
מגייס
Adult & Child Neurology Medical Associates, Costa Mesa, California, 92627, United States
מגייס
ProScience Research Group, Culver City, California, 90230, United States
מגייס
Memorial Health Services, Fountain Valley, California, 92708, United States
מגייס
Neuro-Pain Medical Center, Fresno, California, 93710, United States
מגייס
Regents of the University of California (UC San Diego), La Jolla, California, 92093, United States
מגייס
Adult & Child Neurology Medical Associates, Long Beach, California, 90806, United States
מגייס
Miller Children's & Women's Hospital Long Beach, Long Beach, California, 90806, United States
מגייס
National Research Institute, Los Angeles, California, 90057, United States
פעיל, לא מגייס
Velocity Clinical Research - North Hollywood, North Hollywood, California, 91606, United States
פעיל, לא מגייס
Children's Hospital of Orange County - Inpatient Pharmacy, Orange, California, 92868, United States
טרם החל גיוס
Children's Hospital of Orange County - Neuroscience Center, Orange, California, 92868, United States
טרם החל גיוס
Children's Hospital of Orange County, Orange, California, 92868, United States
טרם החל גיוס
The Neurology Group, Pomona, California, 91767, United States
מגייס
University of California, Davis Midtown Clinic, Sacramento, California, 95816, United States
פעיל, לא מגייס
UC Davis Medical Center, Investigational Drug Service (IDS) Pharmacy, Sacramento, California, 95817, United States
פעיל, לא מגייס
University of California, Davis Clinical and Translational Science Center Clinical Research (CCRC), Sacramento, California, 95817, United States
פעיל, לא מגייס
Velocity Clinical Research, San Bernardino (IP Delivery and Administering Location), San Bernardino, California, 92408, United States
מגייס
Pacific Clinical Research Management Group LLC, Upland, California, 91786, United States
פעיל, לא מגייס
Sunwise Clinical Research, Walnut Creek, California, 94596, United States
מגייס

Colorado

Children's Hospital Colorado- lnvestigational Drug Services, Aurora, Colorado, 80045, United States
מגייס
Children's Hospital Colorado, Aurora, Colorado, 80045, United States
מגייס
Colorado Springs Neurological Associates, PC, Colorado Springs, Colorado, 80907, United States
מגייס
Colorado Springs Neurological Associates, PC, Colorado Springs, Colorado, 80919, United States
מגייס

Connecticut

CT Clinical Research, Cromwell, Connecticut, 06416, United States
מגייס
Connecticut Children's Medical Center, Hartford, Connecticut, 06106, United States
פעיל, לא מגייס
Ki Health Partners, LLc, dba New England Institute for Clinical Research, Stamford, Connecticut, 06905, United States
מגייס

Delaware

Nemours Children's Hospital, Delaware, Wilmington, Delaware, 19803, United States
פעיל, לא מגייס

District of Columbia

Children's National Medical Center, Washington D.C., District of Columbia, 20010, United States
מגייס

Florida

Topaz Clinical Research, Inc., Apopka, Florida, 32703, United States
פעיל, לא מגייס
Beautiful Minds Clinical Research Center, Cutler Bay, Florida, 33157, United States
הופסק
DeLand Clinical Research Unit, DeLand, Florida, 32720, United States
הופסק
Sarkis Clinical Trials, Gainesville, Florida, 32607, United States
פעיל, לא מגייס
Multi-Specialty Research Associates, Inc., Lake City, Florida, 32055, United States
פעיל, לא מגייס
Watson Clinic Center for Research, Inc., Lakeland, Florida, 33805, United States
הופסק
Watson Clinic LLP, Lakeland, Florida, 33805, United States
הופסק
AppleMed Research Group, LLC, Miami, Florida, 33126, United States
מגייס
Medical Research Center of Miami II, Inc, Miami, Florida, 33134, United States
פעיל, לא מגייס
Nicklaus Children's Hospital, Research Institute, Miami, Florida, 33155, United States
טרם החל גיוס
South Florida Research Phase I-IV, Inc, Miami, Florida, 33166, United States
מגייס
Brainstorm Research, Miami, Florida, 33176, United States
פעיל, לא מגייס
Advanced Research for Health Improvement, LLC/ Dr. Cordero's Pediatric Office, Naples, Florida, 34102, United States
פעיל, לא מגייס
Aqualane Clinical Research, Naples, Florida, 34105, United States
מגייס
Coastal Clinical Research Specialists, Orange Park, Florida, 32073, United States
פעיל, לא מגייס
Clinical Associates of Orlando, LLC, Orlando, Florida, 32819, United States
מגייס
Bioresearch Institute, Pembroke Pines, Florida, 33026, United States
הופסק
Forcare Clinical Research, Tampa, Florida, 33613, United States
מגייס
Premiere Research Institute at Palm Beach Neurology, West Palm Beach, Florida, 33407, United States
פעיל, לא מגייס

Georgia

Children's Healthcare of Atlanta, Inc., Atlanta, Georgia, 30329, United States
מגייס
Childrens Healthcare of Atlanta, Atlanta, Georgia, 30329, United States
מגייס
Rare Disease Research, LLC, Atlanta, Georgia, 30329, United States
פעיל, לא מגייס
Pivotal Clinical Research & Associates, LLC, Brunswick, Georgia, 31520, United States
מגייס
CenExel iResearch, LLC, Decatur, Georgia, 30030, United States
מגייס

Illinois

Chicago Headache Center & Research Institute, Chicago, Illinois, 60657, United States
מגייס
AMR-Baber Research Inc, Naperville, Illinois, 60563, United States
מגייס

Indiana

Options Research Group, LLC, Westfield, Indiana, 46074, United States
מגייס

Iowa

Velocity Clinical Research, Sioux City, Sioux City, Iowa, 51106, United States
מגייס
Integrated Clinical Trial Services, West Des Moines, Iowa, 50265, United States
מגייס

Kansas

Clinical Associates Midwest, LLC, Kansas City, Kansas, 66214, United States
מגייס
College Park Family Care Center Physicians Group- Neurology Research Dept., Overland Park, Kansas, 66212, United States
פעיל, לא מגייס

Kentucky

Kentucky Neuroscience Institute Child Neurology-- "Patients Seen", Lexington, Kentucky, 40504, United States
פעיל, לא מגייס
UK Center for Clinical and Translational Science (CCTS) -- "Patients Seen", Lexington, Kentucky, 40536, United States
פעיל, לא מגייס
University of Kentucky Hospital, Lexington, Kentucky, 40536, United States
פעיל, לא מגייס

Louisiana

Ochsner Clinic Foundation, New Orleans, Louisiana, 70121, United States
פעיל, לא מגייס
Neurology and Headache Center, Inc., Shreveport, Louisiana, 71105, United States
פעיל, לא מגייס

Massachusetts

Boston Clinical Trials, Boston, Massachusetts, 02131, United States
פעיל, לא מגייס
MedVadis Research Corporation, Waltham, Massachusetts, 02451, United States
פעיל, לא מגייס

Michigan

Michigan Head Pain & Neurological Institute, Ann Arbor, Michigan, 48104, United States
מגייס
Corewell Health, for and on behalf of Spectrum Health Hospital and Corewell Health Medical Group, Grand Rapids, Michigan, 49503, United States
מגייס
Corewell Health, Helen DeVos Children's Hospital, Grand Rapids, Michigan, 49503, United States
מגייס
Wellnow Urgent Care and Research, Kalamazoo, Michigan, 49048, United States
פעיל, לא מגייס
Beaumont Hospital Royal Oak Campus, Royal Oak, Michigan, 48073, United States
מגייס

Minnesota

Brackenridge Outpatient Research Pharmacy, Rochester, Minnesota, 55905, United States
מגייס
Clinical Research Trials Unit, Rochester, Minnesota, 55905, United States
מגייס
Mayo Clinic, Rochester, Minnesota, 55905, United States
מגייס

Mississippi

Precise Research Centers, Flowood, Mississippi, 39232, United States
מגייס

Missouri

Sharlin Health Neuroscience Research Center, Ozark, Missouri, 65721, United States
מגייס
Clinvest Research, LLC, Springfield, Missouri, 65810, United States
פעיל, לא מגייס

Montana

Boeson Research, Great Falls, Montana, 59405, United States
מגייס
Boeson Research, Kalispell, Montana, 59901, United States
פעיל, לא מגייס
Heart & Hands Midwifery, Kalispell, Montana, 59901, United States
פעיל, לא מגייס
Blue Moose Pediatrics, Missoula, Montana, 59804, United States
מגייס
Boeson Research Laboratory, Missoula, Montana, 59804, United States
מגייס
Boeson Research, Missoula, Montana, 59804, United States
מגייס

Nebraska

Alivation Research, LLC., Lincoln, Nebraska, 68526, United States
הופסק
Children's Hospital & Medical Center, Omaha, Nebraska, 68114, United States
מגייס

New Jersey

HMH Jersey Shore University Medical Center, Neptune City, New Jersey, 07753, United States
מגייס

New York

Dent Neurosciences Research Center, Amherst, New York, 14226, United States
מגייס
True North Neurology, Commack, New York, 11725, United States
מגייס
Northwell Health/ Division of Pediatric Neurology, Lake Success, New York, 11042, United States
מגייס
NYU Langone Hospital-Long Island, Clinical Research Center, Mineola, New York, 11501, United States
פעיל, לא מגייס
NYU Langone Hospital-Long Island, Pediatric Neurology, Mineola, New York, 11501, United States
פעיל, לא מגייס
New York Neurology Associates, New York, New York, 10003, United States
מגייס
Weill Cornell Medicine, New York, New York, 10021, United States
מגייס
Mount Sinai Hospital - Pharmacy Department, New York, New York, 10029, United States
פעיל, לא מגייס
Columbia University Medical Center Research Pharmacy, New York, New York, 10032, United States
פעיל, לא מגייס
Columbia University Pediatric Neuromuscular Center, New York, New York, 10032, United States
פעיל, לא מגייס
Irving Center for Clinical and Translational Research, Outpatient Clinical Research Unit, New York, New York, 10032, United States
פעיל, לא מגייס
The Neurological Institute of New York, New York, New York, 10032, United States
פעיל, לא מגייס
The Trustees of Columbia University and The New York and Presbyterian Hospital, New York, New York, 10032, United States
פעיל, לא מגייס
North Suffolk Neurology P.C, Port Jefferson Station, New York, 11776, United States
פעיל, לא מגייס
Finger Lakes Clinical Research, Rochester, New York, 14618, United States
הופסק
Prime Global Research, LLC, The Bronx, New York, 10456, United States
הופסק

North Carolina

New Hope Clinical Research, Charlotte, North Carolina, 28211, United States
פעיל, לא מגייס
OnSite Clinical Solutions, LLC, Charlotte, North Carolina, 28277, United States
מגייס
Velocity Clinical Research, Inc., Durham, North Carolina, 27701, United States
מגייס
Headache Wellness Center, PC, Greensboro, North Carolina, 27405, United States
מגייס

Ohio

Akron Children's Hospital, Akron, Ohio, 44308, United States
מגייס
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229, United States
מגייס
Velocity Clinical Research, Cincinnati, Ohio, 45242, United States
מגייס
University Hospitals Cleveland Medical Center, Cleveland, Ohio, 44106, United States
מגייס
Nationwide Children's Hospital, Columbus, Ohio, 43205, United States
פעיל, לא מגייס
Wellnow Urgent Care and Research, Columbus, Ohio, 43228, United States
פעיל, לא מגייס
Neuro-Behavioral Clinical Research, Inc., North Canton, Ohio, 44720, United States
פעיל, לא מגייס

Oklahoma

IPS Research Company, Oklahoma City, Oklahoma, 73106, United States
פעיל, לא מגייס
Lynn Institute of Tulsa, Tulsa, Oklahoma, 74135, United States
פעיל, לא מגייס

Oregon

Velocity Clinical Research, Grants Pass, Grants Pass, Oregon, 97527, United States
פעיל, לא מגייס
Providence Health & Services Investigational Drug Services Westside, Portland, Oregon, 97225, United States
מגייס
Providence Neuroscience Institute - Research Coordinator's Office, Portland, Oregon, 97225, United States
מגייס
Providence Pediatric Neurology, Portland, Oregon, 97225, United States
מגייס
Providence St. Vincent Medical Center, Portland, Oregon, 97225, United States
מגייס

Pennsylvania

Clario, Philadelphia, Pennsylvania, 19103, United States
מגייס
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United States
פעיל, לא מגייס

Rhode Island

Velocity Clinical Research-Providence, East Greenwich, Rhode Island, 02818, United States
מגייס

South Carolina

Premier Neurology, PC, Greenville, South Carolina, 29605, United States
פעיל, לא מגייס
Tribe Clinical Research, LLC, Greenville, South Carolina, 29607, United States
פעיל, לא מגייס
Velocity Clinical Research - Greenville, Greenville, South Carolina, 29615, United States
פעיל, לא מגייס

Tennessee

Holston Medical Group., Kingsport, Tennessee, 37660, United States
פעיל, לא מגייס
Holston Medical Group, Kingsport, Tennessee, 37660, United States
פעיל, לא מגייס
Le Bonheur Children's Hospital - Outpatient Building, Memphis, Tennessee, 38103, United States
מגייס
Le Bonheur Children's Hospital, Memphis, Tennessee, 38103, United States
מגייס
Le Bonheur Childrens Hospital - Childrens Foundation Research Institute, Memphis, Tennessee, 38103, United States
מגייס
Access Clinical Trials, Inc., Nashville, Tennessee, 37203, United States
פעיל, לא מגייס

Texas

Dell Children's Medical Center, Austin, Texas, 78723, United States
מגייס
Child Neurology Consultants of Austin - South Austin, Austin, Texas, 78749, United States
מגייס
Child Neurology Consultants of Austin - Central Austin, Austin, Texas, 78757, United States
מגייס
BioBehavioral Research of Austin, Austin, Texas, 78759, United States
פעיל, לא מגייס
Houston Clinical Trials, LLC, Bellaire, Texas, 77401, United States
מגייס
Infinite Research Group, LLC, Dallas, Texas, 75201, United States
מגייס
Children's Medical Center, Dallas, Dallas, Texas, 75235, United States
מגייס
Children's Medical Center, Pediatric Anesthesiology Research (Study supplies only), Dallas, Texas, 75235, United States
מגייס
Cedar Health Research, Dallas, Texas, 75251, United States
מגייס
FutureSearch Trials of Dallas, LLC, Dallas, Texas, 75251, United States
מגייס
The University of Texas Southwestern Medical Center, Dallas, Texas, 75390, United States
מגייס
ANESC Research, El Paso, Texas, 79912, United States
מגייס
North Texas Institute of Neurology and Headache, Frisco, Texas, 75034, United States
פעיל, לא מגייס
UTHealth Houston, Houston, Texas, 77030, United States
מגייס
Pain and Headache Centers of Texas, Houston, Texas, 77054, United States
מגייס
SCLA Management, Houston, Texas, 77077, United States
מגייס
Houston Clinical Research,LLC., Houston, Texas, 77081, United States
פעיל, לא מגייס
NeuroCare Plus, Houston, Texas, 77094, United States
מגייס
AIM Trials, LLC, Plano, Texas, 75093, United States
מגייס

Utah

JBR Clinical Research, Salt Lake City, Utah, 84107, United States
מגייס
Wasatch Clinical Research , LLC(Administrative Location), Salt Lake City, Utah, 84107, United States
מגייס

Vermont

The University of Vermont Medical Center, Burlington, Vermont, 05401, United States
פעיל, לא מגייס

Virginia

Pediatric Research of Charlottesville, LLC (Regulatory Only), Charlottesville, Virginia, 22902, United States
מגייס
Pediatric Research of Charlottesville, LLC, Charlottesville, Virginia, 22902, United States
מגייס
Children's Hospital of the King's Daughters, Norfolk, Virginia, 23507, United States
מגייס
Children's Specialty Group, PLLC, Norfolk, Virginia, 23507, United States
מגייס
Children's Specialty Group, PLLC, Division of Childhood & Adolescent Neurology, Norfolk, Virginia, 23510, United States
מגייס
National Clinical Research, Inc., Richmond, Virginia, 23294, United States
פעיל, לא מגייס

Washington

Northwest Clinical Research Center, Bellevue, Washington, 98007, United States
מגייס
Eastside Therapeutic Resource, Inc. dba Core Clinical Research, Everett, Washington, 98201, United States
פעיל, לא מגייס
Seattle Children's Hospital Investigational Drug Services, Seattle, Washington, 98105, United States
מגייס
Seattle Children's Hospital, Seattle, Washington, 98105, United States
מגייס

Wisconsin

Clinical Investigation Specialists, Inc, Kenosha, Wisconsin, 53144, United States
מגייס
University Hospital, Madison, Wisconsin, 53792, United States
מגייס

British Columbia

OCT Research ULC, Kelowna, British Columbia, V1Y 1Z9, Canada
מגייס

Quebec

Diex Recherche Sherbrooke Inc, Sherbrooke, Quebec, J1L 0H8, Canada
פעיל, לא מגייס

Anhui

First Affiliated Hospital of Bengbu Medical College Neurology, Bengbu, Anhui, 233000, China
מגייס
Anhui Provincial Hospital, Hefei, Anhui, 230000, China
מגייס

Beijing Municipality

Chinese PLA General Hospital, Beijing, Beijing Municipality, 100089, China
מגייס

Chongqing Municipality

" The First Affiliated Hospital of Chongqing Medical University", Chongqing, Chongqing Municipality, 400042, China
מגייס

Gansu

Lanzhou university second hospital, Lanzhou, Gansu, 730030, China
מגייס

Guangdong

Shenzhen Children's Hospital, Shenzhen, Guangdong, 518034, China
מגייס

Hainan

Hainan General Hospital, Haikou, Hainan, 571140, China
מגייס

Hebei

The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, China
מגייס
The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050004, China
מגייס

Henan

People's Hospital of Zhengzhou, Zhengzhou, Henan, 450000, China
מגייס

Hubei

Jingzhou First People's Hospital, Jingzhou, Hubei, 434000, China
מגייס
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China
מגייס
Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
מגייס

Hunan

The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410000, China
מגייס
Hunan Children's Hospital, Changsha, Hunan, 410007, China
מגייס
The Third Xiangya Hospital of Central South University, Changsha, Hunan, 410013, China
מגייס

Jiangsu

The Second People's Hospital of Lianyungang, Lianyungang, Jiangsu, 222002, China
מגייס
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China
מגייס
Wuxi Children's Hospital, Wuxi, Jiangsu, 214023, China
מגייס
Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214115, China
מגייס
Xuzhou Children's Hospital, Xuzhou, Jiangsu, 221002, China
מגייס
Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, China
מגייס

Jilin

The First Hospital of Jilin University, Pediatric Neurology, Changchun, Jilin, 130021, China
מגייס

Ningxia

General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 756000, China
מגייס

Shaanxi

Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China
מגייס
Xi'an Gaoxin Hospital Neurology Department, Xi'an, Shaanxi, 710075, China
מגייס
Yan 'an University Xianyang Hospital, Xianyang, Shaanxi, 716000, China
מגייס

Shandong

Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, 250013, China
מגייס
Liaocheng People's Hospital, Liaocheng, Shandong, 252000, China
מגייס

Sichuan

West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, China
מגייס

Zhejiang

Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310052, China
מגייס
Ningbo Women and Children's Hospital, Ningbo, Zhejiang, 315012, China
מגייס
The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China
מגייס
Lu 'an People's Hospital, Lu'an, China
מגייס
Children's Hospital of Shanghai, Shanghai, China
מגייס
Shengjing Hospital of China Medical University, Shenyang, China
מגייס
The First Affiliated Hospital of Shihezi University School of Medicine, Shihezi, China
פעיל, לא מגייס
Wuhan Children's Hospital, Wuhan, China
מגייס

Fukuoka

Jinnouchi Neurosurgical Clinic, Kasuga-shi, Fukuoka, 816-0802, Japan
מגייס
Ikeda Neurosurgical Clinic, Kasuga-shi, Fukuoka, 816-0824, Japan
מגייס

Gunma

Hikita Pediatric Clinic, Kiryu-shi, Gunma, 3760035, Japan
מגייס

Hyōgo

Konan Medical Center, Higashinada-ku Kobe-shi, Hyōgo, 658-0064, Japan
מגייס
Yamaguchi Clinic, Nishinomiya-shi, Hyōgo, 663-8204, Japan
מגייס

Ibaraki

Mito Kyodo General Hospital, Mito, Ibaraki, 310-0015, Japan
מגייס

Kagoshima-ken

Tanaka Neurosurgery & Headache Clinic, Kagoshima, Kagoshima-ken, 890-0052, Japan
מגייס

Miyagi

Sendai Headache and Neurology Clinic, Taihaku-ku Sendai-shi, Miyagi, 982-0014, Japan
מגייס

Osaka

Tennoji Dai Brain Clinic, Abeno-ku Osaka-shi, Osaka, 545-0053, Japan
מגייס
Tominaga Clinic, Naniwa-ku, Osaka, 556-0015, Japan
מגייס

Tokyo

Tokyo Headache Clinic, Shibuya-ku, Tokyo, 151-0051, Japan
מגייס
Tokyo Medical University Hospital, Shinjuku-ku, Tokyo, 160-0023, Japan
טרם החל גיוס
Local lndependent Administrative Corporation Hiroshima City Hospital Organization Hiroshima City, Hiroshima, 730-8518, Japan
מגייס

Mexico City

Clinstile S.A. de C.V., Col. Roma Norte, Mexico City, C.P. 06700., Mexico
מגייס

Sinaloa

Neurociencias Estudios Clinicos S.C., Culiacán, Sinaloa, 800200, Mexico
מגייס

State of Mexico

Clinical Reseach Institute, S.C., Tlalnepantla, State of Mexico, C.P. 54055, Mexico
מגייס
Unidad de Investigacion en Salud de Chihuahua S.C., Chihuahua City, 31203, Mexico
מגייס

Lower Silesian Voivodeship

MIGRE Polskie Centrum Leczenia Migreny Anna Gryglas-Dworak, Wroclaw, Lower Silesian Voivodeship, 52-210, Poland
מגייס
NZOZ Wielospecjalistyczna Poradnia Lekarska SYNAPSIS, Lech Szczechowski, Katowice, 40-123, Poland
פעיל, לא מגייס
Centrum Medyczne Plejady, Krakow, 30-363, Poland
מגייס
Wojewódzki Specjalistyczny Szpital Dzieciecy im. Sw. Ludwika w Krakowie, Apteka Szpitalna, Krakow, 31-503, Poland
מגייס
Clinical Research Center Sp. z.o.o. Medic-R Spolka komandytowa, Poznan, 61-731, Poland
מגייס
Euromedis Sp. z o. o., Szczecin, 70-111, Poland
פעיל, לא מגייס

Cantabria

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, 39008, Spain
פעיל, לא מגייס
Hospital Universitario Vall d'Hebron, Barcelona, 08035, Spain
מגייס
Centre d'Atencio Primaria Balenya, Barcelona, 08550, Spain
פעיל, לא מגייס
Instituto de Investigaciones del Sueno, Madrid, 28036, Spain
פעיל, לא מגייס
Hospital Universitario Virgen del Rocío, Seville, 41013, Spain
מגייס
Hospital Clinico Universitario de Valladolid, Valladolid, 47005, Spain
מגייס

Skåne LÄN [se-12]

ProbarE i Lund AB, Lund, Skåne LÄN [se-12], 22222, Sweden
מגייס
Avdelningen för kliniska Prövningar, Universitetssjukhuset Örebro, Örebro, 703 62, Sweden
פעיל, לא מגייס
ProbarE i Stockholm AB, Stockholm, 113 29, Sweden
מגייס
Leicester Royal Infirmary, Leicester, LE1 5WW, United Kingdom
פעיל, לא מגייס
Re:Cognition Health Limited, London, W1G 9JF, United Kingdom
מגייס
Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, United Kingdom
מגייס