ट्रायल रडार AI | ||
|---|---|---|
क्लिनिकल ट्रायल NCT03954574 (PEX-NET) के लिए Pulmonary Circulation Diseases वर्तमान में भर्ती जारी है। सभी विवरणों के लिए क्लिनिकल ट्रायल रडार कार्ड दृश्य और AI खोज उपकरण देखें, या यहाँ कुछ भी पूछें। | ||
एक परीक्षण फ़िल्टर मानदंडों से मेल खाता है
कार्ड दृश्य
खोज पर वापस जाएँ
ग्रेज़ चिकित्सा विश्वविद्यालयPulmonary Hemodynamics During Exercise - Research Network (PEX-NET)
चिकित्सा परीक्षण का विवरण मुख्य रूप से अंग्रेजी में उपलब्ध है। हालाँकि, ट्रायल रडार AI मदद कर सकता है! बस 'परीक्षण समझाएं' पर क्लिक करें और अपनी चुनी हुई भाषा में परीक्षण की जानकारी देखें और चर्चा करें।
क्लिनिकल परीक्षण NCT03954574 (PEX-NET) एक प्रेक्षणीय चिकित्सकीय अध्ययन है जो Pulmonary Circulation Diseases से जुड़ा हुआ है। परीक्षण वर्तमान में भर्ती जारी चल रहा है। इसकी शुरुआत 1 दिसंबर 2018 को हुई थी, और इसमें कुल 1,500 प्रतिभागियों के नामांकन की योजना है। ग्रेज़ चिकित्सा विश्वविद्यालय इस परीक्षण का नेतृत्व कर रहे हैं और इसके 31 दिसंबर 2029 तक पूरा होने की उम्मीद है। ClinicalTrials.gov वेबसाइट पर यह जानकारी 27 अप्रैल 2025 को अंतिम बार अपडेट की गई थी।
संक्षिप्त सारांश
The purpose of this Clinical Research Collaboration is to investigate the prognostic implications of pulmonary hemodynamics during exercise based on a large scale multi-centre approach by using retrospective and prospective analysis of hemodynamic data.
आधिकारिक शीर्षक
Pulmonary Hemodynamics During Exercise - Research Network
चिकित्सीय स्थितियाँ
Pulmonary Circulation Diseasesअन्य अध्ययन आईडी
- PEX-NET
- 30-437 ex 17/18
NCT नंबर
अध्ययन प्रारंभ तिथि (वास्तविक)
2018-12-01
अंतिम अद्यतन प्रकाशित
2025-04-27
अध्ययन की समाप्ति तिथि (अनुमानित)
2029-12-31
नामांकन (अनुमानित)
1,500
अध्ययन प्रकार
प्रेक्षणीय
स्थिति
भर्ती जारी
समूह/हस्तक्षेप
| प्रतिभागी समूह/हाथ | हस्तक्षेप/इलाज |
|---|---|
Retrospective patient cohort | Assessment of Pulmonary Hemodynamics During Exercise by Right Heart Catheterization all patients undergo right heart catheterization during exercise due to clinical reasons. Results of this and other Routine clinical tests will be included in the registry |
Prospective patient cohort | Assessment of Pulmonary Hemodynamics During Exercise by Right Heart Catheterization all patients undergo right heart catheterization during exercise due to clinical reasons. Results of this and other Routine clinical tests will be included in the registry |
प्राथमिक परिणाम माप
द्वितीयक परिणाम माप
| परिणाम माप | माप विवरण | समय सीमा |
|---|---|---|
Number of Participants who die during observation | The investigators aim to assess the prognostic relevance of pulmonary hemodynamics during exercise as assessed by right heart catheterization by using a multi-centre approach and to identify independent predictors of adverse events. Separate data sets will be analysed for the retrospective and prospective Evaluation. | 6 years |
Number of Participants undergoing lung Transplantation during observation | Occurrences of lung transplantations | 6 years |
| परिणाम माप | माप विवरण | समय सीमा |
|---|---|---|
Number of Participants being hospitalized during observation | Number of hospitalizations | 6 years |
Number of Participants who develop pulmonary Hypertension as assessed by right heart catheterization | Diagnosis of pulmonary hypertension | 6 years |
Number of Participants with newly initiated pulmonary arterial Hypertension medication during observation | Evaluation of medication initiations | 6 years |
पात्रता मानदंड
अध्ययन के लिए पात्र आयु
वयस्क, वृद्ध वयस्क
अध्ययन के लिए न्यूनतम आयु
18 Years
अध्ययन के लिए पात्र लिंग
सभी
- Patients (females and males; age: above 18yrs) with intermediate or high echocardiographic probability of PH and/or unexplained dyspnea, and/or associated conditions for PAH as clinical indication for RHC at rest and exercise
- Written informed consent of participating subjects after being fully briefed (for prospective analysis)
- Patients with incomplete hemodynamic data at rest or exercise
- Patients without sufficient follow-up data (information on survival / lung transplantation)
- advanced tumour disease or other diseases with a short life expectancy, except pulmonary vascular diseases
- advanced heart failure with pulmonary arterial wedge pressure (PAWP) > 18 mmHg at rest
- uncontrolled systemic arterial hypertension (RR values > 160/100 mmHg at rest)
- FEV1<50% predicted
- TLC<60% predicted
ग्रेज़ चिकित्सा विश्वविद्यालय120 सक्रिय क्लिनिकल ट्रायल्स खोजे जाने के लिएEuropean Respiratory Societyअध्ययन केंद्रीय संपर्क
संपर्क: Gabor Kovacs, MD, +43-316-385, [email protected]
32 14 देशों में अध्ययन स्थल
Arizona
University of Arizona, Banner University Medical Center, Phoenix, Arizona, 85724, United States
Rajeev Saggar, संपर्क, [email protected]
भर्ती जारी
California
University of California, Los Angeles, Lung & Heart-Lung Transplant and Pulmonary Hypertension Programs, David Geffen School of Medicine, Los Angeles, California, 90095, United States
Rajan Saggar, संपर्क, [email protected]
भर्ती जारी
Maryland
Johns Hopkins Hospital, Advanced HF, MCS, Transplant Cardiology, Baltimore, Maryland, USA, Baltimore, Maryland, 21287, United States
Steven Hsu, संपर्क, [email protected]
भर्ती जारी
Massachusetts
Massachusetts General Hospital, Cardiology Division and Pulmonary Unit, Boston, Massachusetts, 02114, United States
Gregory Lewis, संपर्क, [email protected]
Bradley A. Maron, संपर्क, [email protected]
भर्ती जारी
Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, 02138, United States
David Systrom, संपर्क, [email protected]
भर्ती जारी
Minnesota
University of Minnesota Medical School, Division of Cardiology, Department of Medicine, Lillehei Heart Institute Minneapolis, Minnesota, USA, Minneapolis, Minnesota, 55455, United States
Thenappan Thenappan, संपर्क, [email protected]
भर्ती जारी
Mayo Clinic, Division of Cardiovascular Diseases, Department of Medicine, Rochester, Minnesota, 85259, United States
Barry Borlaug, संपर्क, [email protected]
भर्ती जारी
South Carolina
Medical University of South Carolina, Charleston, South Carolina, 29425, United States
Ryan Tedford, संपर्क, [email protected]
भर्ती जारी
Royal Prince Alfred Hospital, Respiratory Medicine, Camperdown, Australia
Edmund Lau, संपर्क, [email protected]
भर्ती जारी
Medical University of Graz, Graz, Austria
Gabor Kovacs, MD, संपर्क, +43-316-385, [email protected]
भर्ती जारी
Free University of Brussels, Faculty of Medicine, Physiology, Brussels, Belgium
Robert Naeije, संपर्क, [email protected]
भर्ती जारी
University of São Paulo Medical School, São Paulo, Brazil
Rogerio Souza, संपर्क, [email protected]
भर्ती जारी
Department of Cardiology, Aarhus University Hospital, Denmark, Aarhus, Denmark
Mads Andersen, संपर्क, [email protected]
भर्ती जारी
Centre Chirurgical Marie Lannelongue, Thoracic and Vascular Surgery, Paris, France
Philippe Herve, संपर्क, [email protected]
भर्ती जारी
Centre de Référence de l'Hypertension Pulmonaire, Université ParisSud - Université Paris-Saclay, Hôpital Bicêtre, Assistance Publique Hôpitaux de Paris, Paris, France
Marc Humbert, संपर्क, [email protected]
भर्ती जारी
Sorbonne Universités, Neurophysiologie respiratoire expérimentale et clinique, Paris, France
Pierantonio Laveneziana, संपर्क, [email protected]
भर्ती जारी
University of Cologne, Klinik III fuer Innere Medizin, Cologne, Germany
Stephan Rosenkranz, संपर्क, [email protected]
भर्ती जारी
Justus-Liebig-University Giessen, Department of Internal Medicine, Giessen, Germany
Henning Gall, संपर्क, [email protected]
भर्ती जारी
Thorax Clinic Heidelberg, Centre for Pulmonary Hypertension, Heidelberg, Germany
Ekkehard Grünig, संपर्क, [email protected]
भर्ती जारी
Academic Teaching Hospital of the Julius Maximilian University of Würzburg, Würzburg, Germany
Matthias Held, संपर्क, [email protected]
भर्ती जारी
University of Rome La Sapienza, Cardiovascular and Respiratory Sciences, Roma, Italy
Dario Vizza, संपर्क, [email protected]
भर्ती जारी
VU Medisch Centrum, Pulmonology, Amsterdam, Netherlands
Anton vonk Noordegraaf, संपर्क, [email protected]
भर्ती जारी
Otwock Medical Center of Postgraduate Education, Department of Pulmonary Circulation and Thromboembolic Diseases, Otwock, Poland
Adam Torbicki, संपर्क, [email protected]
भर्ती जारी
Barcelona Hospital Clínic, Pneumologia, Barcelona, Spain
Joan Albert Barbera, संपर्क, [email protected]
भर्ती जारी
University Hospital of Zurich, Internal Medicine, Zurich, Switzerland
Silvia Ulrich, संपर्क, [email protected]
भर्ती जारी
Scottish Pulmonary Vascular Unit, Glasgow, United Kingdom
Martin Johnson, संपर्क, [email protected]
भर्ती जारी
Imperial College, NHS Healthcare NHS Trust, National Pulmonary Hypertension Service, London, United Kingdom
Luke Howard, संपर्क, [email protected]
भर्ती जारी
Royal Hallamshire Hospital, Sheffield Pulmonary Vascular Disease Unit, Sheffield, United Kingdom
Robin Condliffe, संपर्क, [email protected]
भर्ती जारी