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O estudo clínico NCT07203430 para Low Back Pain, Chronic está ainda não recrutando. Consulte a visualização em cartões do Radar de Estudos Clínicos e as ferramentas de descoberta de IA para ver todos os detalhes. Ou pergunte qualquer coisa aqui.
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Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise

Ainda não recrutando
Os detalhes do estudo clínico estão disponíveis principalmente em inglês. No entanto, a IA Trial Radar pode ajudar! Basta clicar em 'Explicar o estudo' para visualizar e discutir as informações do estudo no idioma selecionado.
O estudo clínico NCT07203430 é um ensaio intervencionista para Low Back Pain, Chronic. Seu status atual é: ainda não recrutando. O recrutamento está programado para iniciar em 20 de outubro de 2025, com o objetivo de incluir 22 participantes. Coordenado por a Universidade da Flórida Central e deve ser concluído em 20 de outubro de 2026. Essas informações foram atualizadas no ClinicalTrials.gov em 2 de outubro de 2025.
Resumo
The purpose of this study is to evaluate the longitudinal effects of a four-week dynamic resistance training program using the 45-degree Roman chair on pain sensitivity changes after exercise and lumbar muscle performance in individuals with chronic low back pain (LBP). This study will consist of three specific aims. Aim 1 examines changes in local exercise-induced hypoalgesia. Aim 2 will assess changes in lumbar multifidus and erector spinae thickness using ultrasound imaging before and after the intervention. Aim 3 will evaluate changes in lumbar extensor strength (handheld dynamometry (HHD)) and endurance (Biering-Sørensen test).
Título oficial

Assessing Adaptations in Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise Intervention in Individuals With Low Back Pain

Condições
Low Back Pain, Chronic
Outros IDs do estudo
  • 12
Número NCT
NCT07203430
Data de início (real)
2025-10-20
Última atualização postada
2025-10-02
Data de conclusão (estimada)
2026-10-20
Inscrição (estimada)
22
Tipo de estudo
Intervencionista
FASE
N/A
Status
Ainda não recrutando
Palavras-chave
Exercise
Low Back Pain
Propósito principal
Tratamento
Alocação do design
Randomizado
Modelo de intervenção
Atribuição paralela
Cegamento (Mascaramento)
Nenhum (Estudo aberto)
Braços / Intervenções
Grupo de participantes/BraçoIntervenção/Tratamento
ExperimentalIntervention Group
During visits 2-13, participants will attend 2-3 sessions per week, with a minimum of 48 hours between visits, and must complete all study visits 6 weeks after enrollment. Participants in the intervention group will perform 3 sets of low back extension exercise on the Roman chair until volitional exhaustion. The three sets will be performed to volitional exhaustion or 20 repetitions, whichever comes first. If more than 20 repetitions can be completed after a set the investigator will add resistance according to the NSCA's guidelines (2.5-10% increase).
45-Degree Roman Chair Exercise
Participants in the intervention group will perform 3 sets of low back extension exercise on the Roman chair until volitional exhaustion. The three sets will be performed to volitional exhaustion or 20 repetitions, whichever comes first. If more than 20 repetitions can be completed after a set the investigator will add resistance according to the NSCA's guidelines (2.5-10% increase).
Nenhuma intervençãoControl Group
Participants in the control group will not complete the low back extension exercise and will be told to continue activity as usual. All participants will complete a training log and detail the type of resistance exercise performed, the number of sets and repetitions completed, and the weight used.
N/A
Desfecho primário
Medida de desfechoDescrição da medidaPrazo
Exercise Induced Hypoalgesia
Participants will perform one set of back extension exercise on a 45-degree Roman chair until volitional exhaustion. Pressure Pain Threshold applied over the low back will be examined before and after exercise.
Weeks 1 and 4
Muscle Thickness
Ultrasound imaging to assess muscle thickness of the erector spinae and the multifidus muscles will be completed.
Weeks 1 and 4
Muscle Strength
Back extensor strength will be assessed using maximal voluntary isometric contraction of the back extensor muscles using a handheld dynamometer.
Weeks 1 and 4
Muscle Endurance
The Biering-Sorensen test will be performed in which participants lie prone on a treatment table with the lower body secured to the table. Participants will be instructed to cross their arms over their chest and maintain their torso in a horizontal position with the upper body unsupported, parallel to the floor.
Weeks 1 and 4
Critérios de elegibilidade

Idades elegíveis
Adulto
Idade mínima
18 Years
Sexos elegíveis
Todos
  • chronic low back pain lasting ≥ 12 weeks
  • current pain intensity ≥ 3/10 but no higher than an 8/10 on the Numeric Pain Rating Scale (NPRS) within the past 48 hours
  • resistance trained (defined as 2x/week for the past 8-12 weeks)
  • able to read and speak English for informed consent and completion of questionnaires
  • willing and physically able to complete all testing and intervention sessions.

  • History of spinal surgery, fusion, or fracture within the past 6 months
  • diagnosed degenerative disc disease, scoliosis, or spinal pathology that precludes safe exercise participation
  • use of an assistive device for walking (cane, walker) within the past year
  • pregnancy, due to contraindications for exercise testing and ultrasound -body weight ≥ 300 lbs., which exceeds the safe capacity of the Roman chair --
  • current tobacco/nicotine use
  • current enrollment in physical therapy or structured rehabilitation for LBP,
  • cardiovascular, pulmonary, metabolic, or systemic disease that increases risk during exercise
  • nociplastic pain conditions (e.g., fibromyalgia) or neurological conditions that confound EIH responses
  • inability to complete ≥ 8 Roman chair repetitions with proper form during screening
  • non-English speaking
University of Central Florida logoUniversidade da Flórida Central48 estudos clínicos ativos para explorar
Responsável pelo estudo
Abigail Wilson, Investigador principal, Assistant Professor, University of Central Florida
Contato central do estudo
Contato: Abigail T. Anderson, PT, DPT, PhD, 407-823-1026, [email protected]
1 Locais do estudo em 1 países

Florida

University of Central Florida, Orlando, Florida, 32816, United States
Abigail Anderson, PT, DPT, PhD, Contato, 407-823-1026, [email protected]
Contato, [email protected]
Abigail Anderson, PT, DPT, PhD, Subinvestigador