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Clinical Trial NCT05531565 (AMETHYST) for Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus is recruiting. See the Trial Radar Card View and AI discovery tools for all the details. Or ask anything here. | ||
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BiogenA 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus (AMETHYST) Phase 2, Phase 3 450 Randomized Double-Blind
Clinical Trial NCT05531565 (AMETHYST) is designed to study Treatment for Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus. It is a Phase 2 Phase 3 interventional study that is recruiting, having started on September 13, 2022, with plans to enroll 450 participants. Led by Biogen, it is expected to complete by December 14, 2027. The latest data from ClinicalTrials.gov was last updated on April 2, 2026.
Brief Summary
In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with cutaneous lupus erythematosus (CLE). The study will focus on participants who have either active subacute CLE or chronic CLE, or both. They may also have systemic lupus erythematosus (SLE). The participants did not respond to antimalarial therapy or had problems with the treatment that made it hard to conti...Show More
Detailed Description
Litifilimab is a humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting blood dendritic cell antigen 2. It is an inhibitory receptor expressed on the surface of human plasmacytoid dendritic cell (pDCs) and is being investigated for the potential treatment of systemic lupus erythematosus and cutaneous lupus erythematosus. The primary objectives of the study are to evaluate the efficacy of litifilimab compare...Show More
Official Title
A 2-Part Seamless Part A (Phase 2)/Part B (Phase 3) Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of BIIB059 in Participants With Active Subacute Cutaneous Lupus Erythematosus and/or Chronic Cutaneous Lupus Erythematosus With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST)
Conditions
Subacute Cutaneous Lupus ErythematosusChronic Cutaneous Lupus ErythematosusOther Study IDs
- AMETHYST
- 230LE301
- 2020-000727-40 (EudraCT Number)
- EU CT Number (Other Identifier) (2023-505634-94)
NCT ID Number
Start Date (Actual)
2022-09-13
Last Update Posted
2026-04-02
Completion Date (Estimated)
2027-12-14
Enrollment (Estimated)
450
Study Type
Interventional
PHASE
Phase 2
Phase 3
Phase 3
Status
Recruiting
Keywords
Cutaneous Lupus Erythematosus (CLE)
Discoid Lupus Erythematosus (DLE)
Systemic Lupus Erythematosus (SLE)
Lupus
Subacute Cutaneous Lupus Erythematosus (SCLE)
Discoid Lupus Erythematosus (DLE)
Systemic Lupus Erythematosus (SLE)
Lupus
Subacute Cutaneous Lupus Erythematosus (SCLE)
Primary Purpose
Treatment
Design Allocation
Randomized
Interventional Model
Parallel
Masking
Quadruple
Arms / Interventions
| Participant Group/Arm | Intervention/Treatment |
|---|---|
ExperimentalPart A (Phase 2): Litifilimab Participants will receive litifilimab subcutaneously (SC) once every 4 weeks (Q4W) from Week 0 to Week 20, with an additional dose of litifilimab at Week 2 during the double-blind placebo-controlled (DBPC) treatment period. Following the DBPC treatment period, participants will receive litifilimab during the extended treatment period (ETP) from Week 24 to Week 48, with an additional dose of litifilimab-matching place...Show More | Litifilimab Administered as specified in the treatment arm. |
Placebo ComparatorPart A (Phase 2): Placebo Participants will receive litifilimab-matching placebo SC Q4W from Week 0 to Week 20, with an additional dose of litifilimab-matching placebo at Week 2 during the DBPC treatment period. Following the DBPC treatment period, participants will receive litifilimab during the ETP from Week 24 to Week 48, with an additional dose of litifilimab at Week 26. | Placebo Administered as specified in the treatment arm. |
ExperimentalPart B (Phase 3): Litifilimab Participants will receive litifilimab SC Q4W from Week 0 to Week 20, with an additional dose of litifilimab at Week 2 during the DBPC treatment period. Following the DBPC treatment period, participants will receive litifilimab during the ETP from Week 24 to Week 48, with an additional dose of litifilimab-matching placebo at Week 26. | Litifilimab Administered as specified in the treatment arm. |
Placebo ComparatorPart B (Phase 3): Placebo Participants will receive litifilimab-matching placebo SC Q4W from Week 0 to Week 20, with an additional dose of litifilimab-matching placebo at Week 2 during the DBPC treatment period. Following the DBPC treatment period, participants will receive litifilimab during the ETP from Week 24 to Week 48, with an additional dose of litifilimab at Week 26. | Placebo Administered as specified in the treatment arm. |
Primary Outcome Measures
Secondary Outcome Measures
| Outcome Measure | Measure Description | Time Frame |
|---|---|---|
Parts A: Percentage of Participants who Achieve a Cutaneous Lupus Activity of Physician's Global Assessment-Revised (CLA-IGA-R) Erythema Score of 0 or 1 | Week 16 | |
Part B: Percentage of Participants who Achieve Cutaneous Lupus Erythematosus Disease Area and Severity Index Activity Score (CLASI-70) Response, Defined as ≥ 70% Decrease in CLASI-A Score From Baseline | Baseline to Week 24 |
| Outcome Measure | Measure Description | Time Frame |
|---|---|---|
Part A: Percentage of Participants With a CLASI-70 Response at Week 52 Among CLASI-70 Responders at Week 16 and Week 24, Respectively, who Were Randomly Assigned to Receive Litifilimab During the DBPC Treatment Period (TP) | Week 52 | |
Part A: Percentage of Participants With CLA-IGA-R Erythema Score of 0 or 1 at Week 52 Among CLA-IGA-R Erythema Responders at Week 16 and Week 24, Respectively, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part A: Percentage of Participants With CLA-IGA-R OMC Score of 0 or 1 and at Least 1 Level of Improvement From Baseline at Week 52 Among CLA-IGA-R OMC Responders at Weeks 16 &24, Respectively, who Were Assigned to Receive Litifilimab in DBPC TP | Week 52 | |
Part A: Percentage of Participants With CLA-IGA-R OMC Score of 0 at Week 52 Among CLA-IGA-R OMC Responders With CLA-IGA-R OMC Score of 0 at Week 16 and Week 24, Respectively, who Were Randomly Assigned to Litifilimab During DBPC TP | Week 52 | |
Part A: Percentage of Participants With CLA-IGA-R Follicular Activity Score of 0 at Week 52 Among CLA-IGA-R Follicular Activity Responders at Week 16 and Week 24, Respectively, who Were Randomly Assigned to Receive Litifilimab in DBPC TP | Week 52 | |
Part A: Percentage of Participants With a CLASI-70 Response at Week 52 Among CLASI-70 Nonresponders at Week 16 and Week 24, Respectively, who Were Randomly Assigned to Receive Placebo During the DBPC TP | Week 52 | |
Part A: Percentage of Participants With a CLA-IGA-R Erythema Score of 0 or 1 at Week 52 Among CLA-IGA-R Erythema Nonresponders at Week 16 and Week 24, Respectively, who Were Randomly Assigned to Receive Placebo During the DBPC TP | Week 52 | |
Part A: Percentage of Participants With CLA-IGA-R OMC Score of 0 or 1 and at Least 1 Level of Improvement From Baseline at Week 52 Among CLA-IGA-R OMC Nonresponders at Weeks 16 and 24, Respectively, who Were Assigned to Receive Placebo in DBPC TP | Week 52 | |
Part A: Percentage of Participants With a CLA-IGA-R OMC Score of 0 at Week 52 Among CLA-IGA-R OMC Nonresponders at Week 16 and Week 24, Respectively, who Were Randomly Assigned to Receive Placebo During the DBPC TP | Week 52 | |
Part A: Percentage of Participants who Have CLA-IGA-R Follicular Activity Score of 0 at Week 52 Among CLA-IGA-R Follicular Activity Nonresponders at Weeks 16 and 24, Respectively, who Were Randomly Assigned to Receive Placebo in DBPC TP | Week 52 | |
Part A: Annualized Mild and Moderate SFI Rate and Annualized Severe SFI Rate Through Week 16 | Up to Week 16 | |
Part A: Absolute Change in Cutaneous Lupus Erythematosus Disease Area and Severity Index Damage (CLASI-D) Score at Week 52 | Baseline to Week 52 | |
Part A: Percent Change in CLASI-D Score | Baseline to Week 52 | |
Part B: Percentage of Participants who Achieve a CLASI A score of 0 to 3 | Week 24 | |
Part B: Percentage of Participants who Achieve a CLA-IGA-R OMC Score of 0 or 1 and at Least 2-Point Improvement From Baseline at Week 24, for Participants who had CLA-IGA-R OMC Score ≥ 2 at Baseline | Week 24 | |
Part B: Percentage of Participants who Achieve a CLA-IGA-R Erythema Score of 0 or 1, at Week 16 and Week 24, Respectively, for Participants in Full Analysis Set (FAS), who had CLA-IGA-R Erythema Score ≥3 and Other OMC Score ≥3 at Baseline | Weeks 16 and 24 | |
Part B: Percentage of Participants who Achieve a CLA-IGA-R OMC Score of 0 or 1, at Week 16 and Week 24, Respectively, for Participants in FAS, who had CLA-IGA-R Erythema Score ≥3 and OMC Score ≥3 at Baseline | Weeks 16 and 24 | |
Part B: Percentage of Participants who Achieve CLA IGA R Erythema Score of 0 or 1 | Up to Week 24 | |
Part B: Percentage of Participants who Achieve at Least 1 Level of Improvement From Baseline in the CLA-IGA-R Erythema Score | Up to Week 24 | |
Part B: Percentage of Participants who Achieve a CLASI-A Score of 0 to 5 | Up to Week 24 | |
Part B: Percentage of Participants who Achieve a CLASI-50a Response, Defined as a ≥ 50% Decrease in Baseline CLASI-A Score in Addition to Achieving Mild Disease Severity With a CLASI-A Score <10 at Week 16 and Week 24, Respectively | Weeks 16 and 24 | |
Part B: Percentage of Participants With a CLASI 70 Response at Week 52 Among CLASI-70 Responders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLASI 50 Response at Week 52 Among CLASI-50 Responders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLASI A 0 to 3 Response at Week 52 Among CLASI-A 0 to 3 Responders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLA IGA R Erythema Score of 0 or 1 at Week 52 Among CLA-IGA-R Erythema Responders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLA IGA R OMC score of 0 at Week 52 Among CLA IGA R OMC Responders With a CLA-IGA-R OMC Score of 0 at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLA IGA-R Follicular Activity Score of 0 at Week 52 Among CLA-IGA-R Follicular Activity Responders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLASI 70 Response at Week 52 Among CLASI-70 Nonresponders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLASI 50 Response at Week 52 Among CLASI-50 Nonresponders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLASI A 0 to 3 Response at Week 52 Among CLASI-A 0 to 3 Nonresponders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLA IGA R Erythema Score of 0 or 1 at Week 52 Among CLA-IGA-R Erythema Nonresponders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLA IGA R OMC score of 0 at Week 52 Among CLA IGA R OMC Nonresponders With a CLA-IGA-R OMC Score of 0 at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Percentage of Participants With a CLA IGA-R Follicular Activity Score of 0 at Week 52 Among CLA-IGA-R Follicular Activity Nonresponders at Week 24, who Were Randomly Assigned to Receive Litifilimab During the DBPC TP | Week 52 | |
Part B: Absolute Change in CLASI-D Score | Week 52 | |
Part B: Percent Change in CLASI-D Score | Week 52 | |
Part B: Change From Baseline in Cutaneous Lupus Erythematosus-Quality of Life (CLE-QoL) Score | Part B: Weeks 16, 24 and 52 | |
Part B: Change From Baseline in Dermatology Life Quality Index (DLQI) Score | Part B: Weeks 16, 24 and 52 | |
Part B: Change From Baseline in Numerical Rating Scale (NRS) for Pain in Skin Rash | Part B: Weeks 16, 24 and 52 | |
Part B: Change From Baseline in NRS for Itch in Skin Rash | Part B: Weeks 16, 24 and 52 | |
Parts A and B: Percentage of Participants who Achieve a CLA-IGA-R Erythema Score of 0 or 1 | Part A: Week 24; Part B: Weeks 16 and 24 | |
Parts A and B: Percentage of Participants who Achieve a CLA-IGA-R Other Morphologic Characteristics (OMC) Score of 0 or 1 and at Least 1 Level of Improvement From Baseline | Part A: Weeks 16 and 24; Part B: Up to Week 24 | |
Parts A and B: Percentage of Participants who Achieve a CLA-IGA-R OMC Score of 0 | Part A: Weeks 16 and 24; Part B: Up to Week 24 | |
Parts A and B: Percentage of Participants With at Least 1 Level of Improvement From Baseline in CLA-IGA-R OMC Score | Part A: Weeks 16 and 24; Part B: Up to Week 24 | |
Parts A and B: Percentage of Participants who Have a CLA-IGA-R Follicular Activity Score of 0 | Part A: Weeks 16 and 24; Part B: Up to Week 24 | |
Parts A and B: Percentage of Participants who Achieve a CLASI-70 Response, Defined as a ≥ 70% Decrease in CLASI-A Score From Baseline | Parts A: Weeks 16 and 24; Part B: Week 12 | |
Parts A and B: Percentage of Participants who Achieve a CLASI-50 Response, Defined as a ≥ 50% Decrease in CLASI-A Score From Baseline | Part A: Weeks 16 and 24; Part B: Weeks 12 and 24 | |
Parts A and B: Percentage of Participants who Achieve a CLASI-A Score of 0 or 1 | Up to Week 24 | |
Parts A and B: Percentage of Participants who Achieve a CLASI-A Score of 0 to 3 | Up to Week 24 | |
Parts A and B: Percentage of Participants who Achieve a CLASI 70 Response | Up to Week 24 | |
Parts A and B: Percentage of Participants who Achieve a CLASI 50 Response | Up to Week 24 | |
Parts A and B: Percentage of Participants who Achieve a 7-Point Reduction From Baseline in CLASI-A Score | Up to Week 24 | |
Parts A and B: Annualized Mild and Moderate Safety of Estrogens in Lupus Erythematosus National Assessment-SLE Disease Activity Index Flare Index Rate and Annualized Severe SFI Rate Through Week 24 | Up to Week 24 | |
Parts A and B: Annualized Mild and Moderate SFI Rate and Annualized Severe SFI Rate Through Week 52 | Up to Week 52 | |
Parts A and B: Number of Participants Experiencing Treatment Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs) | Up to Week 76 | |
Parts A and B: Number of Participants With Anti-Litifilimab Antibodies in Serum During the Study | Up to Week 76 |
Participation Assistant
Eligibility Criteria
Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
- Histologically confirmed (in the past or during the Screening period) diagnosis of CLE with or without systemic manifestations.
- Must have active cutaneous manifestations that meet study criteria.
- Must have a CLASI-A score ≥10.
- Must have an active CLE lesion despite an adequate trial of antimalarial treatment.
- Any active skin conditions other than CLE that may interfere with the study assessments of CLE.
- Diagnosis of mixed connective tissue disease \[(within 1 year of signing the informed consent form (ICF)\] or any history of overlap syndromes of SLE including concomitant presence with rheumatoid arthritis, dermatomyositis and/or polymyositis, systemic sclerosis, psoriatic arthritis, or any other autoimmune disease that may confound the evaluation of the disease activity or the effect of the investigational product. Exceptions for overlap syndrome of SLE include participants with overlap syndrome of SLE with myositis and secondary Sjögren's syndrome at screening is permitted provided the participant also meets the criteria for classification as SLE. A past history of mixed connective tissue disease that over time has developed into a diagnosis of SLE is permitted, provided diagnosis of SLE has been present for at least 1 year.
- Active severe lupus nephritis.
- Active neuropsychiatric SLE.
- Use of intralesional corticosteroids within 1 week prior to Screening and during the study.
- Use of immunosuppressive or disease-modifying treatments for SLE or CLE \[via an oral, intravenous (IV), or SC route\] that were initiated less than 12 weeks prior to screening, have not been at a stable and allowable dose.
NOTE: Other protocol-defined Inclusion/Exclusion criteria may apply
BiogenStudy Central Contact
Contact: US Biogen Clinical Trial Center, 866-633-4636, [email protected]
Contact: Global Biogen Clinical Trial Center, [email protected]
310 Study Locations in 30 Countries
Alabama
Pinnacle Research Group, LLC, Anniston, Alabama, 36207, United States
Contact, 256-236-0055
Vishala L Chindalore, Principal Investigator
Recruiting
UAB Center for Women's Reproductive Health, Birmingham, Alabama, 35233-7340, United States
Contact, 205-502-9960
Lauren Graham, Principal Investigator
Recruiting
Arizona
Arizona Arthritis & Rheumatology Research, PLLC, Phoenix, Arizona, 85032, United States
Contact, 480-443-8400
Saima Chohan, Principal Investigator
Recruiting
California
The Regents of the University of California, La Jolla, California, 92037, United States
Contact, 858-246-2382
Arthur Francis Kavanaugh, Principal Investigator
Recruiting
Dermatology Research Associates, Los Angeles, California, 90045, United States
Contact, 310-337-7171
Howard Lee Sofen, Principal Investigator
Recruiting
Clinical Science Institute, Santa Monica, California, 90404, United States
Completed
Inland Rheumatology Clinical Trials, Inc., Upland, California, 91786, United States
Contact, 909-296-8700
Eric Cheng-Jer Lee, Principal Investigator
Recruiting
Colorado
Denver Arthritis Clinic, Denver, Colorado, 80230, United States
Completed
Florida
Omega Research Debary, LLC, DeBary, Florida, 32713, United States
Contact, 407-988-1075
Kwabena Ayesu, Principal Investigator
Recruiting
Centre for Rheumatology, Immunology and Arthritis, Fort Lauderdale, Florida, 33334, United States
Completed
University of Florida, Gainesville, Florida, 32610, United States
Completed
University of Miami Miller School of Medicine, Miami, Florida, 33125, United States
Contact, 305-542-3535
Andrea Dale Maderal, Principal Investigator
Recruiting
Millennium Medical Research, LLC, Miami, Florida, 33126, United States
Contact, 800-377-2235
Ramon M Moreda, Principal Investigator
Recruiting
Medical Research Center of Miami, Miami, Florida, 33134, United States
Completed
Diverse Clinical Research LLC, Miami, Florida, 33175, United States
Contact, 305-582-7752
Mireya Garcia, Principal Investigator
Recruiting
Charisma Medical and Research Center, Miami Lakes, Florida, 33014, United States
Completed
Leading Edge Dermatology, Plantation, Florida, 33317, United States
Contact, 713-487-8680
Elyse Julian, Principal Investigator
Recruiting
Georgia
Augusta University, Augusta, Georgia, 30912, United States
Completed
Illinois
Rush University Medical Center, Chicago, Illinois, 60612, United States
Completed
OrthoIllinois, Rockford, Illinois, 61114, United States
Completed
Indiana
Dawes Fretzin Clinical Research Group, LLC, Indianapolis, Indiana, 46250, United States
Completed
Kentucky
Equity Medical, Bowling Green, Kentucky, 42104, United States
Contact, 844-378-9633
David J. Johnson, Principal Investigator
Recruiting
Louisiana
LSU Health Sciences Center Shreveport, New Orleans, Louisiana, 70112, United States
Contact, 318-675-5930
Samina Hayat, Principal Investigator
Recruiting
Massachusetts
Tufts Medical Center, Boston, Massachusetts, 02111, United States
Contact, 617-636-0156
Gabriela A Cobos, Principal Investigator
Recruiting
Brigham And Women's Hospital, Boston, Massachusetts, 02115, United States
Contact, 617-732-6378
Joseph F. Merola, Principal Investigator
Recruiting
Essential Dermatology, Natick, Massachusetts, 01760, United States
Completed
Beacon Clinical Research, LLC, Quincy, Massachusetts, 02169, United States
Contact, 781-253-7165
Victoria Kuohung, Principal Investigator
Recruiting
University of Massachusetts, Worcester, Worcester, Massachusetts, 01655, United States
Completed
Michigan
David Fivenson, MD, Dermatology, PLLC, Ann Arbor, Michigan, 48103, United States
Contact, 734-712-3376
David P Fivenson, Principal Investigator
Recruiting
Oakland Hills Dermatology, Auburn Hills, Michigan, 48326, United States
Contact, 248-858-2255
Christofer Buatti, Principal Investigator
Recruiting
AA MRC LLC Ahmed Arif Medical Research Center, Flint, Michigan, 48504, United States
Completed
Revival Research Institute, LLC, Troy, Michigan, 48084, United States
Contact, 248-590-0298
Ali Moiin, Principal Investigator
Recruiting
Missouri
Saint Louis University, St Louis, Missouri, 63110, United States
Contact, 314-256-3454
M Yadira Hurley, Principal Investigator
Recruiting
Nebraska
University of Nebraska Medical Center, Omaha, Nebraska, 68198, United States
Completed
New Mexico
Albuquerque Center For Rheumatology, Albuquerque, New Mexico, 87102, United States
Completed
University of New Mexico School of Medicine, Albuquerque, New Mexico, 87106, United States
Completed
New York
NYU Langone Brooklyn, Brooklyn, New York, 11220, United States
Contact, 929-455-2399
David Harry Goddard, Principal Investigator
Recruiting
Universal Dermatology, PLLC, Fairport, New York, 14450, United States
Contact, 585-275-7546
Brian Poligone, Principal Investigator
Recruiting
Northwell Health, Inc. PRIME, Great Neck, New York, 11021, United States
Contact, 516-708-2557
Richard A Furie, Principal Investigator
Recruiting
Columbia University Medical center, New York, New York, 10032, United States
Contact, 212-305-4308
Laura B Geraldino Pardilla, Principal Investigator
Recruiting
North Carolina
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27514, United States
Contact, 919-843-6619
Saira Zafar Sheikh, Principal Investigator
Recruiting
Duke Dermatology South Durham, Durham, North Carolina, 27710, United States
Contact, 919-385-7546
Anne Louise Marano, Principal Investigator
Recruiting
Medication Management, LLC, Greensboro, North Carolina, 27405, United States
Completed
Ohio
University of Cincinnati Department of Dermatology, Cincinnati, Ohio, 45219, United States
Contact, 513-475-7631
Alan B. Fleischer, Principal Investigator
Recruiting
University Hospitals Cleveland Medical Center, Cleveland, Ohio, 44106, United States
Completed
Ohio State University, Columbus, Ohio, 43210, United States
Completed
Pennsylvania
Penn State University Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033, United States
Completed
University of Pennsylvania, Philadelphia, Pennsylvania, 19104, United States
Contact, 215-615-2940
Victoria Patricia Werth, Principal Investigator
Recruiting
Tennessee
Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States
Contact, 615-936-4072
Narender Annapureddy, Principal Investigator
Recruiting
Texas
Austin Regional Clinic, P.A., Austin, Texas, 78731, United States
Contact, 512-344-0362
Tina C. Bunch, Principal Investigator
Recruiting
Precision Comprehensive Clinical Research Solutions, Colleyville, Texas, 76034, United States
Contact, 972-299-8399
Dhiman Basu, Principal Investigator
Recruiting
Metroplex Clinical Research Center, LLC, Dallas, Texas, 75231, United States
Completed
UT Southwestern Medical Center, Dallas, Texas, 75390-8896, United States
Contact, 214-645-2400
Benjamin Chong, Principal Investigator
Recruiting
North Texas Center for Clinical Research, Frisco, Texas, 75034, United States
Contact, 888-635-0552
Timothy Gale Rodgers, Principal Investigator
Recruiting
UTMB Department of Dermatology, Galveston, Texas, 77555-0583, United States
Contact, 409-772-5047
Bernard R Gibson, Principal Investigator
Recruiting
University of Texas Health Science Center at Houston, Houston, Texas, 77054, United States
Completed
Arthritis & Osteoporosis Clinic, Waco, Texas, 76710, United States
Contact, 254-755-4584
HS Eugene Fung, Principal Investigator
Recruiting
Velocity Clinical Research Waco, Waco, Texas, 76710, United States
Completed
Utah
University of Utah Health Sciences Center, Salt Lake City, Utah, 84132, United States
Contact, 801-581-2955
Jamie W. Rhoads, Principal Investigator
Recruiting
Virginia
Open Door Clinical Research, Blacksburg, Virginia, 24060, United States
Contact, 540-476-8966
Daniel Hurd, Principal Investigator
Recruiting
West End Dermatology Associates, Richmond, Virginia, 23233, United States
Completed
Alberta
Laser Rejuvenation Clinics, Inc., Calgary, Alberta, T2W 4X9, Canada
Contact, 4032866888
Paul Kuzel, Principal Investigator
Recruiting
Laster Rejuvenation Clinics Edmonton D.T. Inc., Edmonton, Alberta, T5J 3S9, Canada
Contact, 7804251212
Maninder Longowal, Principal Investigator
Recruiting
Ontario
Medicor Research Inc, Greater Sudbury, Ontario, P3C 1X3, Canada
Completed
Dermatology Ottawa Research Centre, Ottawa, Ontario, K2C 3N2, Canada
Completed
Quebec
DIEX Recherche Sherbrooke Inc., Sherbrooke, Quebec, J1L 0H8, Canada
Contact, 8193462887
Daniel Minier, Principal Investigator
Recruiting
Dr. Samuel Sanchez PSC, Caguas, 00727, Puerto Rico
Completed
GCM Medical Group PSC - Hato Rey, San Juan, 917, Puerto Rico
Contact, 7879362100
Jose R Gonzalez Chavez, Principal Investigator
Recruiting
Buenos Aires
CINME - Centro De Investigaciones Metabolicas, CABA, Buenos Aires, C1056ABI, Argentina
Completed
Centro de Investigaciones Medicas Mar del Plata, Mar del Plata, Buenos Aires, 7600, Argentina
Contact, 5492235603218
Gladys Alicia Testa, Principal Investigator
Recruiting
Instituto de Investigaciones Clinicas Quilmes, Quilmes, Buenos Aires, B1878GEG, Argentina
Contact, 5491135804733
Jose Luis Velasco Zamora, Principal Investigator
Recruiting
Centro de Investigaciones San Miguel, San Miguel, Buenos Aires, 1663, Argentina
Contact, +5491153342038
Adrian Alejandro Schejtman, Principal Investigator
Recruiting
Ciudad Autonoma Buenos Aires
APRILLUS Asistencia e Investigacion, Buenos Aires, Ciudad Autonoma Buenos Aires, C1406AGA, Argentina
Contact, 541567415099
Pablo Alejandro Mannucci Walter, Principal Investigator
Recruiting
Fundacion Respirar, Buenos Aires, Ciudad Autonoma Buenos Aires, C1426ABO, Argentina
Contact, 541167063598
Alejandro Arroyo, Principal Investigator
Recruiting
Mendoza Province
Consultorio Alto Dorrego, Villa Nueva, Mendoza Province, CP 5519, Argentina
Contact, +5492615988653
Matias Manuel Benavente, Principal Investigator
Recruiting
Santa Fe Province
Instituto CAICI, Rosario, Santa Fe Province, S2000PBJ, Argentina
Contact, 543413000000
Carolina Irma Dieguez, Principal Investigator
Recruiting
Tucumán Province
Clinica Mayo de Urgencias Medicas Cruz Blanca SRL, San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Contact, 543814304423
Francisco Colombres, Principal Investigator
Recruiting
Centro de Investigaciones Medicas Tucuman, San Miguel de Tucumán, Tucumán Province, T4000AXL, Argentina
Contact, 543814200180
Walter Javier Spindler, Principal Investigator
Recruiting
Investigaciones Clinicas Tucuman, San Miguel de Tucumán, Tucumán Province, T4000ICL, Argentina
Contact, 5493815932070
Veronica Ines Bellomio, Principal Investigator
Recruiting
Hospital Italiano de La Plata, Buenos Aires, B1900AXI, Argentina
Contact, 5492215928029
Sebastian Juan Magri, Principal Investigator
Recruiting
Hospital Italiano de Buenos Aires, Ciudad Autonoma Buenos Aires, C1199ABB, Argentina
Contact, +541148274281
Luis Daniel Mazzuoccolo, Principal Investigator
Recruiting
Centro Privado de Medicina Familiar - Mind Out Research, Ciudad Autonoma Buenos Aires, C1417, Argentina
Contact, 5491149273479
Leonardo Naftal, Principal Investigator
Recruiting
Clinica Adventista Belgrano, Ciudad Autonoma Buenos Aires, C1430EGF, Argentina
Contact, 541145445522
Federico Javier Ariel, Principal Investigator
Recruiting
Instituto de Reumatologia, Mendoza, M5500, Argentina
Contact, 5492615440980
Alfredo Borgia, Principal Investigator
Recruiting
CER San Juan Centro Polivalente de Asistencia e Inv. Clinica, San Juan, 5400, Argentina
Contact, 5492645655194
Jose Luis Cristian Moreno, Principal Investigator
Recruiting
Vlaams-Brabant
UZ Leuven, Leuven, Vlaams-Brabant, 03000, Belgium
Contact, +3216337950
Petra De Haes, Principal Investigator
Recruiting
Cliniques Universitaires Saint-Luc, Brussels, 1200, Belgium
Contact, +3227641472
Pierre Dominique Ghislain, Principal Investigator
Recruiting
Universitair Ziekenhuis Gent, Ghent, 9000, Belgium
Contact, +3293322287
Reinhart Speeckaert, Principal Investigator
Recruiting
Centre Hospitalier Universitaire de Liege, Liège, 4000, Belgium
Contact, +3243667232
Arjen Fokko Nikkels, Principal Investigator
Recruiting
Ceará
Integrare Terapêutica, Fortaleza, Ceará, 60125-000, Brazil
Contact, +558530446556
Max Victor Carioca de Freitas, Principal Investigator
Recruiting
HUWC - UFC - Hospital Universitário Walter Cantídio - Universidade Federal do Ceará, Fortaleza, Ceará, 60430-370, Brazil
Contact, 5585991711566
Vanessa Beatriz de Vasconcelos Marques, Principal Investigator
Recruiting
Espírito Santo
CEDOES - Diagnóstico e Pesquisa, Vitória, Espírito Santo, 29055-450, Brazil
Completed
Estado de Bahia
Clínica SER da Bahia, Salvador, Estado de Bahia, 40150-150, Brazil
Contact, 5571990000000
Mittermayer Barreto Santiago, Principal Investigator
Recruiting
Federal District
L2IP - Instituto de Pesquisas Clínicas Ltda., Brasília, Federal District, 70200-730, Brazil
Contact, 556134454300
Eduardo Freire Vasconcellos, Principal Investigator
Recruiting
Mato Grosso
IPC MT Instituto de Pesquisas Clinicas do Mato Grosso, Santo Ângelo, Mato Grosso, 78020-500, Brazil
Contact, 5565999814014
Luiz Sergio Guedes Barbosa, Principal Investigator
Recruiting
Minas Gerais
Santa Casa de Misericordia de Belo Horizonte, Belo Horizonte, Minas Gerais, 30150-221, Brazil
Contact, 553198651041
Claudia Lopes Santoro Neiva, Principal Investigator
Recruiting
Clinica Pulsus, Belo Horizonte, Minas Gerais, 30180-065, Brazil
Contact, +553134099255
Fabiana de Miranda Moura dos Santos, Principal Investigator
Recruiting
CMiP - Centro Mineiro de Pesquisa, Juiz de Fora, Minas Gerais, 36010-570, Brazil
Contact, 553233000000
Silviane Vassalo, Principal Investigator
Recruiting
Rio Do Janeiro
Instituto Brasil de Pesquisa Clínica-IBPCLIN S/A, Rio de Janeiro, Rio Do Janeiro, 20241-180, Brazil
Contact, 552125277979
Jaqueline Barbeito de Vasconcellos, Principal Investigator
Recruiting
IDERJ - Instituto de Dermatologia e Estética do Brasil Ltda, Rio de Janeiro, Rio Do Janeiro, 22470-220, Brazil
Contact, 552125000000
Luna Azulay Abulafia, Principal Investigator
Recruiting
Rio Grande do Sul
Hospital Bruno Born, Lajeado, Rio Grande do Sul, 95900-000, Brazil
Contact, 555137147500
Jussara Marilu Bohn, Principal Investigator
Recruiting
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Contact, 555133000000
Odirlei André Monticielo, Principal Investigator
Recruiting
Nucleo de Pesquisa Clinica do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, 90430001, Brazil
Contact, 555137796400
Cecilia Viola Varella da Costa, Principal Investigator
Recruiting
LMK Serviços Médicos S/S Ltda, Porto Alegre, Rio Grande do Sul, 90480-000, Brazil
Contact, 555133205057
Mauro Waldemar Keiserman, Principal Investigator
Recruiting
Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, 90560032, Brazil
Contact, 51997393212
Tamara Mucenic, Principal Investigator
Recruiting
Rondônia
IPES - Instituto de Pesquisa e Educação em Saúde, Porto Velho, Rondônia, 76804366, Brazil
Contact, +5569993787257
Samila Alves Da Silva Paschoal, Principal Investigator
Recruiting
São Paulo
CEMEC - Centro Multidisciplinar de Estudos Clínicos, São Bernardo do Campo, São Paulo, 09715-090, Brazil
Contact, 551149304243
Paulo Ricardo Criado, Principal Investigator
Recruiting
CEPIC - Centro Paulista de Investigação Clínica e Serviços Médicos, São Paulo, São Paulo, 04266-010, Brazil
Contact, 551122713450
Flora Maria D'Andrea Marcolino, Principal Investigator
Recruiting
A2Z Clinical Centro Avancado de Pesquisa Clinica, Valinhos, São Paulo, 13271-130, Brazil
Contact, +5511993365287
Alisson Aliel Vigano Pugliesi, Principal Investigator
Recruiting
RDSS Ricardo Diaz Scientific Solution, São Paulo, 04037-030, Brazil
Contact, +5521997994412
Roberta Queiroz Graumam, Principal Investigator
Recruiting
Gabrovo
DCC-1-Sevlievo EOOD, Sevlievo, Gabrovo, 5400, Bulgaria
Contact, +359893028511
Dimitar Nikolov, Principal Investigator
Recruiting
DCC 'Sveti Georgi' EOOD, Haskovo, 6300, Bulgaria
Contact, +359888325384
Irida Vasileva, Principal Investigator
Recruiting
Medical center Medconsult Pleven OOD, Pleven, 5800, Bulgaria
Completed
UMHAT 'Dr. Georgi Stranski', EAD, Pleven, 5800, Bulgaria
Completed
DCC 1 - Ruse, EOOD, Rousse, 7002, Bulgaria
Completed
Ambulatory for Specialized Medical Help - skin and venereal diseases, Sofia, 1407, Bulgaria
Contact, +359888207206
Ivan Botev, Principal Investigator
Recruiting
DCC 'Alexandrovska', EOOD, Sofia, 1431, Bulgaria
Contact, +359888565564
Snejina Vassileva, Principal Investigator
Recruiting
DCC 'Alexandrovska', EOOD, Sofia, 1431, Bulgaria
Contact, 359888208421
Petyo Brezoev, Principal Investigator
Recruiting
DCC Focus 5 - MEOH OOD, Sofia, 1463, Bulgaria
Completed
Military Medical Academy - MHAT - Sofia, Sofia, 1606, Bulgaria
Completed
Centro Medico SkinMed, Las Condes, 7580206, Chile
Contact, 56232746600
Juan Walter Gubelin Harcha, Principal Investigator
Recruiting
Dermacross, Santiago, 66901, Chile
Contact, 56229540251
Claudia Paz De La Cruz, Principal Investigator
Recruiting
BioMedica Research Group, Santiago, 7500710, Chile
Contact, 56992323955
Elizabeth Jean Moreno Goio, Principal Investigator
Recruiting
CeCim Biocinetic, Santiago, 8331143, Chile
Contact, 56226965804
Darwin Yañez Pizarro, Principal Investigator
Recruiting
CIEC - Centro Internacional de Estudios Clínicos, Santiago, 8420383, Chile
Contact, 56227357954
Fernando Valenzuela, Principal Investigator
Recruiting
Clinical Research Chile SpA., Valdivia, 5090000, Chile
Contact, 56940601237
Alvaro Andres San Martin Leal, Principal Investigator
Recruiting
Oncocentro APYS, Viña del Mar, 2520598, Chile
Contact, 56322675546
Renato Eduardo Jimenez Calabrese, Principal Investigator
Recruiting
Beijing Municipality
Beijing Tongren Hospital, Capital Medical University, Beijing, Beijing Municipality, 100730, China
Recruiting
Peking Union Medical College Hospital, Beijing, Beijing Municipality, 100730, China
Recruiting
Chongqing Municipality
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing Municipality, 400016, China
Recruiting
Fujian
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350005, China
Recruiting
Guangdong
Dongguan People's Hospital, Dongguan, Guangdong, 523059, China
Recruiting
Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, 510515, China
Recruiting
Shenzhen Second People's Hospital, Shenzhen, Guangdong, 518029, China
Recruiting
Zhongshan TCM Hospital, Zhongshan, Guangdong, 528400, China
Recruiting
Guangzhou
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangzhou, 510120, China
Recruiting
Henan
Nanyang First People's Hospital, Nanyang, Henan, 473004, China
Completed
Henan Provincial People's Hospital, Zhengzhou, Henan, 450003, China
Recruiting
Hu'nan
Xiangya Hospital of Central South University, Changsha, Hu'nan, 410008, China
Recruiting
The second Xiangya Hospital of Central South University, Changsha, Hu'nan, 410011, China
Recruiting
Inner Mongolia
The First Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia, 014010, China
Recruiting
Jiangsu
Hospital for Skin Diseases, Chinese Academy of Medical Sciences, Nanjing, Jiangsu, 210042, China
Recruiting
Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, China
Completed
Jilin
The First Hospital of Jilin University, Changchun, Jilin, 130021, China
Recruiting
Shandong
Qilu Hospital of Shandong University, Jinan, Shandong, 250012, China
Completed
Shanghai Municipality
Ruijin Hospital of Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai Municipality, 200011, China
Recruiting
Zhongshan Hospital Fudan University, Shanghai, Shanghai Municipality, 200032, China
Recruiting
Shanghai Skin Disease Hospital, Shanghai, Shanghai Municipality, 200443, China
Recruiting
Yunnan
The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, 650101, China
Recruiting
Zhejiang
The First Affiliated Hospital of Zhejiang University school of medicine, Hangzhou, Zhejiang, 310003, China
Recruiting
Hangzhou First People's Hospital, Hangzhou, Zhejiang, 310006, China
Recruiting
Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China
Recruiting
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China
Recruiting
Atlántico
Centro de Investigacion Medico Asistencial S.A.S, Barranquilla, Atlántico, 80020, Colombia
Recruiting
Cundinamarca
Healthy Medical Center, Zipaquirá, Cundinamarca, 250252, Colombia
Recruiting
Santander Department
Servimed S.A.S., Bucaramanga, Santander Department, 680003, Colombia
Recruiting
Centro de Investigacion en Reumatologia y Especialidades Medicas SAS. CIREEM, Bogotá, 110221, Colombia
Recruiting
Alpes Maritimes
CHU Nice - Hopital de l Archet, Nice, Alpes Maritimes, 6200, France
Contact, 33492036070
Florence Le Duff, Principal Investigator
Recruiting
Bouches-du-Rhône
Hôpital de la Timone, Marseille, Bouches-du-Rhône, 13385, France
Completed
Calvados
CHU de Caen - Hopital de la Cote de Nacre, Caen, Calvados, 14033, France
Contact, 33231272510
Diane Kottler, Principal Investigator
Recruiting
Doubs
CHU Besançon - Hôpital Jean Minjoz, Besançon, Doubs, 25030, France
Contact, 33381218102
Julie Castagna, Principal Investigator
Recruiting
Haute Garonne
Hopital Larrey, Toulouse, Haute Garonne, 31059, France
Contact, 33567778135
Cristina Bulai Livideanu, Principal Investigator
Recruiting
Hauts De Seine
Hôpital Privé d'Antony, Antony, Hauts De Seine, 92160, France
Completed
Herault
Hopital Saint Eloi, Montpellier, Herault, 34295, France
Contact, 33467336906
Didier Bessis, Principal Investigator
Recruiting
Nord
Hopital Claude Huriez - CHU Lille, Lille, Nord, 59037, France
Contact, +33320444193
Delphine Staumont Salle, Principal Investigator
Recruiting
Paris
Hôpital Saint-Louis, Cedex 10, Paris, 75475, France
Contact, 33142499961
Jean-David Bouaziz, Principal Investigator
Recruiting
Rhone
Hopital Edouard Herriot - CHU Lyon, Lyon, Rhone, 69003, France
Completed
Hopital Tenon, Paris, 75020, France
Contact, 33156017221
Francois Chasset, Principal Investigator
Recruiting
Baden-Wurttemberg
Universitaetsklinikum Heidelberg, Heidelberg, Baden-Wurttemberg, 69120, Germany
Completed
Universitaetsklinikum Tuebingen, Tübingen, Baden-Wurttemberg, 72076, Germany
Contact, +4970712986745
Matthias Hahn, Principal Investigator
Recruiting
Bavaria
Universitaetsklinikum Erlangen, Erlangen, Bavaria, 91054, Germany
Contact, 4991318533851
Michael Sticherling, Principal Investigator
Recruiting
LMU-Campus Innenstadt, Munich, Bavaria, 80336, Germany
Contact, +498941403220
Felix Lauffer, Principal Investigator
Recruiting
Klinikum rechts der Isar der TU Muenchen, Munich, Bavaria, 80802, Germany
Contact, +498941403177
Danielle Rogner, Principal Investigator
Recruiting
Universitaetsklinikum Regensburg, Regensburg, Bavaria, 93053, Germany
Contact, +499419449610
Bernadett Kurz, Principal Investigator
Recruiting
Universitaetsklinikum Wuerzburg, Würzburg, Bavaria, 97080, Germany
Contact, +4993120126351
Matthias Goebeler, Principal Investigator
Recruiting
Lower Saxony
Fachklinik Bad Bentheim Dermatologie, Bad Bentheim, Lower Saxony, 48455, Germany
Contact, 495922745270
Athanasios Tsianakas, Principal Investigator
Recruiting
Elbekliniken Buxtehude GmbH, Buxtehude, Lower Saxony, 21614, Germany
Contact, 4941617036005
Andreas Kleinheinz, Principal Investigator
Recruiting
Klinikum Oldenburg AoeR, Oldenburg, Lower Saxony, 26133, Germany
Contact, 4944140372854
Nikolaos Patsinakidis, Principal Investigator
Recruiting
North Rhine-Westphalia
Universitaetsklinikum Aachen AoeR, Aachen, North Rhine-Westphalia, 52074, Germany
Contact, 492418088331
Amir Yazdi, Principal Investigator
Recruiting
Universitaetsklinikum Bonn AoeR, Bonn, North Rhine-Westphalia, 53127, Germany
Completed
Universitaetsklinikum Duesseldorf AoeR, Düsseldorf, North Rhine-Westphalia, 40225, Germany
Contact, +492118117608
Stephan Meller, Principal Investigator
Recruiting
Universitaetsklinikum Muenster, Münster, North Rhine-Westphalia, 48149, Germany
Contact, 492518356501
Kerstin Steinbrink, Principal Investigator
Recruiting
Saxony
Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Saxony, 1307, Germany
Contact, 493514582344
Claudia Guenther, Principal Investigator
Recruiting
Saxony-Anhalt
Universitaetsklinikum Halle (Saale), Halle, Saxony-Anhalt, 6120, Germany
Contact, 493455573933
Johannes Wohlrab, Principal Investigator
Recruiting
Schleswig-Holstein
Universitaetsklinikum Schleswig-Holstein - Campus Kiel, Kiel, Schleswig-Holstein, 24105, Germany
Completed
Charité - Campus Charité Mitte, Berlin, 10117, Germany
Contact, 4930450518105
Margitta Worm, Principal Investigator
Recruiting
Semmelweis Egyetem, Budapest, 1085, Hungary
Contact, +36208258870
Peter Hollo, Principal Investigator
Recruiting
Pecsi Tudomanyegyetem, Pécs, 7632, Hungary
Contact, 3639161691
Anita Hanyecz, Principal Investigator
Recruiting
Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont, Szeged, 6720, Hungary
Contact, +3662545277
Rolland Peter Gyulai, Principal Investigator
Recruiting
Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi IRCCS, Bologna, 40138, Italy
Contact, 39512144847
Michelangelo La Placa, Principal Investigator
Recruiting
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili), Brescia, 25123, Italy
Contact, 39303995307
Piergiacomo Calzavara Pinton, Principal Investigator
Recruiting
Università degli studi di Firenze, Florence, 50121, Italy
Contact, 39556939670
Marzia Caproni, Principal Investigator
Recruiting
IRCCS Ospedale Policlinico San Martino, Genova, 16132, Italy
Contact, 39103626430
Emanuele Claudio Cozzani, Principal Investigator
Recruiting
Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy
Contact, 39255036289
Angelo Valerio Marzano, Principal Investigator
Recruiting
Ospedale San Raffaele, Milan, 20132, Italy
Contact, 39226434683
Lorenzo Dagna, Principal Investigator
Recruiting
Azienda Ospedaliera Universitaria Policlinico 'Federico II', Naples, 80131, Italy
Completed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, 137, Italy
Contact, 39630154798
Clara De Simone, Principal Investigator
Recruiting
Aichi-ken
JCHO Chukyo Hospital, Nagoya, Aichi-ken, 457-8510, Japan
Recruiting
NHO Nagoya Medical Center, Nagoya, Aichi-ken, 460-0001, Japan
Recruiting
Fujita Health University Hospital, Toyoake-shi, Aichi-ken, 470-1192, Japan
Recruiting
Aomori
Aomori Prefectural Central Hospital, Aomori, Aomori, 030-8553, Japan
Recruiting
Chiba
Juntendo University Urayasu Hospital, Urayasu-shi, Chiba, 279-0021, Japan
Recruiting
Fukui
University of Fukui Hospital, Yoshida-gun, Fukui, 910-1193, Japan
Recruiting
Fukuoka
Hospital of the University of Occupational and Environmental Health, Kitakyushu-shi, Fukuoka, 807-8556, Japan
Recruiting
Hokkaido
Hokkaido University Hospital, Sapporo, Hokkaido, 060-8648, Japan
Recruiting
Hyōgo
Kakogawa Central City Hospital, Kakogawa-shi, Hyōgo, 675-8611, Japan
Recruiting
Kita Harima Medical Center, Ono-shi, Hyōgo, 675-1392, Japan
Completed
Ishikawa-ken
Kanazawa University Hospital, Kanazawa, Ishikawa-ken, 920-8641, Japan
Recruiting
Kanagawa
St. Marianna University Hospital, Kawasaki-shi, Kanagawa, 216-8511, Japan
Recruiting
Yokohama City University Medical Center, Yokohama, Kanagawa, 232-0024, Japan
Recruiting
Yokohama City University Hospital, Yokohama, Kanagawa, 236-0004, Japan
Recruiting
NHO Yokohama Medical Center, Yokohama, Kanagawa, 245-8575, Japan
Recruiting
Kumamoto
Kumamoto University Hospital, Kumamoto, Kumamoto, 860-8556, Japan
Recruiting
Miyagi
Tohoku University Hospital, Sendai, Miyagi, 980-8574, Japan
Recruiting
Nagasaki
Nagasaki University Hospital, Nagasaki, Nagasaki, 852-8501, Japan
Recruiting
Niigata
Niigata University Medical & Dental Hospital, Niigata, Niigata, 951-8520, Japan
Recruiting
Okayama-ken
Japanese Red Cross Okayama Hospital, Okayama, Okayama-ken, 700-8607, Japan
Recruiting
Osaka
NHO Osaka Minami Medical Center, Kawachinagano-shi, Osaka, 586-8521, Japan
Recruiting
Daini Osaka Police Hospital, Osaka, Osaka, 543-8922, Japan
Recruiting
Kindai University Hospital, Osakasayama-shi, Osaka, 589-8511, Japan
Recruiting
Osaka University Hospital, Suita-shi, Osaka, 565-0871, Japan
Recruiting
Takatsuki Red Cross Hospital, Takatsuki-shi, Osaka, 569-1096, Japan
Recruiting
Shiga
Shiga University of Medical Science Hospital, Ōtsu, Shiga, 520-2192, Japan
Recruiting
Shimane
Shimane University Hospital, Izumo-shi, Shimane, 693-8501, Japan
Recruiting
Tokyo-To
Teikyo University Hospital, Itabashi-ku, Tokyo-To, 173-8606, Japan
Recruiting
Showa University East Hospital, Shinagawa-ku, Tokyo-To, 142-0054, Japan
Recruiting
Wakayama
Wakayama Medical University Hospital, Wakayama, Wakayama, 641-8510, Japan
Recruiting
Jalisco
Centro de investigacion medica y reumatologia, Guadalajara, Jalisco, 44959, Mexico
Contact, 523333910401
Jorge Enrique Aguilar Arreola, Principal Investigator
Recruiting
Mexico City
Centro de Investigacion Clínica GRAMEL S.C, Mexico City, Mexico City, 3720, Mexico
Contact, 525544274848
Carlos Tzalam Vega Nava, Principal Investigator
Recruiting
Clinstile, S.A. de C.V., Mexico City, Mexico City, 6700, Mexico
Contact, 525552561496
Favio Edmundo Enriquez Sosa, Principal Investigator
Recruiting
Morelos
Consultorio Privado Dr. Miguel Cortes Hernandez, Cuernavaca, Morelos, 62448, Mexico
Contact, 527773137932
Miguel Cortes Hernandez, Principal Investigator
Recruiting
Yucatán
Medical Care & Research SA de CV, Mérida, Yucatán, 97070, Mexico
Contact, 529993226891
Aaron Alejandro Barrera Rodriguez, Principal Investigator
Recruiting
Derma Norte del Bajio S.C., Aguascalientes, 20127, Mexico
Contact, 524499143079
Eduardo David Poletti Vazquez, Principal Investigator
Recruiting
Investigacion y Biomedicina de Chihuahua, S.C., Chihuahua City, 31000, Mexico
Contact, 5216141961278
Cesar Francisco Pacheco Tena, Principal Investigator
Recruiting
ACQ MEDIC SAC - Centro de Investigacion Clinica Inmunoreumatologia, Lima, Lima 11, Peru
Contact, +511999096916
Armando Calvo Quiroz, Principal Investigator
Recruiting
Invest Clinicas Sac Inst de Ginecologia y Reproduccion, Lima, Lima 33, Peru
Contact, +51980802519
Julia Elena Calderon Gallegos, Principal Investigator
Recruiting
Pampanga
The Medical City Clark, Mabalacat, Pampanga, 2023, Philippines
Recruiting
Cebu Doctors University Hospital, Cebu City, 6000, Philippines
Recruiting
Mary Mediatrix Medical Center, Lipa City, 4217, Philippines
Recruiting
Medical Center Manila, Manila, 1000, Philippines
Recruiting
Philippine General Hospital, Manila, 1000, Philippines
Recruiting
Jose R. Reyes Memorial Medical Center, Manila, 1012, Philippines
Recruiting
St. Luke's Medical Center, Quezon City, 1102, Philippines
Recruiting
Far Eastern University - Dr. Nicanor Reyes Medical Foundation, Quezon City, Metro Manila, 1118, Philippines
Recruiting
Ilocos Training and Regional Medical Center, San Fenando, La Union, 2500, Philippines
Recruiting
DERMEDIC Jacek Zdybski, Kielce, 25-553, Poland
Contact, +48601936924
Jacek Zdybski, Principal Investigator
Recruiting
SPZOZ Szpital Uniwersytecki w Krakowie, Krakow, 31-501, Poland
Completed
Promed P.Lach R.Glowacki spolka jawna, Centrum Medyczne PROMED, Krakow, 31-513, Poland
Contact, +48122954139
Ewa Gorecka, Principal Investigator
Recruiting
Specjalistyczny Gabinet Dermatologiczny Aplikacyjno-Badawczy Marek Brzewski, Krakow, 31-530, Poland
Completed
MT Medic Specjalistyczna Praktyka Lekarska Tomasz Stapinski, Krosno, 38-400, Poland
Contact, +48501649474
Anna Rajchel, Principal Investigator
Recruiting
Dermoklinika Centrum Medyczne SC M Kierstan J Narbutt A Lesiak, Lodz, 90-436, Poland
Contact, 48692065698
Joanna Narbutt, Principal Investigator
Recruiting
Kliniczny Szpital Wojewodzki nr 1 im.F.Chopina, Rzeszów, 35-055, Poland
Contact, 48717842292
Adam Andrzej Reich, Principal Investigator
Recruiting
MICS Centrum Medyczne Warszawa, Warsaw, 00-874, Poland
Contact, +48608552294
Katarzyna Romanowska Prochnicka, Principal Investigator
Recruiting
Szpital Kliniczny Dzieciatka Jezus, Warsaw, 02-008, Poland
Contact, 48225021324
Lidia Rudnicka, Principal Investigator
Recruiting
Royalderm, Warsaw, 02-962, Poland
Contact, 48601316460
Witold Owczarek, Principal Investigator
Recruiting
Cityclinic Przychodnia Lekarsko-Psychologiczna Matusiak Spółka Partnerska, Wroclaw, 50-566, Poland
Completed
Centro Hospitalar e Universitário de Coimbra, E.P.E (HUC), Coimbra, 3000-075, Portugal
Contact, 351239000000
Margarida Goncalo, Principal Investigator
Recruiting
Hospital de Egas Moniz, Lisbon, 1349-019, Portugal
Contact, 351210431000
Fernando Pimentel Dos Santos, Principal Investigator
Recruiting
Hospital CUF Descobertas, Lisbon, 1998-018, Portugal
Contact, 351210025200
Pedro Mendes Bastos, Principal Investigator
Recruiting
Centro Hospitalar Universitártio do Porto, E.P.E., Porto, 4099-001, Portugal
Completed
Unidade Local de Saúde do Alto Minho, E.P.E., Viana do Castelo, 4904-858, Portugal
Completed
King Faisal Specialist Hospital & Research Center, Riyadh, 11211, Saudi Arabia
Completed
King Saud University, Riyadh, 11461, Saudi Arabia
Contact, 96614670000
Ibrahim Ali Almaghlouth, Principal Investigator
Recruiting
Institute of Rheumatology, Belgrade, 11000, Serbia
Contact, 381113600801
Goran Radunovic, Principal Investigator
Recruiting
University Clinical Center of Serbia, Belgrade, 11000, Serbia
Contact, 381113663700
Snezana Arandjelovic, Principal Investigator
Recruiting
University Clinical Center Kragujevac, Kragujevac, 34000, Serbia
Contact, 381641750795
Mirjana Veselinovic, Principal Investigator
Recruiting
Clinical Center of Vojvodina, Novi Sad, 21000, Serbia
Contact, 381648000000
Ljuba Vujanovic, Principal Investigator
Recruiting
Artromac n.o., Košice, 4011, Slovakia
Contact, 421911900704
Zelmira Macejova, Principal Investigator
Recruiting
Narodny ustav reumatickych chorob, Piešťany, 92112, Slovakia
Completed
Gyeonggi-do
Korea University Ansan Hospital, Ansan-si, Gyeonggi-do, 15355, South Korea
Recruiting
Ajou University Hospital, Suwon, Gyeonggi-do, 16499, South Korea
Recruiting
Chungnam National University Hospital, Daejeon, 35015, South Korea
Recruiting
Chonnam National University Hospital, Gwangju, 61469, South Korea
Completed
Severance Hospital, Yonsei University Health System, Seoul, 3722, South Korea
Recruiting
Hanyang University Seoul Hospital, Seoul, 4763, South Korea
Recruiting
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, 6591, South Korea
Completed
Barcelona
Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, 8916, Spain
Completed
Cantabria
Hospital Universitario Rio Hortega, Valladolid, Cantabria, 47012, Spain
Contact, 34983420400
Maria Julia Barbado Ajo, Principal Investigator
Recruiting
Castellón
Hospital General de Castellon, Castellon, Castellón, 12004, Spain
Contact, +34964725210
Maria Arantzazu Conesa Mateos, Principal Investigator
Recruiting
Madrid
Hospital Universitario Fundacion Alcorcon, Alcorcón, Madrid, 28922, Spain
Completed
Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, 28222, Spain
Contact, 34911916481
Rita Cabeza Martinez, Principal Investigator
Recruiting
Complejo Hospitalario Universitario A Coruña, A Coruña, 15006, Spain
Contact, 34981176399
Francisco Javier Blanco Garcia, Principal Investigator
Recruiting
Hospital Universitari Vall d'Hebron - VHIR, Barcelona, 08035, Spain
Contact, +34934894171
Josefina Cortes Hernandez, Principal Investigator
Recruiting
Hospital del Mar, Barcelona, 8003, Spain
Contact, 34932483380
Irene Garcia Diez, Principal Investigator
Recruiting
Hospital de la Santa Creu i Sant Pau, Barcelona, 8041, Spain
Contact, 34935537007
Esther Roe Crespo, Principal Investigator
Recruiting
Hospital Universitario Reina Sofia, Córdoba, 14004, Spain
Contact, 34606887057
Juan Alberto Ruano Ruiz, Principal Investigator
Recruiting
Hospital Universitario Virgen del Rocio, Seville, 41013, Spain
Contact, 34955012000
Enrique Jorquera Barquero, Principal Investigator
Recruiting
Karolinska Universitetssjukhuset - Solna, Stockholm, 17176, Sweden
Contact, 46851770000
Filippa Nyberg, Principal Investigator
Recruiting
Canton of Zurich
Universitaetsspital Zuerich, Zurich-Flughafen, Canton of Zurich, 8058, Switzerland
Contact, 41432539940
Julia-Tatjana Maul, Principal Investigator
Recruiting
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, CH-1011, Switzerland
Contact, 41213140351
Michel Gilliet, Principal Investigator
Recruiting
Kantonsspital St. Gallen, Sankt Gallen, 9007, Switzerland
Contact, 41714942030
Antonio Cozzio, Principal Investigator
Recruiting
Changhua Christian Medical Foundation Changhua Christian Hospital, Changhua, 50004, Taiwan
Completed
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, 833, Taiwan
Recruiting
Chung Shan Medical University Hospital, Taichung, 40201, Taiwan
Recruiting
Taichung Veterans General Hospital, Taichung, 40705, Taiwan
Recruiting
Taipei Veterans General Hospital, Taipei, 11217, Taiwan
Recruiting
CNE Cherkasy Regional Hospital of Cherkasy Regional Council, Cherkasy, 18009, Ukraine
Contact, +380979421791
Anna Kulyk, Principal Investigator
Recruiting
CNCE Regional Clinical Hospital of Ivano-Frankivsk Regional Council, Dept of Rheumatology, Ivano-Frankivsk, 76018, Ukraine
Contact, +380503388571
Roman Yatsyshyn, Principal Investigator
Recruiting
Medical Center Artes Medicum LLC, Kyiv, 02002, Ukraine
Contact, +380505048489
Mykhailo Puhach, Principal Investigator
Recruiting
Med Center 'Ok!Clinic+' LLC "International Institute of Clinical Research", Kyiv, 02091, Ukraine
Viktoriia Kachur, Principal Investigator
Recruiting
Communal Enterprise Volyn Regional Clinical Hospital of Volyn Regional Council, Lutsk, 43005, Ukraine
Contact, +380332773119
Nataliia Sydor, Principal Investigator
Recruiting
UH of State NPE "Danulo Halytsky NMU in Lviv" CID, Rheum. Dept. of Marian Panchyshyn Campus, Lviv, 79010, Ukraine
Contact, +380322767603
Valentyna Chopyak, Principal Investigator
Recruiting
CNE Ternopil Reg Clinical Hospital TRC, Dept of Rheumatology, SHEI I.Ya.HorbachevskyiTernopil SMU, Ternopil, 46002, Ukraine
Contact, +380352273378
Svitlana Smiyan, Principal Investigator
Recruiting
ZAKARPATTIA ENDOCLINIC LLC, Medical Center Endoclinic, Uzhhorod, 88000, Ukraine
Contact, +380506690367
Kornelia Hranchak, Principal Investigator
Recruiting
Private Small Enterprise Medical Center Pulse, Vinnytsia, 21001, Ukraine
Contact, +380682093343
Maryna Ziabchenko, Principal Investigator
Recruiting
СNE M.I. Pyrogov RCH of Vinnytsia RC HSC Reum Osteo Bio Th, Vinnytsia, 21018, Ukraine
Contact, +380506986684
Mykola Stanislavchuk, Principal Investigator
Recruiting
Greater London
Whipps Cross University Hospital, London, Greater London, E11 1NR, United Kingdom
Contact, 4420853955226730
Anthony Bewley, Principal Investigator
Recruiting
Greater Manchester
Manchester Royal Infirmary, Manchester, Greater Manchester, M13 9WL, United Kingdom
Contact, 441612761234
Benjamin J Parker, Principal Investigator
Recruiting
West Midlands
Queen Elizabeth Hospital, Birmingham, West Midlands, B15 2GW, United Kingdom
Contact, 441216272000
Agustin Martin-Clavijo, Principal Investigator
Recruiting
West Yorkshire
Chapel Allerton Hospital, Leeds, West Yorkshire, LS9 7TF, United Kingdom
Contact, 441133924357
Philip M Laws, Principal Investigator
Recruiting