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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer Phase 2, Phase 3 990

Recruiting
Clinical Trial NCT07221357 is designed to study Treatment for Untreated, Unresectable, or Metastatic Colorectal Cancer. It is a Phase 2 Phase 3 interventional study that is recruiting, having started on December 31, 2025, with plans to enroll 990 participants. Led by Bristol-Myers Squibb, it is expected to complete by March 11, 2034. The latest data from ClinicalTrials.gov was last updated on March 31, 2026.
Brief Summary
The purpose of this study is to evaluate the safety and efficacy of pumitamig in combination with chemotherapy versus bevacizumab in combination with chemotherapy in participants with previously untreated, unresectable, or metastatic colorectal cancer
Official Title

ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Conditions
Untreated, Unresectable, or Metastatic Colorectal Cancer
Other Study IDs
  • CA266-0003
  • 2025-523224-45 (Other Identifier) (EU CT Number)
  • U1111-1325-6505 (Other Identifier) (UTN)
NCT ID Number
NCT07221357
Start Date (Actual)
2025-12-31
Last Update Posted
2026-03-31
Completion Date (Estimated)
2034-03-11
Enrollment (Estimated)
990
Study Type
Interventional
PHASE
Phase 2
Phase 3
Status
Recruiting
Keywords
Metastatic Colorectal Cancer (mCRC)
Primary Purpose
Treatment
Design Allocation
Randomized
Interventional Model
Parallel
Masking
Double
Arms / Interventions
Participant Group/ArmIntervention/Treatment
ExperimentalArm A1
Pumitamig
Specified dose on specified days
FOLFOX
Specified dose on specified days
FOLFIRI
Specified dose on specified days
ExperimentalArm A2
Pumitamig
Specified dose on specified days
FOLFOX
Specified dose on specified days
FOLFIRI
Specified dose on specified days
OtherArm B
FOLFOX
Specified dose on specified days
FOLFIRI
Specified dose on specified days
Bevacizumab
Specified dose on specified days
ExperimentalArm C
Pumitamig
Specified dose on specified days
FOLFOX
Specified dose on specified days
FOLFIRI
Specified dose on specified days
CAPOX
Specified dose on specified days
OtherArm D
FOLFOX
Specified dose on specified days
FOLFIRI
Specified dose on specified days
Bevacizumab
Specified dose on specified days
CAPOX
Specified dose on specified days
Primary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
Objective Response (OR) (confirmed complete response (CR) or partial response (PR)) by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 per investigator assessment
Phase 2
Up to 5 years
Progression Free Survival (PFS) by RECIST v1.1 per blinded independent central review (BICR)
Phase 3
Up to 5 years
Secondary Outcome Measures
Outcome MeasureMeasure DescriptionTime Frame
PFS by RECIST v1.1 per investigator assessment
Phase 2
Up to 5 years
Duration of Response (DOR) (CR or PR) by RECIST v1.1 per investigator assessment
Phase 2
Up to 5 years
Time to Response (TTR) (CR or PR) by RECIST v1.1 per investigator assessment
Phase 2
Up to 5 years
Disease control (Best Overall Response (BOR) of confirmed CR, confirmed PR, or Stable Disease (SD)) by RECIST v1.1 per investigator assessment
Phase 2
Up to 5 years
Recommended dose of Pumitamig for Phase 3
Phase 2
Up to 5 years
Overall Survival (OS)
Phase 3
Up to 5 years
OR by RECIST v1.1 per BICR
Phase 3
Up to 5 years
DOR by RECIST v1.1 per BICR
Phase 3
Up to 5 years
Participation Assistant
Eligibility Criteria

Eligible Ages
Adult, Older Adult
Minimum Age
18 Years
Eligible Sexes
All
  • Participant must previously untreated, histologically confirmed recurrent or metastatic colorectal adenocarcinoma, not amenable to curative surgery.
  • Participant must have no known presence of mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) colorectal cancer (CRC) per historical results (a validated test should be used).
  • Participant must have no known presence of the gene that encodes the protein B-Raf (BRAF) V600E mutation per local testing.
  • Participant must have measurable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.

  • Participant must not have any untreated known central nervous system (CNS) metastases including brain, leptomeningeal and/or spinal cord compression.
  • Participant must not have any prior malignancy active within the previous 2 years, except for locally curable cancers that have been apparently cured and considered to be of low risk of recurrence.
  • Participant must not have significant cardiovascular disease, such as myocardial infarction, unstable angina, arterial thrombosis or cerebrovascular accident within 6 months prior to randomization, uncontrolled hypertension (≥ 160 systolic, ≥ 100 diastolic mm Hg) despite optimal medical management, or congenital long QT syndrome.
  • Participant must not have prior systemic treatment with an anti-PD-1, anti-programmed death (ligand)-1 (PD-L1), anti-PD-L2, CD137 agonists, or anti-cytotoxic T-lymphocyte associated protein 4 (CTLA-4) antibody, or any other antibody or drug specifically targeting T cell co-stimulation or checkpoint pathways or chemotherapy.
  • Other protocol-defined Inclusion/Exclusion criteria apply.
Bristol-Myers Squibb logoBristol-Myers Squibb
Study Central Contact
Contact: BMS Clinical Trials Contact Center www.BMSClinicalTrials.com, 855-907-3286, [email protected]
Contact: First line of the email MUST contain NCT # and Site #.
263 Study Locations in 26 Countries

Arizona

Local Institution - 0428, Tucson, Arizona, 85724, United States
Site 0428, Contact
Not yet recruiting

Arkansas

Local Institution - 0432, Springdale, Arkansas, 72762, United States
Site 0432, Contact
Not yet recruiting

California

USC/Norris Comprehensive Cancer Center, Los Angeles, California, 90033, United States
Sandra Algaze, Site 0263, Contact, 818-406-8072
Recruiting
Local Institution - 0345, Orange, California, 92868, United States
Site 0345, Contact
Not yet recruiting
Local Institution - 0317, San Francisco, California, 94115, United States
Site 0317, Contact
Not yet recruiting
Local Institution - 0330, Santa Monica, California, 90404, United States
Site 0330, Contact
Not yet recruiting
Local Institution - 0293, Stanford, California, 94305, United States
Site 0293, Contact
Not yet recruiting

Florida

Florida Cancer Specialists - East, Cape Coral, Florida, 33990, United States
Todd Gersten, Site 0574, Contact, 561-366-4100
Recruiting
Florida Cancer Specialists - North, St. Petersburg, Florida, 33705, United States
Maen Hussein, Site 0575, Contact, 727-216-1143
Recruiting
Local Institution - 0269, Tampa, Florida, 33612, United States
Site 0269, Contact
Not yet recruiting

Georgia

Local Institution - 0276, Duluth, Georgia, 30096, United States
Site 0276, Contact
Not yet recruiting
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital, Marietta, Georgia, 30060, United States
Walid Shaib, Site 0369, Contact, 770-281-5124
Recruiting

Illinois

Local Institution - 0030, Chicago, Illinois, 60611, United States
Site 0030, Contact
Not yet recruiting
Local Institution - 0433, Chicago, Illinois, 60637, United States
Site 0433, Contact
Not yet recruiting

Iowa

Local Institution - 0335, Iowa City, Iowa, 52242, United States
Site 0335, Contact
Not yet recruiting

Maryland

Local Institution - 0262, Baltimore, Maryland, 21287, United States
Site 0262, Contact
Not yet recruiting
Maryland Oncology Hematology - Silver Spring, Silver Spring, Maryland, 20904, United States
Danubia Hester, Site 0580, Contact
Recruiting

Massachusetts

Local Institution - 0471, Boston, Massachusetts, 02114, United States
Withdrawn

Michigan

Local Institution - 0430, Ann Arbor, Michigan, 48109, United States
Site 0430, Contact
Not yet recruiting
Local Institution - 0254, Grand Rapids, Michigan, 49546, United States
Site 0254, Contact
Not yet recruiting

Minnesota

Minnesota Oncology, Maple Grove, Minnesota, 55369, United States
Robert Delaune, Site 0572, Contact
Recruiting

Missouri

Local Institution - 0318, Kansas City, Missouri, 64111, United States
Site 0318, Contact
Not yet recruiting
Washington University School OF Medicine-Siteman Cancer Center, St Louis, Missouri, 63110, United States
Moh'd Khushman, Site 0336, Contact, 314-273-3564
Recruiting

Nebraska

Local Institution - 0334, Omaha, Nebraska, 68198, United States
Site 0334, Contact
Not yet recruiting

New York

Northwell Health/ RJ Zuckerberg Cancer Center, Lake Success, New York, 11042, United States
Nicholas Hornstein, Site 0429, Contact, 323-533-7275
Recruiting
Local Institution - 0270, Mineola, New York, 11501, United States
Site 0270, Contact
Not yet recruiting
Local Institution - 0273, New Hyde Park, New York, 11042, United States
Site 0273, Contact
Not yet recruiting

North Carolina

Local Institution - 0290, Charlotte, North Carolina, 28207, United States
Site 0290, Contact
Not yet recruiting

North Dakota

Local Institution - 0526, Fargo, North Dakota, 58102, United States
Site 0526, Contact
Not yet recruiting

Ohio

Local Institution - 0339, Columbus, Ohio, 43210, United States
Site 0339, Contact
Not yet recruiting

Oklahoma

Local Institution - 0605, Oklahoma City, Oklahoma, 73104, United States
Site 0605, Contact
Not yet recruiting

Pennsylvania

Lehigh Valley Health Network, Allentown, Pennsylvania, 18103, United States
Maged Khalil, Site 0348, Contact, 610-402-9543
Recruiting
Local Institution - 0604, Pittsburgh, Pennsylvania, 15232, United States
Site 0604, Contact
Not yet recruiting

South Dakota

Local Institution - 0312, Sioux Falls, South Dakota, 57104, United States
Site 0312, Contact
Not yet recruiting

Tennessee

Local Institution - 0333, Nashville, Tennessee, 37203, United States
Site 0333, Contact
Not yet recruiting
Sarah Cannon Institute, Nashville, Tennessee, 37203, United States
Meredith Pelster, Site 0570, Contact, 615-986-4366
Recruiting

Texas

Texas Oncology Dallas Fort Worth West (DFWW) - Arlington Cancer Center North, Arlington, Texas, 76012, United States
Laith Abushahin, Site 0573, Contact
Recruiting
Texas Oncology, PA, Austin, Texas, 78705, United States
Vivian Cline, Site 0571, Contact, 512-427-9400
Recruiting
Local Institution - 0252, Houston, Texas, 77030, United States
Site 0252, Contact
Not yet recruiting
Texas Oncology - San Antonio, San Antonio, Texas, 78240, United States
Sridhar Beeram, Site 0576, Contact, 210-615-1988
Recruiting

Utah

Local Institution - 0426, Salt Lake City, Utah, 84102, United States
Site 0426, Contact
Not yet recruiting

Virginia

Local Institution - 0278, Fairfax, Virginia, 22031, United States
Site 0278, Contact
Not yet recruiting
Virginia Oncology Associates, Norfolk, Virginia, 23502, United States
Yue Zhang, Site 0577, Contact
Recruiting

Washington

Local Institution - 0491, Edmonds, Washington, 98026-8032, United States
Site 0491, Contact
Not yet recruiting
Local Institution - 0253, Seattle, Washington, 98109, United States
Site 0253, Contact
Not yet recruiting
Northwest Cancer Specialists, P.C., Vancouver, Washington, 98684, United States
Spencer Shao, Site 0578, Contact, 503-528-5005
Recruiting

Alberta

Local Institution - 0550, Calgary, Alberta, T2N 5G2, Canada
Site 0550, Contact
Not yet recruiting

Nova Scotia

Local Institution - 0260, Halifax, Nova Scotia, B3H 3A7, Canada
Site 0260, Contact
Not yet recruiting

Ontario

Local Institution - 0255, Ottawa, Ontario, K1H 8L6, Canada
Site 0255, Contact
Not yet recruiting
Local Institution - 0421, Toronto, Ontario, M5G 2M9, Canada
Site 0421, Contact
Not yet recruiting

Quebec

Local Institution - 0258, Montreal, Quebec, H2X 3E4, Canada
Site 0258, Contact
Not yet recruiting
Jewish General Hospital, Montreal, Quebec, H3T 1E2, Canada
Petr Kavan, Site 0423, Contact, 5143408222ext23460
Recruiting
Local Institution - 0261, Sherbrooke, Quebec, J1H 5N4, Canada
Site 0261, Contact
Not yet recruiting

Buenos Aires F.D.

Local Institution - 0071, ABB, Buenos Aires F.D., C1199ABB, Argentina
Site 0071, Contact
Not yet recruiting
Local Institution - 0174, Buenos Aires, 1039, Argentina
Site 0174, Contact
Not yet recruiting
Local Institution - 0073, Buenos Aires, C1280AEB, Argentina
Site 0073, Contact
Not yet recruiting
Local Institution - 0069, Buenos Aires, C1426ANZ, Argentina
Site 0069, Contact
Not yet recruiting
Local Institution - 0172, Buenos Aires, C1431FWO, Argentina
Site 0172, Contact
Not yet recruiting

New South Wales

Local Institution - 0277, Liverpool, New South Wales, 2170, Australia
Site 0277, Contact
Not yet recruiting
Local Institution - 0157, St Leonards, New South Wales, 2065, Australia
Site 0157, Contact
Not yet recruiting

Queensland

Local Institution - 0274, Birtinya, Queensland, 4575, Australia
Site 0274, Contact
Not yet recruiting
Royal Brisbane and Women's Hospital, Brisbane, Queensland, 4029, Australia
Matthew Burge, Site 0215, Contact, 61736468111
Recruiting
Local Institution - 0191, Woolloongabba, Queensland, 4102, Australia
Site 0191, Contact
Not yet recruiting

South Australia

Local Institution - 0156, Adelaide, South Australia, 5042, Australia
Site 0156, Contact
Not yet recruiting
Lyell McEwin Hospital, Elizabeth Vale, South Australia, 5112, Australia
Christopher Hocking, Site 0155, Contact, 0871177265
Recruiting

Victoria

Local Institution - 0196, Ballarat Central, Victoria, 3350, Australia
Site 0196, Contact
Not yet recruiting
Local Institution - 0190, Epping, Victoria, 3076, Australia
Site 0190, Contact
Not yet recruiting
Local Institution - 0194, Shepparton, Victoria, 3630, Australia
Site 0194, Contact
Not yet recruiting
Local Institution - 0519, St Albans, Victoria, 3021, Australia
Site 0519, Contact
Not yet recruiting

Western Australia

St. John of God Murdoch Hospital, Murdoch, Western Australia, 6150, Australia
Kynan Feeney, Site 0154, Contact, +61894389599
Recruiting
Local Institution - 0160, Malvern, 3144, Australia
Site 0160, Contact
Not yet recruiting
Local Institution - 0159, Wentworthville, NSW2145, Australia
Site 0159, Contact
Not yet recruiting
Local Institution - 0078, Linz, 4010, Austria
Site 0078, Contact
Not yet recruiting
Local Institution - 0178, Salzburg, 5020, Austria
Site 0178, Contact
Not yet recruiting
Local Institution - 0082, Vienna, A-1090, Austria
Site 0082, Contact
Not yet recruiting

Antwerpen

Local Institution - 0622, Bonheiden, Antwerpen, 2820, Belgium
Site 0622, Contact
Not yet recruiting
Local Institution - 0103, Edegem, Antwerpen, 2650, Belgium
Site 0103, Contact
Not yet recruiting

Hainaut

Local Institution - 0620, Charleroi, Hainaut, 6060, Belgium
Site 0620, Contact
Not yet recruiting

MO

Local Institution - 0179, Brussels, MO, 1200, Belgium
Site 0179, Contact
Not yet recruiting

West-Vlaanderen

Local Institution - 0122, Roeselare, West-Vlaanderen, 8800, Belgium
Site 0122, Contact
Not yet recruiting
Local Institution - 0118, Brussels, 1000, Belgium
Site 0118, Contact
Not yet recruiting
Local Institution - 0115, Leuven, 3000, Belgium
Site 0115, Contact
Not yet recruiting

Paraná

Local Institution - 0267, Curitiba, Paraná, 81480-580, Brazil
Site 0267, Contact
Not yet recruiting

Rio Grande do Norte

Local Institution - 0331, Natal/RN, Rio Grande do Norte, 59062-000, Brazil
Site 0331, Contact
Not yet recruiting

Rio Grande do Sul

Local Institution - 0375, Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Site 0375, Contact
Not yet recruiting
Local Institution - 0342, Porto Alegre, Rio Grande do Sul, 91610-000, Brazil
Site 0342, Contact
Not yet recruiting
Local Institution - 0373, Santa Cruz do Sul, Rio Grande do Sul, 96810-110, Brazil
Site 0373, Contact
Not yet recruiting

Santa Catarina

Local Institution - 0444, Chapecó, Santa Catarina, 89812-211, Brazil
Site 0444, Contact
Not yet recruiting

São Paulo

Local Institution - 0266, Barretos, São Paulo, 14784400, Brazil
Site 0266, Contact
Not yet recruiting
Local Institution - 0264, São José do Rio Preto, 15090-000, Brazil
Site 0264, Contact
Not yet recruiting
Local Institution - 0268, São Paulo, 01246-000, Brazil
Site 0268, Contact
Not yet recruiting
Local Institution - 0341, São Paulo, 01308-060, Brazil
Site 0341, Contact
Not yet recruiting

Santiago Metropolitan

Local Institution - 0171, Recoleta, Santiago Metropolitan, 8420391, Chile
Site 0171, Contact
Not yet recruiting
Local Institution - 0463, Santiago, Santiago Metropolitan, 7500921, Chile
Site 0463, Contact
Not yet recruiting
Local Institution - 0175, Santiago, Santiago Metropolitan, 7620002, Chile
Site 0175, Contact
Not yet recruiting

Anhui

Local Institution - 0595, Hefei, Anhui, 230601, China
Site 0595, Contact
Not yet recruiting

Chongqing Municipality

Local Institution - 0499, Chongqing, Chongqing Municipality, 400030, China
Site 0499, Contact
Not yet recruiting

Fujian

Local Institution - 0354, Fuzhou, Fujian, 350014, China
Site 0354, Contact
Not yet recruiting
Local Institution - 0388, Fuzhou Fujian, Fujian, 350001, China
Site 0388, Contact
Not yet recruiting

Guangdong

Local Institution - 0414, Guangzhou, Guangdong, 510000, China
Site 0414, Contact
Not yet recruiting
Local Institution - 0130, Guangzhou, Guangdong, 510555, China
Site 0130, Contact
Not yet recruiting

Hebei

Local Institution - 0390, Tianjin, Hebei, 300060, China
Site 0390, Contact
Not yet recruiting

Heilongjiang

Local Institution - 0353, Harbin, Heilongjiang, 150081, China
Site 0353, Contact
Not yet recruiting

Henan

Local Institution - 0384, Nanyang, Henan, 473009, China
Site 0384, Contact
Not yet recruiting

Hubei

Local Institution - 0391, Wuhan, Hubei, 430079, China
Site 0391, Contact
Not yet recruiting

Hunan

Local Institution - 0376, Changsha, Hunan, 410013, China
Site 0376, Contact
Not yet recruiting
Local Institution - 0411, Changsha, Hunan, 410031, China
Site 0411, Contact
Not yet recruiting

Jiangsu

Local Institution - 0398, Yangzhou, Jiangsu, 225001, China
Site 0398, Contact
Not yet recruiting

Jiangxi

Local Institution - 0381, Nanchang, Jiangxi, 330006, China
Site 0381, Contact
Not yet recruiting

Liaoning

Local Institution - 0352, Shenyang, Liaoning, 110001, China
Site 0352, Contact
Not yet recruiting
Local Institution - 0355, Shenyang, Liaoning, 110042, China
Site 0355, Contact
Not yet recruiting

Shandong

Local Institution - 0382, Jinan, Shandong, 250117, China
Site 0382, Contact
Not yet recruiting

Shanghai Municipality

Local Institution - 0378, Shanghai, Shanghai Municipality, 200120, China
Site 0378, Contact
Not yet recruiting

Sichuan

Local Institution - 0498, Chengdu, Sichuan, 610041, China
Site 0498, Contact
Not yet recruiting

Zhejiang

Local Institution - 0360, Hangzhou, Zhejiang, 310003, China
Site 0360, Contact
Not yet recruiting
Local Institution - 0383, Hangzhou, Zhejiang, 310022, China
Site 0383, Contact
Not yet recruiting
Local Institution - 0409, Beijing, 100034, China
Site 0409, Contact
Not yet recruiting
Local Institution - 0457, Hangzhou, 310009, China
Site 0457, Contact
Not yet recruiting
Local Institution - 0416, Nanjing, Jiangsu, 210009, China
Site 0416, Contact
Not yet recruiting
Local Institution - 0356, Shanghai, 200032, China
Site 0356, Contact
Not yet recruiting
Local Institution - 0412, Wuhan, 430022, China
Site 0412, Contact
Not yet recruiting

Praha 10

Local Institution - 0489, Prague, Praha 10, 10034, Czechia
Site 0489, Contact
Not yet recruiting

Praha 5

Local Institution - 0248, Prague, Praha 5, 150 06, Czechia
Site 0248, Contact
Not yet recruiting

Praha, Hlavní Mesto

Local Institution - 0461, Prague, Praha, Hlavní Mesto, 12808, Czechia
Site 0461, Contact
Not yet recruiting
Local Institution - 0180, Brno, 656 53, Czechia
Site 0180, Contact
Not yet recruiting
Local Institution - 0188, Hradec Králové, 500 05, Czechia
Site 0188, Contact
Not yet recruiting
Local Institution - 0467, Olomouc, 77520, Czechia
Site 0467, Contact
Not yet recruiting

Bouches-du-Rhône

Local Institution - 0202, Marseille, Bouches-du-Rhône, 13385, France
Site 0202, Contact
Not yet recruiting

Doubs

Local Institution - 0590, Besançon, Doubs, 25000, France
Site 0590, Contact
Not yet recruiting

Loire-Atlantique

Local Institution - 0182, Saint-Herblain, Loire-Atlantique, 44805, France
Site 0182, Contact
Not yet recruiting

Morbihan

Local Institution - 0618, Lorient, Morbihan, 56100, France
Site 0618, Contact
Not yet recruiting

Nord

Local Institution - 0613, Lille, Nord, 59020, France
Site 0613, Contact
Not yet recruiting

Pays de la Loire Region

Local Institution - 0125, Nantes, Pays de la Loire Region, 44093, France
Site 0125, Contact
Not yet recruiting

Provence-Alpes-Côte d'Azur Region

Local Institution - 0121, Marseille, Provence-Alpes-Côte d'Azur Region, 13273, France
Site 0121, Contact
Not yet recruiting
Local Institution - 0138, Dijon, 21000, France
Site 0138, Contact
Not yet recruiting
Local Institution - 0616, Limoges, 87042, France
Site 0616, Contact
Not yet recruiting
Hôpital Saint Antoine, Paris, 75571, France
Thierry Andre, Site 0183, Contact, 33149282954
Recruiting
Local Institution - 0181, Pessac, 33064, France
Site 0181, Contact
Not yet recruiting
Local Institution - 0127, Rouen, 76000, France
Site 0127, Contact
Not yet recruiting
Local Institution - 0097, Toulose, 31059, France
Site 0097, Contact
Not yet recruiting
Local Institution - 0098, Villejuif, 94805, France
Site 0098, Contact
Not yet recruiting

Bavaria

Local Institution - 0591, Erlangen, Bavaria, 91054, Germany
Site 0591, Contact
Not yet recruiting

Lower Saxony

Local Institution - 0607, Hanover, Lower Saxony, 30161, Germany
Site 0607, Contact
Not yet recruiting

Saxony

Local Institution - 0033, Dresden, Saxony, 01307, Germany
Site 0033, Contact
Not yet recruiting
Local Institution - 0035, Berlin, 10117, Germany
Site 0035, Contact
Not yet recruiting
Local Institution - 0061, Bochum, 44791, Germany
Site 0061, Contact
Not yet recruiting
Local Institution - 0588, Chemnitz, 09113, Germany
Site 0588, Contact
Not yet recruiting
Local Institution - 0057, Düsseldorf, 40479, Germany
Site 0057, Contact
Not yet recruiting
Local Institution - 0040, Frankfurt, 60488, Germany
Site 0040, Contact
Not yet recruiting
Local Institution - 0058, Göttingen, 37075, Germany
Site 0058, Contact
Not yet recruiting
Local Institution - 0039, Hamburg, 20249, Germany
Site 0039, Contact
Not yet recruiting
Local Institution - 0594, Hamburg, 22763, Germany
Site 0594, Contact
Not yet recruiting
Local Institution - 0041, Leipzig, D-04103, Germany
Site 0041, Contact
Not yet recruiting
Local Institution - 0060, Mainz, 55131, Germany
Site 0060, Contact
Not yet recruiting
Local Institution - 0059, Mannheim, 68167, Germany
Site 0059, Contact
Not yet recruiting
Klinikum Neuperlach, München, 81737, Germany
Stefan Boeck, Site 0034, Contact
Recruiting
Local Institution - 0037, Ulm, 89081, Germany
Site 0037, Contact
Not yet recruiting
Local Institution - 0203, Veszprém, 8200, Hungary
Site 0203, Contact
Not yet recruiting

Dādra and Nagar Haveli and Damān and Diu

Local Institution - 0010, Nashik, Dādra and Nagar Haveli and Damān and Diu, 422001, India
Site 0010, Contact
Not yet recruiting

Maharashtra

Local Institution - 0036, Mumbai, Maharashtra, 400012, India
Site 0036, Contact
Not yet recruiting
Local Institution - 0552, Mumbai, Maharashtra, 400036, India
Site 0552, Contact
Not yet recruiting
Local Institution - 0006, Delhi, 110029, India
Site 0006, Contact
Not yet recruiting
Local Institution - 0554, Delhi, 110029, India
Site 0554, Contact
Not yet recruiting
Local Institution - 0557, Puducherry, 605006, India
Site 0557, Contact
Not yet recruiting
Local Institution - 0038, Pune, 411001, India
Site 0038, Contact
Not yet recruiting

Bari

Local Institution - 0617, Castellana Grotte, Bari, 70013, Italy
Site 0617, Contact
Not yet recruiting

Foggia

Local Institution - 0584, San Giovanni Rotondo, Foggia, 71013, Italy
Site 0584, Contact
Not yet recruiting

Lecce

Local Institution - 0619, Tricase, Lecce, 73039, Italy
Site 0619, Contact
Not yet recruiting

Milano

Local Institution - 0231, Milan, Milano, 20162, Italy
Site 0231, Contact
Not yet recruiting
Local Institution - 0609, Avellino, 83100, Italy
Site 0609, Contact
Not yet recruiting
Local Institution - 0227, Catania, 95124, Italy
Site 0227, Contact
Not yet recruiting
Local Institution - 0615, La Spezia, 19124, Italy
Site 0615, Contact
Not yet recruiting
Local Institution - 0111, Milan, 20133, Italy
Site 0111, Contact
Not yet recruiting
Local Institution - 0236, Naples, 80131, Italy
Site 0236, Contact
Not yet recruiting
Local Institution - 0221, Padova, 35128, Italy
Site 0221, Contact
Not yet recruiting
Local Institution - 0226, Pisa, 56126, Italy
Site 0226, Contact
Not yet recruiting
Local Institution - 0612, Ravenna, 48121, Italy
Site 0612, Contact
Not yet recruiting
Local Institution - 0233, Reggio Emilia, 42123, Italy
Site 0233, Contact
Not yet recruiting

Chiba

Local Institution - 0053, Chiba, Chiba, 260-8717, Japan
Site 0053, Contact
Not yet recruiting

Ehime

Local Institution - 0045, Matsuyama, Ehime, 791-0280, Japan
Site 0045, Contact
Not yet recruiting

Hokkaido

Hokkaido University Hospital, Sapporo, Hokkaido, 0608648, Japan
Yoshito Komatsu, Site 0051, Contact, 81117065657
Recruiting

Hyōgo

Local Institution - 0047, Kobe, Hyōgo, 6500047, Japan
Site 0047, Contact
Not yet recruiting

Kanagawa

Local Institution - 0056, Yokohama, Kanagawa, 2418515, Japan
Site 0056, Contact
Not yet recruiting

Okayama-ken

Local Institution - 0476, Kurashiki, Okayama-ken, 710-8602, Japan
Site 0476, Contact
Not yet recruiting

Osaka

The University of Osaka Hospital, Suita, Osaka, 565-0871, Japan
Taroh Satoh, Site 0066, Contact, 81668795111
Recruiting
Local Institution - 0521, Takatsuki, Osaka, 569-8686, Japan
Site 0521, Contact
Not yet recruiting

Saitama

Local Institution - 0046, Hidaka, Saitama, 350-1298, Japan
Site 0046, Contact
Not yet recruiting

Tokyo

Local Institution - 0475, Chuo-ku, Tokyo, 104-0045, Japan
Site 0475, Contact
Not yet recruiting
The Cancer Institute Hospital of JFCR, Koto-ku, Tokyo, 135-8550, Japan
Kensei Yamaguchi, Site 0044, Contact, 81335200111
Recruiting
Local Institution - 0473, Chikusa-ku, 464-8681, Japan
Site 0473, Contact
Not yet recruiting
Local Institution - 0052, Fukuoka, 811-1395, Japan
Site 0052, Contact
Not yet recruiting
Local Institution - 0493, Kashiwa, 277-8577, Japan
Site 0493, Contact
Not yet recruiting
Local Institution - 0597, Kitaadachi-gun, 362-0806, Japan
Site 0597, Contact
Not yet recruiting
Local Institution - 0506, Osaka, 541-8567, Japan
Site 0506, Contact
Not yet recruiting
Local Institution - 0067, Sendai, 980-8574, Japan
Site 0067, Contact
Not yet recruiting
Local Institution - 0054, Sunto-gun, 411-8777, Japan
Site 0054, Contact
Not yet recruiting

North Brabant

Local Institution - 0173, Eindhoven, North Brabant, 5623 EJ, Netherlands
Site 0173, Contact
Not yet recruiting

North Holland

Local Institution - 0112, Amsterdam, North Holland, 1105 AZ, Netherlands
Site 0112, Contact
Not yet recruiting
Local Institution - 0170, Groningen, 9713 GZ, Netherlands
Site 0170, Contact
Not yet recruiting
Local Institution - 0216, Tilburg, 5022 GC, Netherlands
Site 0216, Contact
Not yet recruiting
Local Institution - 0167, Utrecht, 3543 AZ, Netherlands
Site 0167, Contact
Not yet recruiting

Lesser Poland Voivodeship

Local Institution - 0364, Krakow, Lesser Poland Voivodeship, 31-826, Poland
Site 0364, Contact
Not yet recruiting

Lower Silesian Voivodeship

Local Institution - 0452, Jelenia Góra, Lower Silesian Voivodeship, 58-506, Poland
Site 0452, Contact
Not yet recruiting

Masovian Voivodeship

Luxmed Onkologia sp. z o. o., Warsaw, Masovian Voivodeship, 01-748, Poland
Pawel Morawski, Site 0363, Contact, 48693100299
Recruiting
Local Institution - 0525, Warsaw, Masovian Voivodeship, 02-507, Poland
Site 0525, Contact
Not yet recruiting
Local Institution - 0359, Warsaw, Masovian Voivodeship, 03-411, Poland
Site 0359, Contact
Not yet recruiting

Podkarpackie Voivodeship

Local Institution - 0365, Brzozów, Podkarpackie Voivodeship, 36-200, Poland
Site 0365, Contact
Not yet recruiting

Pomeranian Voivodeship

Local Institution - 0626, Gdansk, Pomeranian Voivodeship, 80-219, Poland
Site 0626, Contact
Not yet recruiting

Silesian Voivodeship

Local Institution - 0451, Gliwice, Silesian Voivodeship, 44-101, Poland
Site 0451, Contact
Not yet recruiting

West Pomeranian Voivodeship

Local Institution - 0361, Koszalin, West Pomeranian Voivodeship, 75-581, Poland
Site 0361, Contact
Not yet recruiting
Local Institution - 0362, Opole, 45-372, Poland
Site 0362, Contact
Not yet recruiting

Cluj

Local Institution - 0282, Cluj-Napoca, Cluj, 400162, Romania
Site 0282, Contact
Not yet recruiting
Local Institution - 0100, Bucharest, 22328, Romania
Site 0100, Contact
Not yet recruiting
Local Institution - 0142, Cluj-Napoca, 400015, Romania
Site 0142, Contact
Not yet recruiting
Local Institution - 0189, Craiova, 200347, Romania
Site 0189, Contact
Not yet recruiting
Local Institution - 0370, Iași, 700106, Romania
Site 0370, Contact
Not yet recruiting
Local Institution - 0143, Iași, 700483, Romania
Site 0143, Contact
Not yet recruiting

Central Singapore

Local Institution - 0145, Singapore, Central Singapore, 168583, Singapore
Site 0145, Contact
Not yet recruiting
Local Institution - 0147, Singapore, 119074, Singapore
Site 0147, Contact
Not yet recruiting
Local Institution - 0285, Singapore, 308442, Singapore
Site 0285, Contact
Not yet recruiting
Local Institution - 0511, Singapore, 329563, Singapore
Site 0511, Contact
Not yet recruiting

Gyeonggido

Local Institution - 0406, Seongnam, Gyeonggido, 13620, South Korea
Site 0406, Contact
Not yet recruiting

Seoul-teukbyeolsi [Seoul]

Seoul National University Hospital, Seoul, Seoul-teukbyeolsi [Seoul], 03080, South Korea
Sae-Won Han, Site 0404, Contact, 82-2-2072-0242
Recruiting
Asan Medical Center, Seoul, Seoul-teukbyeolsi [Seoul], 05505, South Korea
Jeong Eun Kim, Site 0492, Contact, 82230103945
Recruiting
Local Institution - 0394, Seoul, Seoul-teukbyeolsi [Seoul], 06351, South Korea
Site 0394, Contact
Not yet recruiting
Local Institution - 0395, Seoul, Seoul-teukbyeolsi [Seoul], 06591, South Korea
Site 0395, Contact
Not yet recruiting
Local Institution - 0405, Seoul, 120-752, South Korea
Site 0405, Contact
Not yet recruiting

Barcelona [Barcelona]

Local Institution - 0163, Badalona, Barcelona [Barcelona], 08916, Spain
Site 0163, Contact
Not yet recruiting
Local Institution - 0240, Barcelona, Barcelona [Barcelona], 08035, Spain
Site 0240, Contact
Not yet recruiting

Madrid, Comunidad de

Local Institution - 0624, Madrid, Madrid, Comunidad de, 28034, Spain
Site 0624, Contact
Not yet recruiting
Local Institution - 0229, Madrid, Madrid, Comunidad de, 28041, Spain
Site 0229, Contact
Not yet recruiting

Navarre

Local Institution - 0225, Pamplona, Navarre, 31009, Spain
Site 0225, Contact
Not yet recruiting
Local Institution - 0472, Elche (alicante), 03203, Spain
Site 0472, Contact
Not yet recruiting
Hospital General Universitario Gregorio Marañon, Madrid, 28007, Spain
Pilar Garcia Alfonso, Site 0228, Contact, 34914269394
Recruiting
Local Institution - 0232, Málaga, 29011, Spain
Site 0232, Contact
Not yet recruiting
Local Institution - 0625, Salamanca, 37007, Spain
Site 0625, Contact
Not yet recruiting
Local Institution - 0593, Santiago de Compostela, 15706, Spain
Site 0593, Contact
Not yet recruiting
Local Institution - 0234, Seville, 41013, Spain
Site 0234, Contact
Not yet recruiting

Stockholm County

Local Institution - 0074, Stockholm, Stockholm County, 17176, Sweden
Site 0074, Contact
Not yet recruiting

Västra Götaland County

Local Institution - 0185, Gothenburg, Västra Götaland County, 41685, Sweden
Site 0185, Contact
Not yet recruiting
Local Institution - 0400, Lund, 22184, Sweden
Site 0400, Contact
Not yet recruiting

Kaohsiung

Local Institution - 0301, Kaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan
Site 0301, Contact
Not yet recruiting
Local Institution - 0289, Kaohsiung City, 807, Taiwan
Site 0289, Contact
Not yet recruiting
Local Institution - 0291, Tainan, Taiana, 704, Taiwan
Site 0291, Contact
Not yet recruiting
Local Institution - 0297, Taipei, 100229, Taiwan
Site 0297, Contact
Not yet recruiting
Local Institution - 0300, Taipei, 11217, Taiwan
Site 0300, Contact
Not yet recruiting
Local Institution - 0449, Taoyuan District, 333, Taiwan
Site 0449, Contact
Not yet recruiting
Local Institution - 0020, Adana, 1370, Turkey (Türkiye)
Site 0020, Contact
Not yet recruiting
Local Institution - 0065, Ankara, 06100, Turkey (Türkiye)
Site 0065, Contact
Not yet recruiting
Local Institution - 0018, Erzurum, 25070, Turkey (Türkiye)
Site 0018, Contact
Not yet recruiting
Local Institution - 0296, Istanbul, 34214, Turkey (Türkiye)
Site 0296, Contact
Not yet recruiting
Local Institution - 0295, Kadiköy/Istanbul, 41380, Turkey (Türkiye)
Site 0295, Contact
Not yet recruiting

Lancashire

The Christie NHS Foundation Trust, Manchester, Lancashire, M20 4BX, United Kingdom
Michael Braun, Site 0305, Contact
Recruiting

London

Local Institution - 0600, Enfield, London, EN28JL, United Kingdom
Site 0600, Contact
Not yet recruiting

Oxfordshire

Local Institution - 0366, Oxford, Oxfordshire, OX3 7LJ, United Kingdom
Site 0366, Contact
Not yet recruiting

West Midlands

Local Institution - 0540, Birmingham, West Midlands, B15 2TT, United Kingdom
Site 0540, Contact
Not yet recruiting
Local Institution - 0601, Cardiff, CF14 2TL, United Kingdom
Site 0601, Contact
Not yet recruiting
Local Institution - 0602, Dorchester, DT1 2JY, United Kingdom
Site 0602, Contact
Not yet recruiting
Local Institution - 0307, Glasgow, G12 0YN, United Kingdom
Site 0307, Contact
Not yet recruiting
Royal Marsden Hospital Sutton, London, SM2 5PT, United Kingdom
Naureen Starling, Site 0596, Contact, 442086426011
Recruiting
Royal Marsden Hospital, London, SW3 6JJ, United Kingdom
Naureen Starling, Site 0316, Contact, 442086426011
Recruiting
Maidstone and Tunbridge Wells NHS Trust, Maidstone, ME16 9QQ, United Kingdom
Mark Hill, Site 0368, Contact, +441622225041
Recruiting
Local Institution - 0310, Newcastle upon Tyne, NE7 7DN, United Kingdom
Site 0310, Contact
Not yet recruiting